2014, Number 4
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Rev Med MD 2014; 5.6 (4)
Morphea in pediatrics a report of seven cases
Ávalos-Huizar XA, Valencia-Moran CD, Rodarte-Pérez JI, Castro-Mosqueda MG, Ornelas-Arana ML, Pérez-García G, Castillo-Villaruel F
Language: Spanish
References: 15
Page: 262-267
PDF size: 1135.83 Kb.
ABSTRACT
Morphea is a rare heterogeneous clinical disease characterized by the increase on the collagen deposition, in
consequence, skin sclerosis and subcutaneous tissues. This is the report of 7 cases that attended the skin pediatrics in the
Civil Hospital of Guadalajara during the period of January to April 2014. Case 1 with presence of mixed morphea
(Parry-Romberg syndrome with en coup de sabre). Case 2 with plaque-type morphea. Case 3 and 4 with en coup de
sabre. Case 5 plaque-type morphea. Case 6 mixed (plaque-type and en coup de sabre). Case 7 hemicorporalmorphea.
We do a brief literature review. Despite of being a rare disease it is of interest the raise on their presentation, as well as
an earlier age onset.
REFERENCES
Fett N, Werth VP. Update on morphea. Part I. Epidemiology, clinical presentation and pathogenesis. J Am Acad Dermatol 2011; 64: 217-28.
Pope E, Laxer RM. Diagnosis and management of morphea and lichen sclerosus and atrophicus in children. Pediatr Clin North Am. 2014; 61(2): 309-19.
Laxer RM, Zulian F. Localized scleroderma. Curr Opin Rheumatol 2006; 18: 606-13.
Handler MZ, Wulkan AJ, Stricker SJ, Schachner LA. Linear morphea and leg lenght discrepancy: treatment with a leg-lengthening procedure. Pediatr Dermatol 2013; 30(5): 616-8.
Francés C, Barete S, Lipsker D. Morphées. EMC (Elsevier Masson SAS, París), Dermatologie, 98-505- B-10, 2010.
Hassan ML, Saposnik M, Melloni ME, Waiman J, Moreno-Figuerodo A, Spiner RE, Schroh RG. Morfeas hemicorporales: estudio de 7 casos. Rev Arg Reumatol. 2013; 24:1: 8-14.
Chiu YE, Vora S, Kwon EK, Maheshwari M. A significant proportion of children with morphea en coup de sabre and Parry-Romberg syndrome have neuroimaging findings. Pediatr Dermatol 2012; 29(6): 738-748.
Janowska M, Katarzyna P, Wojas-Pelc A, Lipko- Gdlewska A. Coexistence of Parry-Romberg syndrome with homolateral segmental vitiligo. Postepy Dermatol Alergol. 2013; 30(6): 409-11.
Bonifati C, Impara G, Morrone A, et al. Simultaneous occurrence of linear scleroderma and homolateral segmental vitiligo. J Eur Acad Dermatol Venereol. 2006; 20: 63-5. 10.Creus L, Sanchez-Regana M, Salleras M, et al. Syndrome de Parry-Romberg associé à un vitiligo segmentaire homolatéral. Ann Dermatol Venereol. 1994; 121: 710-1. 11.Khaled A, Kharfi M, Ramheh S, Zermani R, Fazaa B. Postvaccination morphea profunda in a child. Pediatr Dermatol 2012; 29(4): 525-7.
Startori-Valinotti JC, Tollefson MM, Reed AM. Updates on morphea: role of vascular injury and advances in treatment. Autoinmmune Dis. 2013.
Odhav A, Hoeltzel MF, Canty K. Pansclerotic morphea with features of eosinophilic fasciiitis: distinct entitites or part of a continuum? Pediatr Dermatol 2014; 31(2): e42-e47.
Kutasi Z, Weisensee P, Battyani Z, Ruizecka T. "Borrelia- associated early-onset morphea": a particular type of scleroderma in childhood an adolescence with high titer antinuclear antibodies? J Am Acad Dermatol 2009; 60: 248-55.
Taniguchi T1, Asano Y, Tamaki Z, Akamata K, Aozasa N, Noda S, Takahashi T, Ichimura Y, Toyama T, Sugita M, Sumida H, Kuwano Y, Miyazaki M, Yanaba K, Sato S. Histological features of localized scleroderma 'en coup de sabre': a study of 16 cases. J Eur Acad Dermatol Venereol. 2013.
Fett N., Werth VP. Update on morphea II. J Am Acad Dermatol 2011; 64: 231-42.
Kroft EB, Groeneveld TJ, Seyger MM, de Jong EM. Efficacy of topical tacrolimus 0.1% in active plaque morphea: randomized,double-blind, emollientcontrolled pilot study. Am J ClinDermatol 2009; 10: 181-7.