2014, Number 5
<< Back Next >>
Rev Mex Neuroci 2014; 15 (5)
Findings on brain magnetic resonance image in twenty pediatric patients with Specific Language Impairment
Carmona-Vázquez CR, Peña-Landín DM, Cornelio-Nieto JO, Borbolla-Sala ME
Language: Spanish
References: 21
Page: 251-258
PDF size: 215.84 Kb.
ABSTRACT
Introduction: Children with specific language impairment (SLI) represent an heterogeneous group affecting different linguistic
dimensions, both in reception and in the expression. Stark and Tallal, proposed the current clinical criteria including: hearing level,
emotional and behavioral status, intellectual coefficient (IQ), neurological status, motor skills and speech reading level, all within
normal range, making the diagnosis by exclusion. The white matter has been associated with the speed processing and function
connectivity, and abnormalities associated with signal hyperintensities in children with delayed language development has been
estimated at 17-26% of cases.
Objetive: To describe brain MRI findings and to identify the risk factors in children with specific language impairment in the period
from July 2011 to July 2012.
Methods: Observational, prospective, cross-sectional analytical study including patients seen at the neurology clinic of the
Hospital “Dr. Rodolfo Nieto Padrón”. Brain magnetic resonance imaging was performed in twenty patients; we did a descriptive
analysis of the demographic data and findings in the brain MRI.
Results: A total of 50 patients were included; a 4:1 ratio in males was reported. Attention deficit hyperactivity disorder was
associated with TEL. We used the Rapin and Allen classification in which the most frequent type was type IV, 20 brain MRIs of 50
patients were performed with TEL, reporting 16 resonances with white matter hyper intensities and 4 normal magnetic resonances,
with 80% reporting white matter hyperintensities in different regions primary the periventricular zone.
Conclusions: The most common findings in brain MRI were hyperintensity of white matter in periventricular region following at the
occipital lobes, parietal lobes and semi-oval centers. Factors associated with specific language impairment such as family
history, chronic degenerative diseases, history of drug delivery and consumption were not associated with this pathology. We
observed that Attention deficit hyperactivity disorder was significantly associated with specific language impairment.
REFERENCES
Hammill D, Brown BS, Larsen SC, Wiederholt J. Test of Adolescent Language. Austin 2005; 278-304.
Holm V, Kunze L. Effect of chronic otitis media on language and speech develompent. Pediatrics 2007; 43: 833-9.
Bishop D, Leonard L. Speech and language impairments in children: causes, characteristics, intervention and outcome. Psychology Press 2001; 215-26.
Rapin I, Allen D. Developmental language disorders: nosologic considerations. In: Kirk U (ed.). Neuropsychology of Language. Reading and Spelling. Academic Press; 1983, p. 155-84.
Stark RE, Tallal P. Selection of children with specific language deficits. J Speech Hear Disord 2010; 46: 114-22.
Stark R, Tallal P. Language, speech, and reading disorders in children: neuropsychological studies. Little Brown; 2009, p. 180-220.
Leonard L. Children with specific language impairment. 4th. Ed. Mit Press PBK; 2000, p. 328-45.
Chevrie-Muller C. Trastornos específicos del desarrollo del lenguaje. En: Narbona J, Chevrie-Muller C (eds.). El lenguaje del niño. Desarrollo normal, evaluación y trastornos. Masson; 2001, p. 249-70.
Hurst JA, Baraitser M, Auger E, Graham F, Norell S. An extended family with a dominantly inherited speech disorder. Dev Med Child Neurol 2008; 32: 352-5.
Jernigan T, Hesselink JR, Sowell E, Tallal P. Cerebral structure on magnetic resonance imaging in language and learning impaired children. Arch Neurol 2002; 48: 539-45.
Verbruggen KT, Meiners LC, Sijens PE, Lunsing RJ, Van Spronsen FJ, Brouwer OF. Magnetic resonance imaging and proton magnetic resonance spectroscopy of the brain in the diagnostic evaluation of developmental delay. Eur J Paediatr Neurol 2009; 13: 181-90.
Badcock N. Co-localization of abnormal brain structure and function in specific language impairment. Brain & Language 2012; 120: 310-20.
Widjaja E, Nilsson D, Blaser S, Raybaud C. White matter abnormalities in children with idiopathic developmental delay. Acta Radiol 2009; 49: 589-95.
Kang C, Drayna D. Genetics of speech and language disorders. Annu Rev Genomics Hum 2011; 12: 145-64.
Wiszniewski W, Hunter JV, Hanchard NA, Willer JR, Shaw C, Tian Q. TM4SF20 Ancestral Deletion and Susceptibility to a Pediatric Disorder of Early Language Delay and Cerebral White Matter Hyperintensities. Am J Hum Genet 2013; 93: 197-210.
Prathanee B, Purdy SC, Thinkhamrop B, Chaimay B, Ruangdaraganon N, Mo-suwan L, Phuphaibul R. Early language delay and predictive factors in children aged 2 years. J Med Assoc 2009; 92: 930-8.
Redmond SM. Conversational profiles of children with ADHD, SLI and typical development. Clin Linguist Phon 2004; 18: 107-25.
Tirapu J, Luna P, Hernáez P, García I. Relación entre la sustancia blanca y las funciones cognitivas. Rev Neurol 2011; 12: 725-42.
Filley CM. Aspectos neuroconductuales de los trastornos de la sustancia blanca. Clínicas Psiquiátricas de Norteamérica 2005; 28: 685-700.
Guibert C, Maumet C, Jannin P, Ferre Jì, Treguier C, Barillot C, Le Rumeur E, et al. Abnormal functional lateralization and activity of language brain areas in typical specific language impairment (developmental dysphasia). Brain 2011; 134: 304-5.
Schlaug G, Marchina S, Norton A. Evidence for plasticity in white-matter tracts of patients with chronic Broca’s aphasia undergoing intense intonation-based speech therapy. Ann N Y Acad Sci 2009; 1169: