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2014, Number 2

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Rev Cubana Estomatol 2014; 51 (2)

General aspects of regenerative medicine in Dentistry

Morales ND

Language: Spanish
References: 57
Page: 206-223
PDF size: 155.15 Kb.


ABSTRACT

Introduction: the current revival and development of regenerative medicine and its wide range of therapeutic possibilities in dentistry is a topic of growing interest.
Objective: carry out a bibliographic review about the general aspects of regenerative medicine in dentistry.
Methods: a bibliographic review was performed which covered the period April-May 2013. An evaluation was conducted of high impact journals from the Web of Sciences (36 journals) and 3 Cuban journals. Databases from reference systems such as MEDLINE, PubMed and Scielo were consulted with the aid of search terms like "regenerative medicine dentistry", "stem cells", "tissue engineering" and their Spanish counterparts. The review included papers in English and Spanish, and publications from the last five years. Only one paper had been published before that period. Of the 120 papers obtained, the reviewers selected the 56 which approached the study topic in a more comprehensive manner. One book was reviewed.
Results: an analysis of the representativeness of papers in the scientific journals where they were published showed that 7,02 % corresponded to the Cuban Journal of Hematology, Immunology and Hemotherapy, a sign of the importance awarded to the subject in the country. The remaining papers were scattered among the other journals.
Conclusions: knowledge about the theoretical foundations of regenerative medicine as applied to the substitution of healthy cells for cells damaged by various processes in certain tissues, justifies its potential use in dentistry, based on the correct application of the concepts of regenerative medicine, stem cells (including its action mechanisms, types, sources), soluble factors, gene transplantation and tissue engineering.


REFERENCES

  1. Scheller EL, Krebsbach PH, Kohn DH. Tissue engineering: state of the art in oral rehabilitation. J Oral Rehabil. 2009;36(5):368-89.

  2. Niemansburg S, van Delden JJM, Bredenoord AL. Regenerative medicine interventions for orthopedic disorders: ethical issues in the traslation into patients. Regen. Med. 2013;8(1):65-73.

  3. Want AJ, Nienow AW, Hewitt CJ, Coopman K. Large'scale expansion and explotation of pluripotent stencella for regenerative medicine purposes: beyond the T flask. Regen. Med. 2012;7(1):71-84.

  4. Pérez Borrego A, Domínguez Rodríguez L, Ilisástigui Ortueta ZT. De la terapia celular a la regeneración periodontal. Rev Haban Cienc Méd [Internet]. 2009 [citado 1 abril 2013];8(2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1729 - 519X2009000200007&lng=es&nrm=iso&tlng=es

  5. Hernández Ramírez P. Medicina regenerativa y aplicaciones de las células madre: una nueva revolución en medicina. Rev Cubana Med [Internet]. 2011 [citado 1 abril 2013];50(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034 - 75232011000400001&lng=es&nrm=iso&tlng=es

  6. Hernández Ramírez P. Medicina regenerativa y células madre. Mecanismos de acción de las células madre adultas. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2009 [citado 1 abril 2013];25(1). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864- 02892009000100002&lng=es&nrm=iso&tlng=es

  7. Cruz Tamayo F. ¡Qué no se detenga la Ola Regenerativa! Rev Cubana Hematol Inmunol Hemoter [Internet]. 2013 [citado 1 abril 2013];29(1). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864- 02892013000100001&lng=es&nrm=iso&tlng=es

  8. Rodríguez-Lozano FJ. Mesenchymal dental stemcells in regenerativedentistry. Med Oral Patol Oral Cir Bucal. 2012;17(6):e106-27.

  9. Hernández Ramírez P. Medicina regenerativa y enfermedades renales. En: Arce Bustabad S. Trasplante renal y enfermedad renal crónica. Sistema de leyes integradoras. La Habana: Editorial de Ciencias Médicas; 2009.

  10. Kim SH. Gene expression profile in mesenchymal stem cells derived from dental tissues and bone marrow. J Periodontal Implant Sci. 2011;41(4):192-200.

  11. Martino S, D'Angelo F, Armentano I, Kenny JM, Orlacchio A. Stem cellbiomaterial interactions for regenerative medicine. Biotechnol Adv. 2012;30(1):338-51.

  12. Patel DM, Shah J, Srivastava AS. Therapeutic Potential of Mesenchymal Stem Cells in Regenerative Medicine. Stem Cells Int. 2013; 2013:4962-18.

  13. Estrela C, Gonçalves de Alencar AH, Kitten GT, Franco Vencio E, Gava E. Mesenchymal stem cells in the dental tissues: perspectives for tissue regeneration. Braz. Dent. J. 2011;22(2):91-8.

  14. Hosseinkhani M, Shirazi R, Rajaei F, Mahmoudi M, Mohammadi N, Abbasi M. Engineering of the Embryonic and Adult Stem Cell Niches. Iran Red Crescent Med J. 2013;15(2):83-92.

  15. Rizk A, Rabie BM. Electroporation for Transfection and Differentiation of Dental Pulp Stem Cells. Biores Open Access. 2013;2(2):155-62.

