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ISSN 1561-3070 (Electronic)

2014, Number 2

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Rev Cub Oftal 2014; 27 (2)

Current concepts about the meibomian gland dysfunction

Cárdenas DT, Hernández LI, Guerra AM, Cruz ID, Miranda HI, Montero DE

Language: Spanish
References: 40
Page: 264-271
PDF size: 86.16 Kb.


ABSTRACT

Scientists have been interested in the study of secretions from meibomian glands for many years. Related illnesses as cancer and posterior blepharitis have been found in the medical literature since the first half of the 20th century. However, the term “meibomian gland dysfunction” was introduced by Korb and Henríquez in 1980. There was not a set definition published in the literature until over 50 international experts participated in a workshop held for 2 years. It was there where this disorder was finally defined as a chronic diffuse anomaly occurred in these glands, which is generally characterized by obstructed terminal duct and qualitative/quantitative changes in the gland secretion. This may cause altered lachrymal film, ocular irritation symptoms, clinically apparent inflammation and ocular surface disease. In the same international workshop, it was decided to classify meibomian gland dysfunction according to the anatomical, physiopathological changes or to the severity of the disease, being the obstructive type the most generalized form. This is a frequent illness that reduces the quality of life and causes potentially serious damages for the human wellbeing.


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