2014, Number 610
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Rev Med Cos Cen 2014; 71 (610)
Actualización sobre el uso de Hipoglicemiantes orales para el tratamiento farmacológico en diabetes mellitus gestacional
García-Herrera E
Language: Spanish
References: 27
Page: 225-229
PDF size: 208.05 Kb.
ABSTRACT
Clinical guidelines regarding
gestational diabetes aim only to
the use of insulin as traditional
therapy; oral hypolycemic
agents such as metformin or
glyburide are not yet approved
by official guidelines, however,
many authors consider the use of
oral hypoglicemic agents as first
line treatment for patients who
fail to maintain hipoglicemia
with diet and exercise only.
There is no consistent evidence
of risk for developing adverse
reactions both to the fetus or
to the mother with the use of
these medications compared
to the use of insulin, even so,
there is an arising number of reports, observational studies,
randomized and comparative
trials, which might lead in
the future to new guidelines
of treatment, yet there is still
controversy regarding the use
of these agents as treatment
option for gestational diabetes.
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