2013, Number 4
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CorSalud 2013; 5 (4)
Echocardiographic assessment of left ventricular function in centenarians
Peña-Bofill V, Arjona RIA, Espronceda SK, Cabrera RI, Massip NJ
Language: Spanish
References: 34
Page: 325-333
PDF size: 565.73 Kb.
ABSTRACT
Introduction: Population aging is a global phenomenon and an achievement of mankind.
Objective: To characterize left ventricular function by echocardiography in ambulatory patients over 100 years old in Plaza de la Revolution Municipality, between September 2009 and September 2010.
Method: A descriptive cross-sectional study was carried out with 20 long-lived people, in the Department of Echocardiography of General Calixto García University Hospital, to whom echocardiography was performed to assess left ventricular function.
Results: The mean age was 102 years old, females were predominant with 15 patients (75%) and 50% had white skin color. The most prevalent coronary risk factor was hypertension (40%); diabetes mellitus type 2, dyslipidemia, and smoking followed in this order. Centenarians had preserved systolic function of the left ventricle (90%) with little tendency to supernormality, one patient had segmental contractility disorders in the underside, which corresponded to a history of myocardial infarction. Four centenarians had normal filling pattern, 11 had impaired ventricular relaxation and five pseudonormal patterns.
Conclusions: In the centenarians studied, the left ventricular systolic function as assessed by echocardiography is maintained within normal parameters, with signs of mild diastolic dysfunction.
REFERENCES
Pérez Díaz R. Estrés y longevidad. Reflexiones acer-ca del tema desde una perspectiva psicológica. GEROINFO [Internet]. 2006 [Citado 2013 Jun 10]; 1(3). Disponible en: http://www.sld.cu/galerias/pdf/sitios/gericuba/estres_y_longevidadl.pdf
Gavrilov LA, Gavrilova NS. Biodemographic study of familial determinants of human longevity. Popul-ation: An English Selection. 2001;13(1):197-222.
Beers M, Berkow R. The Merck Manual of Geriatric. Clinical Pharmacology. 3rd Edition. NJ: Merck Re-search Laboratory, 2000; p. 3-7.
Powell KR, Kaplan DI, Founder F. Resin Longevity Studies. [Citado 2013 Jun 10]. Disponible en: http://sti.srs.gov/fulltext/tr2002091/tr2002091.html
de la Osa JA. Viven en Cuba 1541 centenarios. Pe-riódico Granma. 2010 Mayo 25.
Ocampo JM, Gutiérrez J. Envejecimiento del siste-ma cardiovascular. Rev Col Cardiol. 2005;12(2):53-63.
Weyman AE. The year in echocardiography. J Am Col Cardiol. 2004;43(1):140-8.
Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for Chamber Quantification: Report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantific-ation Writing Group, Developed in Conjunction with the European Association of Echocardiogra-phy, a Branch of the European Society of Cardio-logy. J Am Soc Echocardiog. 2005;18(12):1440-63.
Cheitlin MD, Alpert JS, Armstrong WF, Aurigemma GP, Beller GA, Bierman FZ, et al. ACC/AHA Guide-lines for the Clinical Application of Echocardio-graphy. A report of the American College of Car-diology/American Heart Association Task Force on Practice Guidelines (Committee on Clinical Applic-ation of Echocardiography). Developed in collabor-ation with the American Society of Echocardio-graphy. Circulation. 1997;95(6):1686-744.
10.Gardin JM, Adams DB, Douglas PS, Feigenbaum H, Forst DH, Fraser AG, et al. American Society of Echocardiography. Recommendations for a stand-ardized report for adult transthoracic echocardio-graphy: a report from the American Society of Echocardiography's Nomenclature and Standards Committee and Task Force for a Standardized Echo-cardiography Report. J Am Soc Echocardiogr. 2002; 15(3):275-90.
11.Gottdiener J, Bednarz J, Devereux R, Gardin J, Klein A, Manning W, et al. American Society of Echocar-diography recommendations for use of echocardio-graphy in clinical trials. J Am Soc Echocardiogr. 2004;17(10):1086-119.
12.Nagueh SF, Appleton CP, Gillebert TC, Marino PN, Oh JK, Smiseth OA, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. Eur J Echocardiogr. 2009;10(2): 165-93.
13.Zapata M, Piñats F, Torres J. Relación inversa del volumen y función auricular izquierda en pacientes hipertensos sin insuficiencia cardíaca. Rev Chil Car-diol. 2009;28(1):21-30.
14.Deschle HA, Allende N, Miranda A, Lakowsky A, Sánchez Luceros D, Carbajales J, et al. Volumen de la aurícula izquierda indexada por superficie corporal en sujetos normales divididos por sexo y edad. Rev Argent Cardiol. 2010;78(1):39-42.
