medigraphic.com

2005, Number 4

<< Back Next >>

Vet Mex 2005; 36 (4)

Effect of estradiol on the chick embryo tectum opticum and its interactions with forebrain resection

Martínez MA, Mendoza H, Aguilar A, Díaz MSY

Language: English/Spanish
References: 30
Page: 381-394
PDF size: 552.20 Kb.


ABSTRACT

Sexual steroid hormones have effects on the growth, maturation, differentiation and functionality of glial as well as on the neuronal type nerve cells, even in areas unassociated with reproduction, stimulating the formation of synapsis, the synthesis and release of neurotransmitters and growth factors. In addition, they may exert beneficial neuroprotective type effects, such as in cases of Alzheimer´s disease in women. This study is about the effect of estradiol on the maturation of the laminated structure of the optic tectum male and female normal chick embryos submitted to experiment on encephalectomy and transplant of the pituitary primordium, by measuring the gray and superficial fibrous, central gray, central albo, gray and periventricular fibrous strata slices, stained by using the Golgi-Cox method. The results showed significant increases in the majority of the strata of both male and female embryos in comparison to the intact group treated with estradiol. It was also seen that pituitary sectomized animals slowed down the recovery of the thickness of the gray and superficial fibrous strata of males and females. These data suggest that estradiol treatment induces the formation and maturation of cellular elements in the tectum opticum lamination of chick embryos, in both males and females, and that the effect is greater when the tectal structure is intact.


REFERENCES

  1. Jung-Testas I, Baulieu EE. Steroid hormone receptors and steroid action in rat glial cells of the central and peripheral nervous system. J Steroid Biochem Mol Biol 1998; 65: 243-251.

  2. McEwen BS, Alves SE, Bulloch K, Weiland NG. Ovarian steroids and the brain: implications for cognition and aging. Neurology 1997; 48:S8-15.

  3. Alonso-Solis R, Abreu P, Lopez-Coviella I. Gonadal steroid of neuroendocrine transduction: a transynaptic view. Cell Mol Neurobiol 1996; 6: 357-382.

  4. Bi R, Broutman G, Foy MR, Thomson RF, Braudy M. The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen hippocampus. Proc Natl Acad Sci 2000; 97:3602-3607.

  5. Honda K, Sawada H, Kihara T, Urushitani M, Nakamizo T, Akaile A, et al. Phosphatidylnositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons. J Neurosci Res 2000; 60:321-327.

  6. Singh M, Sétáló G, Guan S, Warren M, Toran-Allerand CD. Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways. J. Neurosci 1999; 844:153-165.

  7. Miller DB, Ali SP, O’Callaghan JP. Laws SC. The impact of gender and estrogen on striatal dopaminergic neurotoxicity. Ann NY Acad Sci 1998; 844: 153-165.

  8. Sudo S, Wen TC, Desaki J, Matsuda S, Tanaka J, Arai T, et al. M. ß-estradiol protects hippocampal CA1 neurons against transient forebrain ischemia in gerbil. Neurosci Res 1997; 29: 345-354.

  9. Toran-Allerand CD, Ellis L, Pffeninger KH. Estrogen and insulin synergism in neurite growth enhancement in vitro: mediation of steroids effects by interactions with growth factors? Brain Res 1988; 469:87-100.

  10. Yamagata M, Herman JP, Sanes JR. Lamina-specific expression of adhesion molecules in developing chick optic tectum. J Neurosci 1995; 15: 4556-4571.

  11. Gasc, J. M. Autoradiographic studies of steroid receptor sites in embryonic tissues. J Histochem Cytochem 1981; 29: 181-189.

  12. Shin DH, Lee E, Cho SS. Glial cells in the chicken optic tectum. Brain Res 2003; 962:221-225.

  13. Fugo NW, Butcher RL. Effects of prolonged estrous cycles on reproduction in aged rats. Fertil Steril 1971; 22:98-101.

  14. Glaser Am, Van der Loos H. Analysis of thick brain sections by obverse-reverse computer microscopy: application of a new, high clarity Golgi-Nissl stain J Neurosci Methods 1981; 4:117-125.

  15. Diaz-Cintra S, Cintra L, Kemper T, Resnick O, Morgane PJ. Nucleus raphe dorsalis: A morphometric Golgi study in rats of three age groups. Brain Res 1981; 207:1-16.

  16. Scicolone G, Pereyra-Alonso S, Brusco A, Saavedra JP, Flores V. Development of the laminated pattern of the chick tectum opticum. Int J Dev Neurosci 1995; 8:845-858.

  17. Garcia-Segura LM, Dueñas M, Busiguina S, Naftolin F, Chowen JA. Gonadal hormone regulation of neuronal-glial interactions in the developing neuroendocrine hypothalamus. J Steroid Biochem Mol Biol 1995; 53: 293- 298.

  18. Quesada A, Etgen AM. Insuline-like growth factor-I regulation of α (I)-adrenergic receptor signaling is estradiol dependent in the preoptic area and hypothalamus of female rats. Endocrinology 2001; 142:599-607.

  19. Cardona-Gomez GP, Mendez P, DonCarlos LL, Azcoitias I, Garcia-Segura LM. Interactions of estrogens and insulin-like growth factor-I in the brain: implications for neuroprotection. Brain Res Rev 2001; 37:320-334.

  20. Cardona-Gomez GP, Mendez P, DonCarlos LL, Azcoitias I, Garcia-Segura LM. Interactions of estrogens and insuline-like growth factor-I in the brain: molecular mechanisms and functional implications. Steroid Biochem Mol Biol 2003; 83:211-217.

  21. Azcoitia I, Sierra A, Garcia-Segura LM. Neuroprotective effects of estradiol in the adult rat hippocampus: interaction with insulin-like growth factor-I signaling. J Neurosci Res 1999; 58:815-822.

  22. Dueñas M, Torres-Aleman I, Naftolin F, Garcia-Segura LM. Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation. Neuroscience 1996; 74:531-539.

  23. Garcia-Segura LM, Dueñas M, Fernandez-Galaz MC, Chowen JA, Argente J, Naftolin F, et al. Interaction of the signalling pathways of insulin-like growth factor-I and sex steroids in the neuroendocrine hypothalamus. Horm Res 1996; 46: 160-164.

  24. Wooley CS. Estrogen-mediated structural and functional synaptic plasticity in the female rat hippocampus. Horm Behav 1998; 34: 140-148.

  25. Beyer C, Raab H. Nongenomic effects of estrogen: embryonic mouse midbrain neurons respond with a rapid release of calcium from intracellular stores. Eur J Neurosci 1998; 10: 255-262.

  26. Murphy DD, Cole NB, Segal M. Brain derived neurotrophic factor mediates estradiol induced dendritic spine formation in hippocampal neurons. Proc Natl Acad Sci USA 1998; 95: 11412-11427.

  27. Yankova M, Hart SA, Wolley S. Estrogen increases synaptic connectivity between single presynaptic inputs and multiple postsynaptic CA1 pyramidal cells: A serial electron-microcopic study. Proc Natl Acad Sci USA 2001; 98:3525-3550.

  28. Guennoum R, Gase JM. Evidence of a functional aromatase system in the pituitary gland of the chick embryo in vitro. Endocrinol 1988; 188:229-232

  29. Yasuda Y, Fugita S. Distribution of MAP1A, MAP1B and MAP2A&B during layer formation in the optic tectum of developing chick embryos. Cell Tiss Res 2003; 314:315-324.

  30. Hutchinson JB. Gender-specific steroid metabolism in neural differentiation. Cell Mol Neurobiol 1997; 17: 603-666.




2020     |     www.medigraphic.com