de Oliveira MSA, Camargo VBAL, Soares MB, Lourenço C, Rocha A

Language: English
References: 18
Page: 23-28
PDF size: 297.84 Kb.

ABSTRACT

Pseudoxanthoma elasticum (PXE) is a rare inherited disorder characterized by fragmentation and calcification of elastic fibers with many systemic manifestations. The inheritance patterns can be either autosomal dominant or autosomal recessive. Typical skin lesions include yellowish papules preferentially on flexural sites, such as antecubital, popliteal, cervical, axillary, and periumbilical areas. Cardiovascular system is also involved leading to intermittent claudication, hypertension and diminished peripheral pulses. Ocular manifestations include the so-called angioid streaks. The purpose of this article was to report the clinical cases of PXE presented in the Hospital de Clínicas, Universidade Federal de Uberlândia, MG, Brazil, from January

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