2014, Number 2
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Rev Cub Med Mil 2014; 43 (2)
Multimodal analgesia with ketamine, dipyrone and tramadol association in emergency surgery
Guzmán MJK
Language: Spanish
References: 17
Page: 140-147
PDF size: 89.37 Kb.
ABSTRACT
Introduction: the postoperative pain is frequent in the patients with affections that
require urgency surgery. Its satisfactory treatment constitute one of the most
important challenges that we face today.
Objective: to compare multimodal analgesia by associating drugs as dipyrone,
tramadol, and ketamine with tramadol-dipyrone therapy in patient emergency
surgeries.
Methods: a randomized prospective, comparative, cross-sectional study was
conducted in 100 patients. They were distributed into two groups of 50 each: Group I
(control group) had dipyrone 1.2 g plus 100 mg tramadol, diluted in sodium chloride
0.9 %, 200 mL in 20 min intravenously; group II (study group) had dipyrone 1.2 g
plus 100 mg tramadol, diluted in sodium chloride 0.9 %, 200 mL in 20 min
intravenously. They also received a bolus of ketamine 0.3 mg/kg of patient body
weight, followed by continuous infusion of this drug to an infusion rate of 0.8 mg / kg
/ h to the end of the surgery.
Results: the pain intensity was smaller in the study group, thus less rescue analgesia
was used, but subjects in the group control that 90 % of the cases needed rescue
analgesia. Side effects were nausea and vomiting in group I, and dizziness in group
II. No complications occurred in either group..
Conclusions: multimodal analgesia with the association of dipyrone, tramadol, and
ketamine turns out to be a superior analgesic method in comparison to dipyronetramadol
analgesia for controlling postoperative pain in patient emergency surgeries.
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