2014, Number 3
<< Back Next >>
Rev Cub Med Mil 2014; 43 (3)
Diagnosis and treatment of epididymal tumors
Rodríguez CTL
Language: Spanish
References: 46
Page: 352-369
PDF size: 418.47 Kb.
ABSTRACT
Epididymus tumors are rare and the majority of them are benign, so there is not
much information about them in the medical literature. Reaching the final histological
diagnosis implies multiple testing and represents a challenge for the physician's
performance. The present paper made an anatomical and physiological review of the
epididymus as well as provided updating on the tumors affecting this organ in terms
of diagnosis and treatment. Literature search was made in databases Hinari, PubMed,
Medline and in Goggle from 2009 to 2013. The MeSH terms were paratesticular
tumors, intrascrotal tumors and epididymal tumors in Spanish and English. Reference
books and specialized journals were also reviewed. This paper confirmed the value of
questioning and of the detailed physical exam in order to set the topographic and
differential diagnosis of these tumors. Although ultrasound is the imaging study of
choice for initial assessment, it is often inconclusive; therefore, it is necessary to
obtain nuclear magnetic resonance images so as to have additional information. When
the clinical picture and the findings from images may indicate a benign tumor, then
fine needle aspiration cytology is a reliable option to make the final classification.
Nevertheless, if this technique is not conclusive, then there is the biopsy through
transoperative freezing, which is taken with inguinotomy, thus avoiding unnecessary
radical orchiectomies. The adjuvant treatments for malignant tumors are very
customized since they depend on the patient's age, the histological type and the
tumor staging.
REFERENCES
Álvarez Maestro M, Tur González R, Alonso Dorrego JM, de la Peña Barthel J, Martin de Serrano MN. Adenomatoid tumors of the epididymis and testicle: Report of 9 cases and bibliographic review. Arch Esp Urol [Internet]. 2009 [cited 2013 Nov 12];62(2):[about 5 p.]. Available from: http://aeurologia.com/pdfs/articulos/5907577471607-eng.pdf
Gupta A, Livingston M, Singh R, Tansey D, Solomon L. Infarcted adenomatoid tumour of epididymis: A rare case report. Case Reports in Urology [Internet]. 2013 [cited 2013 Nov 12]; Article ID 937689:[about 3 p.]. Available from: http://www.hindawi.com/crim/urology/2013/937689/
Singh Bhau k, Singh Bhau S, Singh S, Chrungoo RK. Unusual presentation of rare paratesticular tumour in a child. JK Science [Internet]. 2009 [cited 2013 Dec 17];11(3):148-9. Available from: http://www.jkscience.org/archive/vol113/14- Case%20Report%20-unusual%20para%20testicular.pdf
Rodríguez Tardido A, Guzmán Martínez-Valls PL, Miñana López B. Patología intraescrotal benigna. En: Castiñeiras Fernández J. Libro del Residente de Urología. Asociación Española de Urología. Madrid: Gráficas Marte, SL; 2007. p. 921-3.
