2015, Number 2
<< Back Next >>
Med Int Mex 2015; 31 (2)
Primary hypertension: evidence-based pharmacotherapy
Andrade-Castellanos CA
Language: Spanish
References: 15
Page: 191-195
PDF size: 383.95 Kb.
ABSTRACT
Hypertension is the leading cause of cardiovascular disease, affecting
approximately 1 billion individuals worldwide. The positive relationship
between blood pressure and the risk of cardiovascular disease is
strong, independent, and consistent. By reducing blood pressure, many
benefits can be seen in hypertensive patients; 50% to 60% lower risk
of stroke death and an approximately 40% to 50% lower risk of death
due to coronary artery disease. We review the evidence behind the
pharmacological strategies available in the treatment of this disease.
REFERENCES
Campos-Nonato I, Hernández-Barrera L, Rojas-Martínez R, Pedroza-Tobías A y col. Hipertensión arterial: prevalencia, diagnóstico oportuno, control y tendencias en adultos mexicanos. Salud Pública Méx 2013;55:144-150.
Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Agespecific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002;360:1903-1913.
Mancia G, Fagard R, Narkiewicz K, Redon J, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2013;34:2159-2219.
James PA, Oparil S, Carter BL, Cushman WC, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014;311:507-520.
Wright JM, Musini VM. First-line drugs for hypertension. Cochrane Database Syst Rev 2009;3:CD001841.
Musini VM, Nazer M, Bassett K, Wright JM. Blood pressurelowering efficacy of monotherapy with thiazide diuretics for primary hypertension. Cochrane Database Syst Rev 2014;5:CD003824.
van Vark LC, Bertrand M, Akkerhuis KM, Brugts JJ, et al. Angiotensin-converting enzyme inhibitors reduce mortality in hypertension: a meta-analysis of randomized clinical trials of renin-angiotensin-aldosterone system inhibitors involving 158,998 patients. Eur Heart J 2012;33:2088- 2097.
Chen N, Zhou M, Yang M, Guo J, et al. Calcium channel blockers versus other classes of drugs for hypertension. Cochrane Database Syst Rev 2010;8:CD003654.
Gupta AK, Arshad S, Poulter NR. Compliance, safety, and effectiveness of fixed-dose combinations of antihypertensive agents: a meta-analysis. Hypertension 2010;55:399-407.
Dahlöf B, Sever PS, Poulter NR, Wedel H, et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet 2005;366:895-906.
Jamerson K, Weber MA, Bakris GL, Dahlöf B, et al. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N Engl J Med 2008;359:2417- 2428.
Wu HY, Huang JW, Lin HJ, Liao WC, et al. Comparative effectiveness of renin-angiotensin system blockers and other antihypertensive drugs in patients with diabetes: systematic review and bayesian network meta-analysis. BMJ 2013;347:6008.
Wiysonge CS, Bradley HA, Volmink J, Mayosi BM, et al. Beta-blockers for hypertension. Cochrane Database Syst Rev 2012;11:CD002003.
Lip GY, Felmeden DC, Dwivedi G. Antiplatelet agents and anticoagulants for hypertension. Cochrane Database Syst Rev 2011;12:CD003186.
Sackett DL, Haynes RB, Guyatt GH. Clinical Epidemiology. A basic science for clinical medicine. 2nd ed. Boston: Little, Brown and Company, 1991.