2014, Number 3
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Revista Cubana de Obstetricia y Ginecología 2014; 40 (3)
High degree endometrial stromal sarcoma
Forteza SM, Ramos AMA, Pérez TM, Almeida ADA, Corrales OD
Language: Spanish
References: 12
Page: 336-341
PDF size: 159.76 Kb.
ABSTRACT
Endometrial stromal sarcoma is a rare tumor comprising less than 1 % of gynecological malignancies. We report the case of a 16 year-old adolescent with abnormal uterine bleeding who underwent hysterectomy subtotal. At microscopy the neoplasm was composed of malignant proliferation of endometrial stromal cells. Immunohistochemical studies were positive for vimentin, desmin, CD10 and CD117.
CD10 is an immunohistochemical marker of normal endometrial stroma and of endometrial stromal neoplasms. This marker is useful in the differential diagnosis of endometrial stromal sarcoma versus uterine cellular leiomyoma or uterine leiomyosarcoma. The best treatment options are obtained with a focus multidisciplinary, in specialized centers.
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