2014, Number 5
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Cir Cir 2014; 82 (5)
Tissue regeneration strategies: cells, biochemical inductors, bionanomaterials and bioconstructions. Clinical and surgical achievements
Valdespino-Gómez VM, Valdespino-Castillo PM, Valdespino-Castillo VE
Language: Spanish
References: 43
Page: 578-589
PDF size: 421.91 Kb.
ABSTRACT
Regenerative medicine is a medical multidisciplinary area with the
aim of morphologic and functional restoration of tissues or organs in
order to re-establish normal function. The main bases of regenerative
medicine are the use of autologous stem or progenitor cells and the
ex
vivo construction of physical-mechanical tissue structuring organization,
which with stem cells may form bioartificial organs. Another eventual
strategy is
in vivo stem or progenitor cell stimulation for proliferation.
Tissue engineering entirely combines the use of cells, biochemical and
physicochemical factors, nanomaterials and bioengineering methods to
improve or replace biological functions of tissues and organs.
The progressive understanding of the proliferation and differentiation of
the process of stem cells and their
in vitro manipulation has been the
launching platform for the field of regenerative medicine.
In this review we describe the main strategies used for regenerative
medicine in tissue regeneration along with the main obtained clinicalsurgical
benefits.
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