Morales-Peralta A, Covarrubias-Espinoza G, Arvizu-Amador T, Rendón-García H, Larios-Farak T, Martínez-González A

Language: Spanish
References: 15
Page: 44-48
PDF size: 489.51 Kb.

ABSTRACT

The basophilic leukemia is a rare disease in the (omitted) pediatrics. It is now recognized as a distinct entity within myeloid leukemias with specific diagnostic criteria that require molecular studies and techniques specific histopathology. An unusual case of a patient with chronic myeloid leukemia referred to the Children’s Hospital from the State of Sonora, which presents an abnormal behavior frontline management is presented. Presents with blastic transformation within the first year of diagnosis. Blasts show myeloid immunophenotype (CD33, CD13, CD117) positive characterization for CD9, CD11b, I highly suggest the basofiílica nature of the blasts. Conventional cytogenetic study reveals 2q37 deletion. Bone marrow aspirate blasts watching basophils and basophilia was reviewed. After a short period of accelerated phase clinical remission and eventually develop blast crisis.

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