González MAE, Romero SAR, Serrano RG

Language: Spanish
References: 20
Page: 244-251
PDF size: 584.74 Kb.

ABSTRACT

Introduction: In the study of pulmonary atresia with intact ventricular septum, not enough attention has been paid to the dual nature of the left ventricle as a circulatory receptor, and its impact on systemic hemodynamics.
Objective: To identify, by echocardiography, the pathophysiological elements that characterize the disease and that determine its basic hemodynamic performance, influencing cardiac output and generating potential conditions for short-term prognosis.
Method: A descriptive, prospective and applied study was conducted. It included 43 patients who were referred to the William Soler Pediatric Cardiology Hospital from January 1992 to November 2011 with a diagnosis of the disease. In each subject, the profiles of eight echocardiographic variables were assessed, as well as the heart rate profile. Their level of association and mutual dependence were statistically assessed by simple regression models.
Results: There are considerable variations in heart rate, in the volume index and in the ejection fraction of the patients’ left ventricle compared with those in the re-ference control group.
Conclusions: The increased size of the atrial septal defect and the prolongation of transmitral diastasis favor left ventricular volume increment. Heart rate, the restrictive nature of the left ventricular myocardium and its ejection fraction are regulatory factors of cardiac output in this disease.

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