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2015, Number 1

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Rev Cubana Neurol Neurocir 2015; 5 (1)

Clinical–pathologic and neuroimaging characteristics of brain metastases

Caballero GJ, Cruz GO, Morales PI, Pérez LP, Hernández DZ, Salazar RS

Language: Spanish
References: 26
Page: 5-12
PDF size: 322.59 Kb.


ABSTRACT

Objective: To determine the clinical–pathologic and neuroimaging characteristics of brain metastases.
Methods: It was done a retrospective longitudinal descriptive study from 1.01.2012 to 1.01.2014 according to clinical, anatomopathologic and neuroimaging variables from clinical histories of patients from Luis Diaz Soto Hospital and National Institute of Oncology and Radiobiology. The distributions of frequencies were analyzed to describe the qualitative variables and for quantitative variables with medium and range. The Fisher exact test was utilized with a confidence interval of 95 %.
Results: 32 patients and 70 lesions were identified. The age average was 53.9 years. The most frequent localizations were lung (44 %), breast (22 %), colorectal (10 %) and prostate (6 %). Single lesions were predominant in 60 % of cases. Oligo–metastasis was more frequent in breast, colorectal and prostate (p=0.007). Average volume of metastasis was 8 cm3 (0.1–46 cm3). 88 % were solid lesions and 76 % were lesions with low surrounding edema. Mainly lesions were below de 5 cm3 originated in lung and breast (p=0.004), but local cerebral edema was more frequent in relation with this primary sites (p=0.000).
Conclusions: It was found a strong association between the primary organ and these variables: form of presentation, sex, number of lesions, volume and surrounding edema.


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