2014, Number S2
Plasma Cell Leukemia. Case presentation
Language: Spanish
References: 11
Page:
PDF size: 29.21 Kb.
ABSTRACT
Plasma Cell Leukemia, is a rare and aggressive variant of multiple myeloma characterized by the presence in the blood circulation of plasma cells, it is classified as primary or secondary to a multiple myeloma, it represents from 2 to 4% of all cases of this disease. A female, 68 year old patient is presented with a history of low back pain, thrombocytopenia anemia, hepatosplenomegaly and 25% of plasma cells in the peripheral lamina concluding as a plasma cell leukemia.REFERENCES
Alcalde Dueñas MM, Rodríguez Matos G, Santos González MR, Escobar Carmona E. Mieloma múltiple en una forma infrecuente de debut y evolución. Presentación de caso. Gac Méd Espirituana [Internet]. 2012 [citado 12 Feb 2014]; 14(2): [aprox. 8 p.]. Disponible en: http://www.revgmespirituana.sld.cu/index.php/gme/article/viewArticle/136
Pagano L, Valentini CG, De Stefano V, Venditti A, Visani G, Petrucci MT, et al. Primary plasma cell leukemia: a retrospective multicenter study of 73 patients. Ann Oncol [Internet]. 2011 [citado 12 Mar 2014]; 22(7):1628-1635. Disponible en: http://annonc.oxfordjournals.org/content/22/7/1628.full.pdf+html
D'Arena G, Valentini CG, Pietrantuono G, Guariglia R, Martorelli MC, Mansueto A. Frontline chemotherapy with bortezomib-containing combinations improves response rate and survival in primary plasma cell leukemia: a retrospective study from Multiple Myeloma Working Party. Ann Oncol. 2012; 23: 1499–1503.
De Larrea CF, Kyle RA, Durie BG, Ludwig H, Usmani S, Vesole DH, et al. Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group. Leukemia [Internet]. 2013 [citado 12 Mar 2014]; 27(4): 780-791. Disponible en: http://www.nature.com/leu/journal/v27/n4/pdf/leu2012336a.pdf