Basave RMN, Rangel A, Solorio MS, Chávez PE, Albarrán LH, Ortiz HP, Ortíz MS,Rangel P, Soriano CM

Language: Spanish
References: 11
Page: 61-65
PDF size: 78.23 Kb.

ABSTRACT

Purpose: Determine variations in myocardial lactate production during coronariography and coronary angioplasty. Methods: We studied 19 patients with ischemic heart disease, diagnostic catheterization was performed in 11(Group A), and in 8, angioplasty was also performed (Group B). We quantified lactate in blood from coronary sinus of all patients before and after diagnostic catheterization, and in Group B after angioplasty. Results: Lactate concentration was similar in both groups during diagnostic catheterization (p = NS), but it increased from 8.00 ± 2.00 mg dL^-1 after catheterization to 15.50 ± 10.89 mg dL^-1 postangioplasty in Group B (p < 0.005). Five patients with elective angioplasty did not show differences in lactate during the procedure, but in 3 with urgent angioplasty lactate increased from 9.67 ± 1.53 mg dL^-1 at the beginning to 18.00 ± 3.61 mg dL^-1 at the end of the diagnostic catheterization (p < 0.005), and up to 28.33 ± 3.51 mg dL^-1 postangioplasty (p < 0.005). Compared with elective, urgent angioplasty produced lactate increase at the end of the diagnostic catheterization (p < 0.05) and even more postangioplasty (p < 0.005).Conclusion: Myocardial lactate production does not modify during elective diagnostic coronariography or elective uncomplicated angioplasty, but significatively increases it in urgent angioplasty.

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