Bizimi V, Balanika AP, Motogna- Kalokairinou M, Paianidi I, Kardamis S, Kominis C, et al. Focal, asymptomatic epididymal masses-B-mode and color Doppler sonographic evaluation. Case report. Med Ultrason. [Internet]. 2010 [cited 2013 Dec 17];12(2):[about 4 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21173947
Velazco Ruiz M, Parra Gordo ML, Pena Fernández I, Bandres Carballo B, Gonzalez Sendra FJ, Caba Cuevas M, et al. Evaluación sonográfica de la patología escrotal más frecuente. Euro Eco. [Internet]. 2010 [citado 15 Dic 2013];1(3):[aprox. 6 p.]. Disponible en: http://www.euroeco.org/vol1_num3_septb2010/pdf/49_54.pdf
Cassidy FH, Ishioka KM, McMahon CJ, Chu P, Sakamoto K, Lee KS, et al. MR imaging of scrotal tumors and pseudotumors. Radiographics [Internet]. 2010 May [cited 2013 Dec 17];30(3):[about 18 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20462987 Revista Cubana de Medicina Militar 2014;43(3):352-369 - http://scielo.sld.cu 366
Stoisa D, Parra CM, Ferrer M, Sanchez Mazzaferri F, Villavicencio RL. Cistoadenoma papilar de epidídimo: A propósito de un caso. Rev Argent Radiol [Internet]. 2012 [citado 15 Dic 2013];76(4):[aprox. 6 p.]. Disponible en: http://www.scielo.org.ar/scielo.php?pid=S1852- 99922012000400006&script=sci_arttext
Román Birmingham PI, Navarro Sebastián FJ, García González J, Romero Barriuso G, Guijarro Espadas A. Tumores paratesticulares. Descripción de nuestra casuística general a lo largo de un periodo de 25 años. Arch Esp Urol [Internet]. 2012 [citado 15 Dic 2013];65(6):[aprox. 7 p.]. Disponible en: http://www.redalyc.org/articulo.oa?id=181025863011
Rajaian S, Manipadam MT, Nair S, Kekre NS. Primary extranodal marginal zone lymphoma- Epididymis. Indian J Urol [Internet]. 2011 [cited 2013 Dec 11];27:[about 3 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22279330
Apul G, Abhishek J, Deepansh D. Can radical orchiectomy be avoided for paratesticular adenomatoid tumor? Indian J Urol [Internet]. 2011 Oct- Dec [cited 2013 Dec 11];27(4):[about 2 p.]. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263233/
Shabi Ahmad M, Nagarajan S, Koye B. Epididymal germinoma: Reality or myth? Can Urol Assoc J [Internet]. 2011 [cited 2013 Dec 17]; 5 (6): [about 3 p.]. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235185/
Vishwanath TT, Singh S, Shetty SMCC, Ajay MK. Adenomatoid tumour of the epididymis: A case report. NJR [Internet]. 2013 Jan-Jun [cited 2013 Dec 13];3(1):[about 4 p.]. Available from: http://njrnepal.org/4th%20issue%20011%20dr%20simran%20adenomatoid%20tum our.pdf
Nudell DM, Lipshultz LI. Vas deferens and seminal vesicle. In: Graham SD, Keane TE, Glenn JF, editors. Glenn's Urologic Surgery. 6th ed. Maryland: Lippincott Williams & Wilkins; 2004. p. 484.
Schlegel PN, Hardy MP, Goldstein M. Male reproductive physiology. In: Wein AJ, Kavoussi L, Novick A, Partin A, Peters C, editors. Campbell-Walsh Urology. [CD-ROM] 9th ed. Philadelphia: Saunders Elsevier; 2007.
Tanagho EA. Anatomía del aparato genitourinario. En: Tanagho EA, McAninch JW, editores. Urología General de Smith. 13 ed. México D.F: Manual Moderno; 2005. p. 1-16.
Davis CJ, Woodward PJ, Dehner LP, Jones MA, Srigley JR, Sesterhenn IA, et al. Tumours of paratesticular structures. In: Eble JN, Sauter G, Epstein JI, Sesterhenn IA, editors. Pathology and genetics of tumours of the urinary system and male genital organs. WHO. International Agency for Research on Cancer. Lyon: IARC Press; 2004. p. 267.
Amin W, Parwani AV. Adenomatoid tumor of testis. Clinical Medicine: Pathology [Internet]. 2009 [cited 2013 Dec 13];2:[about 5 p.]. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990235/
Richie JP, Steele GS. Tumors of testicular adnexa. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Craig CA, editors. Campbell-Walsh Urology. 9 th ed. [CD-ROM]. Philadelphia: Saunders Elsevier; 2007.
