2015, Number 2
<< Back
Ann Hepatol 2015; 14 (2)
The role of small heterodimer partner in hepatic lipid homeostasis
Barranco-Fragoso B, Almeda-Valdes P, Aguilar-Olivos N, Méndez-Sánchez N
Language: English
References: 7
Page: 286-287
PDF size: 62.43 Kb.
ABSTRACT
Comment:
Small heterodimer partner (SHP, NR0B2) interacts
with orphan members of the nuclear receptor
superfamily, including the constitutive androstane
receptor, retinoid receptors, thyroid hormone receptor,
and orphan receptor MB67.
REFERENCES
Seol W, Choi HS, Moore DD. An orphan nuclear hormone receptor that lacks a DNA bindingdomain and heterodimerizes with other receptors. Science 1996; 272: 1336-9.
Johansson L, Bavner A, Thomsen JS, Farnegardh M, Gustafsson JA, Treuter E. The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptors. Mol Cell Biol 2000; 20: 1124-33.
Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 2006; 126: 789-99.
Sanyal S, Kim JY, Kim HJ, Takeda J, Lee YK, Moore DD, Choi HS. Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. J Biol Chem 2002; 277: 1739-48.
Zhang Y, Hagedorn CH, Wang L. Role of nuclear receptor SHP in metabolism and cancer. Biochim Biophys Acta 2011; 1812: 893-908.
Aparicio NJ, Puchulu FE, Gagliardino JJ, et al. Circadian variation of blood-glucose, plasma-insulin and human growth-hormone levels in response to an oral glucose-load in normal subjects. Diabetes 1974; 23: 132-7.
Schlierf G, Dorow E. Diurnal patterns of triglycerides, free fatty-acids, blood-sugar, and insulin during carbohydrateinduction in man and their modification by nocturnal suppression of lipolysis. J Clin Invest 1973; 52: 732-40.
Full text