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2014, Number 1

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Rev Hosp Jua Mex 2014; 81 (1)

Resistencia a la insulina, síndrome metabólico, diabetes mellitus y carcinogénesis mamaria

Vargas-Hernández VM, Vargas-Aguilar VM, Moreno-Eutimio MA, Acosta-Altamirano G, Flores-Barrios K, Tovar-Rodríguez JM

Language: Spanish
References: 53
Page: 37-49
PDF size: 273.11 Kb.


ABSTRACT

Breast cancer (BC) is a heterogeneous disease, progressive, currently, are classified according to in pattern of gene expression luminal A, luminal B, basal and HER-2neu + and Triple-negative, 75 to 80% have receptors positive hormonal and 15 to 20% are positive for hER-2neu and 10 to 20% are triple negative, with hormone receptor negative and HER2-neu and their diagnostic is made by exclusion, the metabolic syndrome is related to a higher incidence of these cancers where the insulin-leptin axis-adiponectin are implicated in carcinogenesis.


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