  16. Bressan E, Ferroni L, Gardin C, Pinton P, Stellini E, Botticelli D, et al. Donor Age-Related Biological Properties of Human Dental Pulp Stem Cells Change in Nanostructured Scaffolds. PLoS One. 2012;7(11):e4914-6.

  17. Dado D, Sagi M, Levenberg S, Zemel A. Mechanical control of stem cell differentiation. Regen. Med. 2012;7(1):101-16.

  18. Srijaya TC, Pradeep PJ, Zain RB, Musa S, Kasim NHA, Govindasamy V. The Promise of Human Induced Pluripotent Stem Cells in Dental Research. Stem Cells Int. 2012;2012:4238-68.

  19. Hazeltine LB, Selekman JA, Palecek SP. Engineering the human pluripotent stem cell microenvironment to direct cell fate. Biotechnol Adv. 2013. doi: 10.1016/j.biotechadv.2013.03.002.

  20. Railand S, Salekdeh GH, Krijgsveld J. Defining pluripotent stem cells through quantitative proteomic analysis. Expert Rev. Proteomics 2011;8(1):29-42.

  21. Boyd A, Fairchild PJ. Approaches for inmunological tolerance induction to stem cell-derived cell replacement therapies. Expert Rev. Proteomics 2010;6(3):435-48.

  22. Gu E, Chen W-Y, Gu J, BurridgeP, Wu JC. Molecular Imaging of Stem Cells: Tracking Survival, Biodistribution, Tumorigenicity and Immunogenicity. Theranostics. 2012;2(4):335-45.

  23. Kooreman NG, Wu JC. Tumorigenicity of pluripotent stem cells: biological insights from molecular imaging. J R Soc. 2010;7(6):S753-63.

  24. Socarrás-Ferrer BB, del Valle-Pérez LO, de la Cuétara-Bernal K, Marsán-Súarez V, Sánchez Segura M, Macías-Abraham C. Células madre mesenquimales: aspectos relevantes y aplicación clínica en la medicina. Rev Cubana Hematol Inmunol Hemoter [Internet] 2013 [citado 1 abril 2013];29(1). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864- 02892013000100003&lng=es&nrm=iso&tlng=es

  25. Yamada Y, Fujimoto A, Ito A, Yoshimi R, Ueda M. Cluster analysis and gene expression profiles: A cDNA microarray system-based comparison between human dental pulp stem cells (hDPSCs) and human mesenchymal stem cells (hMSCs) for tissue engineering cell therapy. Biomaterials 2006;27 (20):3766-81.

  26. Faça VM. Human mesenchimal stromal cell proteomics: contribution for identification of new markers and targets for medicine intervention. Expert Rev Proteomics. 2012;9(2):217-30.

  27. Casado-Díaz A, Pérez GD, Quesada-Gómez JM. Stem Cell Research and Molecular Markers in Medicine. Comprehensive Biotechnology (SecondEdition); 5:455-66.

  28. Ma L, Makino Y, Yamaza H, Akiyama K, Hoshino Y, Song G, et al. Cryopreserved dental pulp tissues of exfoliated deciduous teeth is a feasible stem cell resource for regenerative medicine. PLoS One. 2012;7(12):e517-77.

  29. Tobita M, Orbay H, Mizuno H. Adipose-derived Stem Cells: Current Findings and Future Perspectives. Discov Med 2011;11(57):160-70.

  30. Egusa H, Sonoyama W, Nishimura M, Atsuta I, Akiyama K. Stem cells in dentistry Part I: Stem cell sources. J Prosthodont Res. 2012;56(3):151-65.

  31. Bakopoulou A, Leyhausen G, Volk J, Tsiftsoglou A, Garefis P, Koidis P, et al. Comparative analysis of in vitro osteo/odontogenic differentiation potential of human dental pulp stem cells (DPSCs) and stem cells from the apical papilla (SCAP). Arch Oral Biol. 2011;56(7):709-21.

  32. Guzmán-Uribe D, Alvarado Estrada KN, PozosGuillén AJ, Martín Pérez S, Rosales Ibáñez R. Development of A Three-Dimensional Tissue Construct from Dental Human Ectomesenchymal Stem Cells: In Vitro and In Vivo Study. Open Dent J. 2012;6:226-34.

  33. Lizier NF. Scaling-Up of Dental Pulp Stem Cells Isolated from Multiple Niches. PLoS One. 2012;7(6):e39-885.

  34. Nakamura S, Yamada Y, Katagiri W, Sugito T, Ito K, Ueda M. Stem Cell Proliferation Pathways Comparison between Human Exfoliated Deciduous Teeth and Dental Pulp Stem Cells by Gene Expression Profile from Promising Dental Pulp. J Endod. 2009;35(11):1536-42.

  35. SeongSik K. Differentiation and characteristics of undifferentiated esenchymal stem cells originating from adult premolar periodontal ligaments. Korean J Orthod. 2012;42(6):30717.

