Sánchez GJ, García ERM

Language: Spanish
References: 17
Page: 229-234
PDF size: 142.78 Kb.

ABSTRACT

Background: Blood transfusion is, in itself, a relatively safe procedure today; however, it is not without complications, being one of them the formation of irregular antibodies, a phenomenon known as «alloimmunization». Material and methods: In order to determine the incidence and prevalence of this phenomenon, a descriptive and cross-sectional study in patients who received surgical care in the period from February 15 to May 15, 2010 at the Hospital de Cardiología, Centro Médico Nacional Siglo XXI (IMSS) was performed. Informed consent was obtained for the deliberate search in plasma samples of irregular antibodies using two conventional laboratory techniques in immunohematology (saline/Coombs and albumin 22%) 6 times at predetermined intervals. The corresponding findings were recorded for statistical analysis. Results: 218 patients were included; 20 irregular antibodies were distributed among 12 of them: 9 with presence of them from the beginning of the study and 3 who developed them as a result of the transfusions. 50% (10) of the antibodies correspond to Rh blood system, the anti-E being the most frequent (seven times). Conclusions: The incidence and prevalence are similar to those reported in patients with transfusion-dependent chronic diseases.

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