2014, Number 11
<< Back Next >>
MediSan 2014; 18 (11)
Non traditional drugs in the treatment of patients with wounds which cure by second intention
González TJH
Language: Spanish
References: 31
Page: 1603-1610
PDF size: 102.00 Kb.
ABSTRACT
At present there are new drugs with a high effectiveness in the treatment of patients
with wounds which cure by second intention. That is why it was decided to make a
literature review on the effects, cause of prescription and use of some of these non
traditional, more modern and more effective products which are internationally
marketed; among which there were the growth factors, interleukins, collagen, quitine,
ozone, polyvinilbutilic ether, drugs for debridement, olygotherapy, the negative pressure
devices, the "intelligent" bandages, the interactive and bioactive dressings, and the cure
in humid atmosphere. Also, the use of mother cells is pointed out, the gen therapy and
the defense peptides, as greater promising possibilities for the future. These new drugs
are not used in Cuba, but if they are included to the National Health System, they would
influence in the improvement of the medical care quality in patients with dehiscent
wounds.
REFERENCES
Rodríguez R, González JH. Métodos alternativos para el tratamiento de pacientes con heridas infectadas. MEDISAN. 2011; 15(4): 503-14.
González JH, Rodríguez R, Machado M, González J, Cabrera J. Heridas. Métodos de tratamiento. MEDISAN. 2004 [citado 5 Sep 2011]; 8(1).
Schneider MR, Werner S, Paus R, Wolf E. Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology. Am J Pathol 2008; 173(1): 14-24.
Fernández J, Berlanga J, López PA, López E, Herrera LS, Yera IB, et al. Infiltración del Heberprot-P. Un tratamiento eficaz para la úlcera del pie diabético. La Habana: Elfos Scientiae; 2009. p. 1-106.
Brem H, Sheehan P, Boulton AJ. Protocol for treatment of diabetic foot ulcers. Am J Surg. 2004; 187(5A): 1S-10S.
Dantas Filho AM, Aguiar JL, Rocha LR, Azevedo IM, Ramalho E, Medeiros AC. Effects of the basic fibroblast growth factor and its anti-factor in the healing and collagen maturation of infected skin wound. Acta Cir Bras. 2007; 22(Suppl.1): 64-71.
Basu S, Kumar M, Chansuria J, Singh TB, Bhatnagar R, Shukla V. Effect of Cytomodulin-10 (TGF-ß1 analogue) on wound healing by primary intention in a murine model. Int J Surg. 2009; 7(5): 460-5.
Andrades P, Sepúlveda S, González J. Curación avanzada de heridas. Rev Chil Cir. 2004; 56(4): 396-403.
Ballesté J, Blanco J. Polvo de colágeno en la cicatrización de heridas por segunda intención. Rev Rol Enfermer. 2002; 25(12): 854.
Beato A. Tratamiento de las quemaduras de espesor parcial con quitina en polvo. Rev Cubana Med Mil. 1996; 25(1): 22-5.
Roeckl-Wiedmann I, Bennett M, Kranke P. Systematic review of hyperbaric oxygen in the management of chronic wounds. Br J Surg. 2005; 92(1): 24-32.
Díaz O, Castellanos R. Ozonoterapia en úlceras flebostáticas. Rev Cubana Cir. 2001; 40(2): 123-9.
Cuba. Ministerio de Salud Pública. Guía terapéutica. La Habana: Pueblo y Educación; 1991. p. 619-20.
Moreno JC, Galán M, Jiménez R. Tratamiento de las úlceras crónicas. Actas Dermosifiliogr. 2005; 96(3): 133-46.
Compendiun of pharmaceuticals and specialties. 31 ed. Ottawa: Canadian Pharmaceutical Association; 1996. p. 326-1501.
Moor A, Vachon D, Gould L. Proteolytic activity in wound fluids and tissues derived from chronic venous leg ulcers. Wound Rep Reg. 2009; 17: 832-9.
Mendonca DA, Papini R, Price PE. Negative-pressure wound therapy: a snapshot of the evidence. Int Wound J. 2006; 3(4): 261-71.
Roeckl-Wiedmann I, Bennett M, Kranke P. A systematic review of topical negative pressure therapy for acute and chronic wounds. Br J Surg. 2008; 95(6): 685-92.
Woo-Ram L, Ji-Hyun P, Kyung-Hyun K, Soo-Jung K, Dae-Hwan P, Mi-Hyun Ch, et al. The biological effects of topical alginate treatment in an animal model of skin wound healing. Wound Rep Reg. 2009; 17: 505–10.
Cardinal M, Eisenbud D, Armstrong D, Zelen Ch, Driver V, Attinger Ch, et al. Serial surgical debridement: A retrospective study on clinical outcomes in chronic lower extremity wounds. Wound Rep Reg. 2009; 17: 306-11.
Metcalfe AD, Ferguson MW. Bioengineering skin using mechanisms of regeneration and repair. Biomaterials 2007; 28(34): 5100-13.
Hrabchak C, Flynn L, Woodhouse KA. Biological skin substitutes for wound cover and closure. Expert Rev Med Devices. 2006; 3(3): 373-85.
Marston WA, Hanft J, Norwood P, Pollak R. Dermagraft Diabetic Foot Ulcer Study Group. The efficacy and safety of Dermagraft in improving the healing of chronic diabetic foot ulcers: results of a prospective randomized trial. Diabetes Care. 2003; 26: 1701-5.
Veves A, Falanga V, Armstrong DG, Sabolinski ML. Apligraft Diabetic Foot Ulcer Study. Graftskin, a human akin equivalent, is effective in the management of noninfected neuropathic diabetic foot ulcers: a prospective randomized multicenter clinical trial. Diabetes Care. 2001; 24: 290-5.
Metcalfe AD, Ferguson MW. Bioengineering skin using mechanisms of regeneration and repair. Biomaterials. 2007; 28(34): 5100-13.
Hrabchak C, Flynn L, Woodhouse KA. Biological skin substitutes for wound cover and closure. Expert Rev Med Devices. 2006; 3(3): 373-85.
Cicatrización de heridas crónicas refractarias aplicando células madre de médula ósea. Arch Dermatol. 2003; 139: 510-16.
Eming S, Krieg T, Davidson J. Gene Therapy and Wound Healing. Clin Dermatol. 2007; 25(1): 79-92.
Young LS, Searle PF, Onion D. Viral gene therapy strategies: from basic science to clinical application. J Pathol. 2006; 208: 299-318.
Steinstraesser L, Koehler T, Jacobsen F, Daigeler A, Goertz O, Langer S, et al. Host Defense Peptides in Wound Healing. Mol Med. 2008; 14(7-8): 528-37.