2015, Number S1
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salud publica mex 2015; 57 (S1)
Prospective study of the link between overweight/obesity and diabetes incidence among Mexican older adults: 2001-2012
Pinto G, Beltrán-Sánchez H
Language: English
References: 23
Page: 15-21
PDF size: 273.45 Kb.
ABSTRACT
Objective. To prospectively assess the relationship between
overweight/obesity and incidence of type 2 diabetes mellitus
(T2DM) among Mexicans aged 50+, assessing effects of age,
genetic predisposition, education, physical activity, and place of
residence.
Materials and methods. The Mexican Health
and Aging Study (MHAS) was used to prospectively follow
respondents free of diabetes in 2001 who became diabetic
by 2012. Multivariate random effects logistic regression was
used to assess covariates effects on the incidence of T2DM.
Results. Obese or overweight individuals at baseline (2001)
were about 3 and 2 times, respectively, significantly more likely
to become diabetic by 2012. Genetic predisposition increases
the risk of diabetes by about three times compared to those
with no family history of diabetes.
Conclusion. Overweight/
obesity and genetic predisposition are the primary drivers
of diabetes incidence among Mexican older adults. Reducing
body weight and having access to health care may ameliorate
the disease burden of T2DM.
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