2015, Number 2
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Gac Med Mex 2015; 151 (2)
Nutritional approaches to modulate oxidative stress that induce Alzheimer’s disease. Nutritional approaches to prevent Alzheimer’s disease
Herman LH, Alanís-Garza EJ, Estrada PMF, Mureyko LL, Alarcón TDA, Ixtepan TL
Language: Spanish
References: 57
Page: 245-251
PDF size: 117.77 Kb.
ABSTRACT
Alzheimer´s disease is the most common cause of dementia in the world; symptoms first appear after age 65 and have a
progressive evolution. Expecting an increase on its incidence and knowing there is currently no cure for Alzheimer’s disease,
it is a necessity to prevent progression. The change in diet due to globalization may explain the growth of the incidence in
places such as Japan and Mediterranean countries, which used to have fewer incidences. There is a direct correlation between
disease progression and the increased intake of alcohol, saturated fats, and red meat. Therefore, we find obesity and higher
serum levels in cholesterol due to saturated fat as a result. A way to decrease the progression of Alzheimer´s is through a diet
rich in poliphenoles (potent antioxidants), unsaturated fats (monounsaturated and polyunsaturated), fish, vegetable fat, fruits with
low glycemic index, and a moderate consumption of red wine. Through this potent antioxidant diet we accomplish the prevention
of dementia and the progression of Alzheimer´s disease. This article emphasizes the food and other components that have been
demonstrated to decrease the oxidative stress related to these progressive diseases.
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