Dell'Atti L. Ultrasound diagnosis of unusual extratesticular mass: Case report and review of the literature. Arch Ital Urol Androl [Internet]. 2013 [cited 2013 Dec 13];85(1):[about 3 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23695405
Tsili AC, Argyropoulou MI, Giannakis D, Sofikitis N, Tsampoulas K. Conventional anddiffusion- weighted magnetic resonanse imaging findings of benign fibromatous paratesticular tumor: a case report. J Med Case Reports [Internet]. 2011 [cited 2013 Dec 14];5:[about 1 p.]. Available from: http://www.jmedicalcasereports.com/content/5/1/169
Arpali E, Tok A. A patient presenting with concurrent testis torsion and epididymal leiomyoma. Case Reports in Urology. [Internet]. 2013 Sep [cited 2013 Dec 14]; Article ID 485165:[about 2 p.]. Available from: http://www.hindawi.com/crim/urology/2013/485165/
Ito Y, Nishimoto K, Ogata K, Hasebe M, Uchida A. Epididymal leiomioma: a case report. Hinyokika Kiyo [Internet]. 2009 Oct [cited 2013 Dec 14];55(10):[about 3 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19926954
Blach O, Pollock AM, Douglas D. Smooth muscle hyperplasia of the epididymis. J Surg Case Rep [Internet]. 2011 [cited 2013 Dec 14];(10):[about 1 p.]. Available from: http://jscr.oxfordjournals.org/content/2011/10/10.full
Toutziaris C, Kampantais S, Perdikis I, Gourvas V, Laskaridis L, Gkagkalidis K, et al. Papillary cystadenoma of epididymis: Is there a need for further investigation in unilateral cases? Int Surg Case Rep [Internet]. 2013 [cited 2013 Dec 15];4(7):[about 3 p.]. Available from: http://www.sciencedirect.com/science/article/pii/S2210261213001284
Prieto Albino L. Masa testicular: tres casos clínicos. EuroEco [Internet]. 2011 [citado 15 Dic 2013];2(2):[aprox. 4 p.]. Disponible en: http://www.euroeco.org/vol2_num2_junio2011/pdf/77_80.pdf
Domes Ramón R, Vázquez Mora Y, Abreu Figueredo N, Sosa Rivera M. Valor diagnóstico del ultrasonido en las afecciones testiculares en el Hospital Provincial Docente Dr. "Antonio Luaces Iraola". MediCiego [Internet]. 2012 [citado 15 Dic 2013];18(2):[aprox. 7 p.]. Disponible en: http://bvs.sld.cu/revistas/mciego/vol18_02_12/pdf/T5.pdf
Herrero de Dios A, Calletano Ramírez L, Martin Arias M. Patología testicular y escrotal benigna. EuroEco [Internet]. 2012 [citado 20 Dic 2013];3(3):[aprox. 3 p.]. Disponible en: http://www.euroeco.org/vol3_num3_septb2012/pdf/74_76.pdf
Cruz-Garciavilla P, Vázquez D, Schroeder M, Landa M, de la Torre F. Tuberculosis escrotal: informe de un caso y revisión de la bibliografía. Rev Mex Urol [Internet]. 2011 [citado 20 Dic 2013];71(3):[aprox. 6 p.]. Disponible en: http://zl.elsevier.es/es/revista/revista-mexicana-urologia-302/tuberculosis-escrotalinforme- un-caso-revision-bibliografia-90024260-casos-clinicos-2011
Caro Lozano J, Zúñiga Carrasco IR, Reyes Bonifant G. Reporte de un caso de epididimitis tuberculosa del Hospital HGZ35 del IMSS de Cosamaloapan, Veracruz. Enf Inf Microbiol [Internet]. 2011 [citado 20 Dic 2013];31(4):[aprox. 3 p.]. Disponible en: http://www.amimc.org.mx/revista/2011/31_4/reporte.pdf Revista Cubana de Medicina Militar 2014;43(3):352-369 - http://scielo.sld.cu 368
Marrero Rodríguez H, Quintero Salcedo S, del Campo Mulet E, López Soria O, López González J. Tuberculosis genital en un adulto joven. Medisan [Internet]. 2013 [citado 20 Dic 2013];17(6):[aprox. 3 p.]. Disponible en: http://bvs.sld.cu/revistas/san/vol17_6_13/san16176.htm
Tanagho EA. Infecciones específicas del aparato genitourinario. En: Tanagho EA, McAninch JW, editores. Urología General de Smith. 13 ed. México D.F: Manual Moderno; 2005. p. 249-65.
