2014, Number 4
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Rev Mex Patol Clin Med Lab 2014; 61 (4)
Profile of risk for the coronary atherosclerotic disease in asymptomatic young adults
Sorroza RNA, Jines JHE, Valdés RYC, Polo VJC, Marcel EA
Language: Spanish
References: 28
Page: 211-219
PDF size: 298.80 Kb.
ABSTRACT
Multiple epidemic studies demonstrate that, the coronary atherosclerotic disease (CAD) presents a high prevalence and a strong association between the CAD and the abdominal obesity. Our objective work was, to determine the presence of abdominal obesity, as factor of risk for CAD in asymptomatic young adults. In the Clinical Laboratory «Dayana» of the Paschal Parish, City of Guayaquil was carried out a descriptive observational traverse study of asymptomatic young adults of both sexes and 30 to 45 years that previously had given the consent to participate. The blood pressure (BP) and the indirect indicators of obesity, index of the body mass (IBM), circumference of the waist (CW), (WHI) waist/height ratio and, the levels in serum of the triglycerides (TG), total cholesterol (CT), cholesterol-lipoprotein of high density (C-HDL) they were measured by enzymatic methods; while, for C-LDL the formula of Friedewald was used, when the [TG] ≥ 400 mg/dL and, the family pathological antecedents (FPA) and the habits and non healthy lifestyles, were those declared by each participant. For the statistical analysis of the studied variables the software SPSS version was used 21. In the results it was significant association (p ‹ 0.05) between the probability of the presence of the SM and the distribution of values of risk of the variables: IBM, CW, IWS, c-LDL and Chol. On the other hand, the statistical comparison of the variables with values of risk versus the rest, demonstrated a significant correlation (p ‹ 0.05) or (p ‹ 0.01). This suggests a high potential risk for cardio-metabolic syndrome (CMS or/and CAD) of the participants in the study.
REFERENCES
Nagata M, Ninomiya T, Doi Y, Hata J, Ikeda F, Mukai N et al. Temporal trends in sudden unexpected death in a general population: the Hisayama study. Am Heart J. 2013; 165 (6): 932-938.
Executive summary: Heart Disease and Stroke statistics-2010 Update. A report from the American Heart Association. Circulation. 2010; 121: 948-954.
Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (INTERHEART STUDY): case-control study. Lancet. 2004; 364: 937-952. Disponible: http://doi.org/d557
World Health Organization. Obesity: preventing and managing the global epidemic. Report of the WHO Consultation. http://whqlibdoc.who.int/trs/WHO_TRS_894
Mazón-Ramos P. Riesgo cardiovascular en el siglo XXI. Cómo detectarlo en prevención primaria. Cómo controlarlo en prevención secundaria. Rev Esp Cardiol. 2012; 65 (Supl 2): 3-9.
Lobos Bejarano JM, Brotons Cuixart C. Factores de riesgo cardiovascular y atención primaria. Evaluación e intervención. Atención Primaria. 2011; 12 (43): 668-677. Disponible en: www.elsevier.es/ap
López-Jiménez F, Cortés-Bergoderi M. Obesidad y corazón. Rev Esp Cardiol. 2011; 64 (2): 140-9. 2.
Catenacci VA, Hill JO, Wyatt RH. The obesity epidemic. Clin Chest Med. 2009; 30: 415-444.
Haslam DW, James WP. Obesity. Lancet. 2005; 366: 1197-209.
Manson JE, Colditz GA. A prospective study of obesity and risk of coronary heart disease in women. N Engl J Med. 1990; 322: 882-889.
Manson JE, Willet WC, Stampfer MJ, Colditz GA, Hunter DJ. Body weight and mortality among women. N Engl J Med. 1995; 333: 677-685.
Carrasco F, Galgani JE, Reyes M. Síndrome de resistencia a la insulina. Estudio y manejo. Rev Med Clin Condes. 2013; 24 (5): 827-837.
González-Chávez A, Amansio-Chassin O, Isla-Andrade S, Revilla-Monsalve C, Hernández M, Lara- Esqueda A et al. Factores de riesgo cardiovascular asociados a obesidad abdominal en adultos aparentemente sanos. Rev Med Inst Mex Seguro Soc. 2008; 46 (3): 273-279.
Després JP, Lemieux I, Bergeron J, Pibarot P, Mathieu P, Larose E, Rodés-Cabau J et al. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol. 2008; 28 (6): 1039-1049.
The Expert Panel. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection. Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Final Report. Circulation. 2002; 106: 3143-3421.
Zugasti MA, Moreno BE. Obesidad como factor de riesgo cardiovascular. Hipertensión y Riesgo Vascular. 2005; 22 (1): 32-36.
Onat A, Uyarel H, Hergen G, Karabulut A, Albayrak S, Can G. Determinants and definition of abdominal obesity as related to risk of diabetes, metabolic syndrome and coronary disease in Turkish men: a prospective cohort study. Atherosclerosis. 2007; 191 (1): 182-190.
Wang Z, Nakayama T. Inflammation, a link between obesity and cardiovascular disease. Mediators Inflamm. 2010; 2010: 535918. Available in: http://dx,doi.org/10.1155
Phillips LK, Prins JB. The link between abdominal obesity and the metabolic syndrome. Curr Hypertens Rep. 2008; 10 (2): 156-164.
Martínez RG, Marin IA, Cía GP, Gálvez VAC, Bergareche IA, Gelado JC. Utilidad del perímetro abdominal como método de cribaje del síndrome metabólico en personas con hipertensión arterial. Rev Esp Salud Pública. 2010; 84: 215-222.
Siavash M, Sadeghi M, Salarifar F, Amini M, Shojaee-Moradie F. Comparison of body mass index and waist/height ratio in predicting definite coronary artery disease. Ann Nutr Metab. 2008; 53 (3-4): 162-166.
Romero-Velarde E, Vásquez-Garibay EM, Álvarez-Román YA, Fonseca-Reyes S, Casillas-Toral E, Troyo-Sanromán R. Circunferencia de cintura y su asociación con factores de riesgo cardiovascular en niños y adolescentes con obesidad. Bol Med Hosp Infant Mex 2013; 70 (5): 358-363. Disponible en: www.medigraphic.org.mx.
Lamego R, Perim B, Mill G. Asociación entre razón cintura estatura e hipertensión y síndrome metabólico: Estudio de base poblacional. Sociedad Brasilera Cardiología. 2010; 95 (2): 186-191.
Moreno G. Circunferencia de cintura: una medición importante y útil del riesgo cardiometabólico. Rev Chilena Cardiología. 2010; 29: 85-87.
Hernández T, Miguel S, Marrero H, Pérez L, Pena L, Rivas E. Comportamiento de variables clínicas, antropométricas y de Laboratorio en pacientes con síndrome metabólico. Medisur España. 2011; 9 (2): 22-28.
Friedewald W. Estimation of the concentration of Low density lipoprotein Cholesterol in plasma, Without Use of the Preparative Ultracentrifuge. The American Association of Clin. Chemistry. Inc. 1972.
Diabetes Federation International. The IDF Consensus Worldwide Definition of the Metabolic Syndrome. Brussels, International Diabetes Federation; 2006 [web site]. Available in: www.idf.org
Wikipedia, la enciclopedia libre [portal web]. Índice de masa corporal. Tabla de IMC. En: OMS para la Clasificación Internacional del estado nutricional en: infrapeso, sobrepeso y obesidad.