  36. Choi S, Cho T-J, Kwon S-K, Lee G, Cho J. Chondrogenesis of periodontal ligament stem cells by transforming growth factor-3 and bone morphogenetic protein-6 in a normal healthy impacted third molar. Int J Oral Sci. 2013;5(1):713.

  37. Honda MJ, Imaizumic M, Suzukic H, Ohshimac S, Tsuchiya S, Satomura K. Stem cells isolated from human dental follicles have osteogenic potential. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;111(6):700-8.

  38. Broccaioli E, Niada S, Rasperini G, Ferreira LM, Arrigoni E, Yenagi V, et al. Mesenchymal Stem Cells from Bichat's Fat Pad: In Vitro Comparison with Adipose- Derived Stem Cells from Subcutaneous Tissue. Biores Open Access. 2013;2(2):107- 17.

  39. Sujesh M, Rangarajan V, Kumar R, Kumar GS. Stem Cell Mediated Tooth Regeneration: New Vistas in Dentistry. J Indian Prosthodont Soc. 2012;12(1):17.

  40. Hernández Ramírez P. La mucosa nasal como vía y fuente para la medicina regenerativa. Rev Cubana Hematol Inmunol Hemoter [Internet] 2011 [citado 1 abril 2013];27(3). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864 - 02892011000300005&lng=es&nrm=iso&tlng=es

  41. Marot D, Knezevic M, Novakovic GV. Bone tissue engineering with human stem cells. Stem Cell Res Ther. 2010;1:10.

  42. Kitada M, Wakao S, Dezawa M. Muse cells and induced pluripotent stem cell: implication of the elite model. Cell Mol Life Sci. 2012;69(22):373-950.

  43. Egusa H, Sonoyama W, Nishimura M, Atsuta I, Akiyama K. Stem cells in dentistry Part II: Clinical applications. J Prosthodont Res. 2012;56(4):229-48.

  44. Soomekh DJ. Current Concepts for the Use of Platelet-Rich Plasma in the Foot and Ankle. Clin Podiatr Med Surg. 2011;28(1):155-70.

  45. Wua C-C. Regenerative potentials of platelet-rich plasma enhanced by collagen in retrieving pro-inflammatory cytokine-inhibited chondrogenesis. Biomaterials 2011;32(25):5847-54.

  46. Zhang S, Mao T, Chen F. Influence of platelet-rich plasma on ectopic bone formation of bone marrow stromal cells in porous coral. Int J Oral Maxillofac Surg. 2011;40(9):961-5.

  47. Bi L, Cheng W, Fan H, Pei G. Reconstruction of goat tibial defects using an injectable tricalcium phosphate/chitosan in combination with autologous plateletrich plasma. Biomaterials 2010;31(12):3201-11.

  48. Carvalho MD, Suaid FF, Santamaria MP, Casati MZ, Nociti FH, Sallum AW, et al. Platelet-rich plasma plus bioactive glass in the treatment of intra-bony defects: a study in dogs. J. Appl. Oral Sci. 2011;19(1):82-9.

  49. Pallua N, Woltera T, Markowicza M. Platelet-rich plasma in burns. Burns 2010;36(1):4-8.

  50. Kim BK, Kim SG, Kim SY, Lim SC, Kim YK. A comparison of bone generation capability in rabbits using tooth ash and plaster of Paris with platelet-rich plasma or fibrin sealant. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110(3):e8-14.

  51. Lee JY, Nam H, Park YJ, Lee SJ, Chung CP, Han SB, et al. The effects of platelet-rich plasma derived from human umbilical cord blood on the osteogenic differentiation of human dental stem cells. In vitro Cell Dev Biol Anim. 2011;47(2):157-64.

  52. Del Fabbro M, Boggian C, Taschieri S. Immediate Implant Placement Into Fresh Extraction Sites With Chronic Periapical Pathologic Features Combined With Plasma Rich in Growth Factors: Preliminary Results of Single-Cohort Study. J Oral Maxillofac Surg 2009;67(11):2476-84.

  53. Anitua E, Sánchez M, Orivea G. Potential of endogenous regenerative technology for in situ regenerative medicine. Adv Drug Deliv Rev. 2010;62(7-8):741-52.

  54. Anitua E, Alkhraisat MH, Orive G. Perspectives and challenges in regenerative medicine using plasma rich in growth factors. J Control Release. 2012;157(1):29-38.

  55. Zhanga L, Wanga P, Meib S, Lic C, Caia C, Dinga Y. In vivo alveolar bone regeneration by bone marrow stem cells/fibrin glue composition. Arch Oral Biol. 2012;57(3):238-44.

  56. Ward BB, Brown SE, Krebsbach PH. Bioengineering strategies for regeneration of craniofacial bone: a review of emerging technologies. Oral Dis. 2010;16:709-16.

  57. Chackartchi T, Iezzi G, Goldstein M, Klinger A, Soskolne A, and Piattelli A, et al. Sinus floor augmentation using large (12 mm) or small (0.251 mm) bovine bone mineral particles: a prospective, intraindividual controlled clinical, microcomputerized tomography and histomorphometric study. Clin Oral Implants Res. 2011;22(5):473-80.




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