Dellavedova T, Ponzano R, Arselan S, Lamberti A, Racca L, Tavip L, et al. Epididimitis aguda por Brucella. Comunicación de un caso. Rev Arg de Urol [Internet]. 2011 [citado 20 Dic 2013];76(4):[aprox. 3 p.]. Disponible en: http://www.revistasau.org/index.php/revista/article/viewFile/119/78
López López AI, Server Pastor G, Pérez Albacete M. Infecciones específicas: tuberculosis, VIH y brucelosis. En: Castiñeiras Fernández J. Libro del Residente de Urología. Asociación Española de Urología. Madrid: Gráficas Marte, SL; 2007. p: 663-6.
Rodríguez Collar TL, Casa de Valle Castro M, Bueno Sánchez E. Epididimitis granulomatosa inespecífica bilateral. Presentación de un caso. Rev Esp Patol [Internet]. 2012 [citado 20 Dic 2013];45(1):[aprox. 4 p.]. Disponible en: http://www.sciencedirect.com/science/article/pii/S169988551100002X
Ching- Hei Y, Kai W, Cooper TG. Why are epididymal tumours so rare? Asian J Androl [Internet]. 2012 May [cited 2013 Dic 20];14(3):[about 10 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22522502
Mechri M, Ghozzi S, Khiari R, Bougrine F, Bouziani A, BenRais N. A rare cause of scrotal mass: primary leiomiosarcoma of epididymis. BMJ Case Rep [Internet]. 2009 [cited 2013 Dic 20];[about 2 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21686870
Yuen VTH, Kirby SD, Chi Woo Y. Leiomyosarcoma of the epididymis: 2 cases and review of the literature. Can Urol Assoc J [Internet]. 2011 Dec [cited 2013 Dic 20];5(6):[about 3 p.]. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235188/
Tazi MF, Bouchikhi AA, Ahallal Y, Mellas S, Elammari J, Khallouk A, et al. Epididymal leiomyosarcoma: One case report. Case Rep Urol [Internet]. 2012 Dec [cited 2013 Dic 22]; Article ID 236320:[about 2 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22606631
Kumar R, Kapoor R, Khosla D, Kumar N, Ghoshal S, Kumar Mandal A, et al. Paratesticular rhabdomyosarcoma in young adults: A tertiary care institute experience. Indian J Urol [Internet]. 2013 Apr- Jun [cited 2013 Dec 23];29(2):[about 4 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23956511
Faure A, Diakite ML, Panait N, Chaumoitre K, Rome A, Merrot T. Paratesticular rhabdomyosarcoma in children: a scrotal emergency. Arch Pediatr [Internet]. 2012 Dec [cited 2013 Dec 23];19(12):[about 5 p.]. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289696/
Bouchikhi AA, Mellas S, Fadl Tazi M, Lahlaidi K, Kharbach Y, Benhayoune K, et al. Embrionic paratesticular rhabdomyosarcoma: a case report. J Med Case Pep [Internet]. 2013 [cited 2013 Dec 25];7:[about 3 p.]. Available from: http://www.jmedicalcasereports.com/content/7/1/93
Boulma R, Gargouri MM, Sallemi A, Chlif M, Fitouri Z, Kallel Y, et al. Paratesticular pleomorphic rhabdomyosarcoma: A report of two cases. Case Rep Urol [Internet]. 2013 [cited 2013 Dec 26];[about 4 p.]. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583059/
Pastor Navarro T, Verges Prosper A, Planelles Gómez J, Pérez Ebri ML, Llorente Domenech R, Osca García JM, et al. Paratesticular rhabdomyosarcoma: a case report. Arch Esp Urol [Internet]. 2013 Apr [citado 2013 Dic 20];66(3):[aprox. 3 p.]. Available from: http://aeurologia.com/articulo_prod.php?id_art=8223143351977
Hazariwala R, Morris Cg, Gilbert S, Algood C, Zlotecki RA. Radiotherapy for spermatic cord sarcoma. Am J Clin Oncol [Internet]. 2013 Aug [cited 2013 Dec 26];36(4):[about 3 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22772428
Aydin A, Aksoy HZ, Reis A, Ȫzdemir F. Undiferentiated carcinoma of the epididymis. Acta Clin Croat [Internet]. 2011 [cited 2013 Dec 26];50(3):[about 4 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22384778