2003, Number 3
<< Back Next >>
Acta Ortop Mex 2003; 17 (3)
Highly aggressive giant cell tumor in knee. A four-cases report
Castañeda EB, López TD, Ballinas OOG, Enríquez CJA, Hernández LJL
Language: Spanish
References: 22
Page: 145-152
PDF size: 153.06 Kb.
ABSTRACT
Giant cell tumor (GCT) is one of the most controversial and unpredictable tumors in its clinical behavior. In this study, we report four cases in stage III (highly aggressive), between March 2001 and April 2002, in patients aged between 28 and 55 years. The four patients were from the male sex. In three cases, the right knees were affected and the left knee in just one case. The cases were analyzed according to their clinical behavior, 3 of them were treated through supracondylar amputation and in the other one it was applied a tumor-like-type prosthesis. None of the cases developed metastasis and all of the cases presented a good clinical evolution. We focus the discussion on the treatment of this stage according to the literature reports.
REFERENCES
Alkalay D, Kollender Y, Mozes M, Meller I: Giant cell tumors with intraarticular fracture. Acta Orthop Scand 1996; 67 (3): 291-294. 7.
Andrew GG: Tumores óseos, Editorial Médica Panamericana, 1981; 17: 249-273.
Anract P, De Pinieux G, Cottias P, Pouillart P, Forest M, TRomeno B: Malignant giant cell tumors of bone. Int Orthop 1998; 22(1): 19-26.
Bickels J, Meller I, Shmookler BM, Malawer MM: The role and biology of cryosurgery in the treatment of bone tumors. Acta Orthop Scand 1999; 70(3): 308-315.
Blackley HR, Wunder JS, Davis AM, White LM, Kandel R, Bell RS, Bell RS: Treatment of giant-cell tumors of long bones with curettage and bone grafting. J Bone Joint Surg 1999; 81(6): 811-820.
Campbell C: Cirugía Ortopédica, Editorial Panamericana. 1996; 1(1): 233-236.
Dahlin DC: Tumores óseos, 2da. Edición, Ediciones Toray Barcelona, 1980; 9: 93-108.
Dickerman JD: Interferon and giant cell tumors. Pediatrics 1999; 103(6): 1283-1286.
Enneking WF: Lesions of uncertain origin originating in bone. Musculoskeletal Tumor Surgery 1983; 2(35): 1435-1469.
Gitelis S, Wang JW, Quast M, Schajowicz F, Templeton A: Recurrence of giant-cell tumor with malignant transformation to a fibrosarcoma twenty-five years primary treatment. J Bone Joint Surg 1989; 71(5): 757-761.
Ilyas I, Younge D, Pant R, Moreau P: Lim salvage for proximal tibial tumours using a modular prosthesis. Int Orthop 2000; 24(4): 208-211. 10.
Mori Y, Tsuchiya H, Karita M, Nonomura A, Nojima T, TRomita K: Malignant transformation of a giant cell tumor 25 years after initial treatment. Clin Orthop 2000; (381): 185-191.
Nakumura K, Kusuzaki H, Murata H, Takeshita M, Hirata M, Hashiguchi S, Hirasawa Y: Ceramic endoprosthesis for aggressive giant cell tumors near the knee: eight cases followed for more than 10 years. Int Orthop 2001; 25(2): 104-106.
Ortiz-Cruz EJ, Quinn RH, Fanburg JC, Rosenberg AE, Mankin HJ: Late development of a malignant fibrous histiocytoma al the site of a giant cell tumor. Clin Orthop 1995; sep (318): 199-204.
Robbins: Patología estructural y funcional, tumores esqueléticos. Tumor de células gigantes. Editorial Panamericana, 4ª Edición. 1990: 1412-1414.
Robinson D, Lewis MM, Nevo Z, Kenan S, Einhorn TA: The Radiographic stage of giant cell tumor related to a stromal cells proliferation. Acta Orthop Scand 1997; 68(3): 294-297.
Sakkers RJ, van der Heul R.O, KRoon HM, Taminiau AH, Hogendoorn PC: Late malignant transformation of a benign giant-cell tumor of bone. J Bone Joint Surg 1997; 79(2): 259-262.
Soto MC, Escandón S, Soto JD: Experiencia en el tratamiento del tumor de células gigantes con criocirugía. (1977-1987). http//www. en Colombia. Con/orto 4290-tumor 12.htm.: 1-12.
Spitale LS, Piccinni DJ: Tumor de células gigantes de rótula. Comunicación No.019 II Congreso Virtual Hispanoamericano de Anatomía Patológica. 1998; 1-9.
Tsuchiya H, Tomita K, Shinokawa Y, Minematsu K, Katsuo S: The Ilizarov method in the management of giant-cell tumours of the proximal tibia. J Bone Joint Surg 1996; 78(2): 246-211.
Weiner SD, Scarborough M, Vander Griend RA: Resection Arthrodesis of the knee with an intercalary allograft. J Bone Joint Surg 1996; 78(2): 185-92.
Wold, McLeod, Sim y Unni: Atlas of Orthopedic Pathology. Editorial W.B. Saunders Company. 1990; 33: 198-203.