2015, Number 2
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Rev Mex Patol Clin Med Lab 2015; 62 (2)
Evaluation of tumor marker CEA and CA15-3 in patient with breast cancer
Johnson G, Valdés RYC, Polo VJC, Marcel EA
Language: Spanish
References: 13
Page: 127-132
PDF size: 256.56 Kb.
ABSTRACT
The breast cancer is one of the most frequent and heterogeneous diseases in women. In clinical, the tumor markers are employees in the prognosis and evaluation of the response to therapy. Tumor markers (CEA, CA 15-3) are useful in the follow-up and evaluation of response to treatment.
Objective: To determine the association between the levels of the tumors’ markers of CEA and CA 15-3 in a sample of patients classified in different groups according to the breast cancer.
Results: The general half age was of 49.7 although there was women’s prevalence with 46-50 years (69%). The carcinoma ductal infiltrates (IDC) it showed in incidence of 30% in the studied sample, besides 24% of family history of cancer. Also, they were significant association relationships between the distribution of the levels of CEA and CA 15-3 regarding family history and type of diagnosed tumor and of CA-15-3 regarding the age, particularly in the group 46 years they registered the highest levels.
Conclusion: The incidence of the IDC was of waiting then it is one of the types more common of cancer of he/she suckles. On the other hand, the significant differences of the levels of CEA and CA 15-3 respect to family load and tumor type is an evidence of the clinical value of the combination of both markers in the characterization of the studied patients; while, the significant variations of CA 15-3 regarding age suggest a bigger diagnostic sensibility.
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