2014, Number 6
<< Back Next >>
salud publica mex 2014; 56 (6)
Direct medical costs of neonatal respiratory distress syndrome in two specialized public hospitals in Mexico
Martínez-Valverde S, Castro-Ríos A, Salinas-Escudero G, Villasis-Keever MA, Garduño-Espinosa J, Muñoz-Hernández O
Language: Spanish
References: 26
Page: 612-618
PDF size: 253.02 Kb.
ABSTRACT
Objective. To estimate direct medical costs (DMC) associated with treatment of Respiratory Distress Syndrome (RDS) in newborns (NB) in two specialized public hospitals in Mexico.
Materials and methods. The perspective used was health care payer. We estimated DMC associated with RDS management. The pattern of resource use was established by reviewing clinical records. Microcosting and bootstrap techniques were used to obtain the DMC. Estimated costs were reported in 2011 US dollars.
Results. Average DMC per RDS event was 14226 USD. The most significant items that account for this cost were hospitalization (38%), laboratory and diagnostic exams (18%), incubator time (10%), surfactant therapy (7%), and mechanical ventilation (7%).
Conclusion. Average DMC in NB with RDS fluctuated in relation to gestational age weight at birth and clinical complications presented by patients during their hospitalization.
REFERENCES
Goldenberg RL, Culhane JF, Lams JD, Romero R. Epidemiology and causes of preterm birth. Lancet 2008;371(9606):75-84.
Yost CC, Soll RF. Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome. The Cochrane Library 2000;(2):1-11.
Soll RF. Prophylactic natural surfactant extract for preventing morbidity and mortality in preterm infants. Cochrane Database Syst Rev 1997;4:CD000511.
Sweet D, Bevilacqua G, Carnielli V, Greisen G, Plavka R, Saugstad OD, et al. European consensus guidelines on the management of neonatal respiratory distress syndrome. J Perinat Med 2007;35(3):175-186.
López NL, Rodríguez JJ, Zavala A, Mendoza DS, Torres PC. Administración de surfactante exógeno en el tratamiento del síndrome de dificultad respiratoria neonatal, en su modalidad de rescate. Rev Mex Pediatr 1999;66(1):5-8.
Pérez JJ, Blancas O, Ramírez JM. Enfermedad de membrana hialina: mortalidad y factores de riesgo maternos y neonatales. Ginecol Obstet Mex 2006;74(7):354-359.
Fraser J, Walls M, McGuire W. Respiratory complications of preterm birth. BMJ 2004;329:962-965.
Zanardo V, Simbi AK, Francio M, Soldà G, Salvadori A, Trevisanuto D. Neonatal respiratory morbidity risk and model of delivery at term: influence of timing of caesarean delivery. Acta Paediatr 2004;93(5):643-647.
Hansen AK, Wisborg K, Uldbjerg N, Henriksen TB. Elective caesarean section and respiratory morbidity in the term and near-term neonate. Acta Obstet Gynecol Scand 2007;86(4):389-394.
Jain L, Dudell GG. Respiratory transition in infants delivered by cesarean section. Semin Perinatol 2006;30(5):296-304.
Mazzi GE. Síndrome de dificultad respiratoria en el recién nacido (SDR). Rev Soc Bol Ped 1995;34(2):68-74.
Profit J, Lee D, Zupancic JA, Papile L, Gutierrez C, Goldie SJ, et al. Clinical benefits, costs, and cost-effectiveness of neonatal intensive care in Mexico. PLoS Med 2010;7(12):e1000379. Doi:10.1371/journal.pmed.1000379
Cheung AM, Tansey CM, Tomlinson G, Díaz-Granados N, Matté A, Barr A, et al. Two years outcomes, health care use, and costs of survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med 2006;17(5):538-544.
Instituto Mexicano del Seguro Social. Guía de práctica clínica. Diagnóstico y tratamiento del síndrome de dificultad respiratoria en el recién nacido [internet document]. México: IMSS, 2009 [accessed on: December 20, 2011]. Available at: http://www.imss.gob.mx/.../GuiasClinicas/GPC_SDRRecienNacido.pdf
Banco de México. Mercado cambiario nacido [internet document]. 2011 [accessed on: December 31, 2011]. Available at: http://www.banxico.org.mx/portal-mercado-cambiario/index.html
Banco de México. Inflación 2009-2011 [internet document]. [accessed on: November 12, 2011]. Available at: http://www.banxico.org.mx/portal-inflacion/index.html
Comisión Nacional de Protección Social en Salud. Registros pagados por el Fondo de Gastos Catastróficos. México: CNPSS, 2008.
Meinert CL. Clinical trials: design, conduct and analysis. In Lilienfeld AM, ed. Monographs in epidemiology and biostatistics, vol. 8. New York: Oxford University Press, 1986:71-88.
Thomas NJ, Hollenbeak CS, Lucking SE, Willson DF. Cost-effectiveness of exogenous surfactant therapy in pediatric patients with acute hypoxemic respiratory failure. Pediatr Crit Care Med 2005;6(2):160-165.
Hospital Infantil de México Federico Gómez. Dirección de Finanzas. Cuotas de recuperación de servicios de Atención Médica 2009. México: HIMFG, 2009.
Hospital Infantil de México Federico Gómez. Dirección de Finanzas. Precios Unitarios de compra de medicamentos 2009. México: HIMFG, 2009.
Vittinghoff E, Gliddon DV, Shiboski SC, McCulloch, CE. Regression methods in biostatistics: Linear, logistic, survival, and repeated measures models. New York: Springer, 2005:157-209.
Glick H, Doshi J, Sonnad S, Polsky D. Economic evaluation in clinical trials (handbooks in health economic evaluation). New York: Oxford University Press, 2007:101.
Efron B, Tibshirani RJ. An introduction to the bootstrap. Vol. 57, Monographs on Statistics and Applied Probability. NewYork: Chapman and Hall/CRC, 1993
Zupancic JA, Richardson DK, O’Brien BJ, Schmidt B, Weinstein MC. Daily cost prediction model in neonatal intensive care. Int J Technol Assess Health Care 2003;19(2):330-338.
Neil N, Sullivan SD, Lessler DS. The economics of treatment for infants with respiratory distress syndrome. Med Decis Making 1998;18(1):44-51.