15.Sáez T, Suárez C, Blanco F, Gabriel R. Epidemiología de las enfermedades cardiovasculares en la pobla-ción anciana española. Rev Esp Cardiol. 1998; 51(11):864-73.
16.Abbot MH, Abbey H, Boling DR, Murphy EA. The familial component in longevity – a study of off-spring of nonagenarians: III. Intrafamilial studies. Am J Med Genet. 1978;2(2):105-20.
17.Paterno CA, Cornelio CI, Giménez JC. Asociación de factores de riesgo coronario en la ancianidad. Estu-dio AFRICA. Rev Esp Cardiol. 2006;59(6):628-31.
18.MINSAP. Anuario estadístico de Salud 2009. La Habana: Ministerio de Salud Pública. [Citado 2013 Jun 10]. Disponible en: http://files.sld.cu/bvscuba/files/2013/05/anuario-2009e3.pdf
19.Rontu R, Ojala P, Hervonen A, Goebeler S, Karhu-nen PJ, Nikkilä M, et al. Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenarians. Clin Endo-crinol (Oxf). 2006;64(3):265-70.
20.Leonetti G, Cuspidi C, Fastidio M, Lonati L, Chianca R. Arterial hypertension as a risk factor in the elderly and its treatment. J Hypertens 1992;10 (Suppl. 2):S3-7.
21.Kannel WB, Cobb J. Framingham Study: risk factors in the cohort aged 65 and older. En: Lewis B, Man-cini M, Farinaro E, editores. Prevention of cardio-vascular heart disease in the elderly. Londres: Current Medical Literatura, 1991; p. 3-18.
22.Motta L, Carnazzo G. Il Diabete nell’anziano. Atti del 958 Congresso della Societa Italiana di Medici-na Interna. Roma: Pozzi Publisher, 1994; p. 23-37.
23.Rosso D, Di Stefano F, Motta M, Carnazzo G. On diabetes in the elderly. Diabet Med. 1996;13(8): 771-2.
24.Franceschi C, Motta L, Valensin S, Rapisarda R, Franzone A, Berardelli M, et al. Do men and women follow different trajectories to reach extreme longevity? Italian Multicenter Study on Centena-rians (IMUSCE). Aging (Milano). 2000;12(2):77-84.
25.Kronmal RA, Cain KC, Ye Z, Omenn GS. Total serum cholesterol levels and mortality risk as a function of age: A report based on the Framingham data. Arch Intern Med. 1993;153(9):1065-73.
26.Foppa M, Duncan B, Rohde LE. Echocardiography based left ventricular mass estimation. How should we define hypertrophy? Cardiovasc Ultrasound [Internet]. 2005 [citado 2013 Jun 20];3:17. Dispo-nible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183230/pdf/1476-7120-3-17.pdf
27.Coca A, Gabriel R, De la Figuera M, López J, Fernán-dez R, Sagastagoitia J, et al. The impact of different echocardiographic diagnostic criteria on the preva-lence of left ventricular hypertrophy in essential hypertension: The VITAE study. J Hypertens. 1999; 17(10):1471-80.
28.Tovillas-Morán FJ, Zabaleta-del-Olmo E, Dalfó-Ba-qué A, Vilaplana-Cosculluela M, Galcerán JM, Coca A. Morbimortalidad cardiovascular y patrones geo-métricos del ventrículo izquierdo en pacientes hi-pertensos atendidos en atención primaria. Rev Esp Cardiol. 2009; 62(3):246-54.
29.Feingenbaum H, Armstrong WF. Feingenbaum Eco-cardiografía. Evaluación de las funciones sistólicas y diastólicas del ventrículo izquierdo. 6ta ed. 2005; p. 138-212.
30.Sadiq A, Choudhury M, Ali K, Mohamed E, Shetty V, Kabalkin C, et al. Echocardiographic characteristics in patients > or =100 years of age. Am J Cardiol. 2007;100(12):1792-4.
31.Sytkowsky PA, Kannel WB, D’Agostino RB. Changes in risk factors and the decline in mortality from car-diovascular disease. The Framingham Heart Study. N Eng J Med. 1990;322(23):1635-41.
32.Alves-Silva LS, Nassri EJ, Marcílio de Souza CA. Fre-cuencia de disfunción diastólica del ventrículo iz-quierdo por Doppler mitral en adultos sanos. Arq Bras Cardiol. 2009;93(4):321-6.
33.Borges A, Deschapelles E, Mendoza JL, Chacón D, Rodríguez JL, Rivas J, et al. Patrones de flujo trans-mitral en pacientes con hipertensión arterial esen-cial. Rev Cub Med Mil [Internet]. 2004 [citado 2013 Jun 20];33(1). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-65572004000100001&lng=es
34.Sánchez IF, Fong JA, Llanes OJ, Perú I. Función car-diovascular evaluada mediante ecocardiografía en ancianos hospitalizados. MEDISAN. 2011;15(4):426-32.