2014, Number 4
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Rev Fac Med UNAM 2014; 57 (4)
Fever
Ramón-Romero F, Farías JM
Language: Spanish
References: 57
Page: 20-33
PDF size: 449.29 Kb.
ABSTRACT
One of the most common signs of numerous human diseases,
especially infectious ones, is fever, characterized by
a temperature generally taken on the skin and higher than
37
° C. Historically, fever has been considered a sign of the
disease itself. However, recent studies suggested by Evolutive
Medicine view, indicate that fever is also a mechanism
through which the organism fights external invaders. Here
we review the modern concepts about fever as a basis to
suggest clinicians to pay attention to fever, avoiding the use
of antipyretics to eliminate it, without assessing its possible
benefitial effects.
REFERENCES
Boulant, JA. Role of the preoptic-anterior hypothalamus in thermoregulation and fever. Clin Infect Dis. 2000;31(Suppl. 5):S157-S161.
Whitrow M. Wagner-Jauregg and fever therapy. Med Hist. 1990;34:294-310.
Plaisance KI, Kudaravalli S, Wasserman SS, Levine MM, Mackowiak PA. Effect of antipyretic therapy on the duration of illness in experimental influenza A, Shigella sonnei, and Rickettsia rickettsii infections. Pharmacotherapy. 2000;20(12):1417-22.
Doran TF, De Angelis C, Baumgardner RA, Mellits ED. Acetaminophen: more harm than good for chickenpox? J Pediat. 1989;114:1045-8.
Schulman CI, Namias N, Doherty J, et al. Effect of antipyretic therapy upon outcomes in critically ill patients: a randomized, prospective study. Surg Infect. 2005;6:369-75.
El-Radhi AS. Why is the evidence not affecting the practice of fever management? Arch Dis Child. 2008;93:918-20.
Busch W. Einfluβ von Erysipel. Berliner Klin. Wschr. 1866; 3:245-6.
Fehleisen V. VI. Über die Züchtung der Erysipel kokken auf künstlichem Nährboden und Ihre Übertragbarkeit auf den Menschen. Dtsch Med. Wochenschr. 1882;18:533-54.
Richter PF. Leukemia and Erysipel. Charite-annalens. 1896; 21:299-309.
Laurence JZ. The diagnosis of surgical cancer (Lister Prize for 1854). London: Churchill; 1854.
Coley WB. Treatment of inoperable malignant tumors with toxins of erysipelas and the bacillus prodigious. Trans Am Surg Assoc. 1894a;12:183-212.
Coley WB. Further observations upon the treatment of malignant tumors with the Toxins of erysipelas and Bacillus prodigious with a report of 160 cases. Bull. John Hopkins Hospital. 1896a;7:175
Coley WB. The therapeutic value of the mixed toxins of the streptococcus of erysipelas and bacillus prodigious in the teratment of inoperable malignant tumors. With a report of 160 cases. Am J Med Sci. 1896b;112:251-81.
Coley WB. Endothelioma myeloma of tibia: Long-standing cure by Toxin treatment. Ann Surg. 1931;94:447-52.
Coley WB, Coley BL. Primary malignant tumors of the long bones. Archiv Surg. 1926;13780-836/14.836/14 63- 141.
Issels J. Immunotherapy in progressive metastatic cancer. Clin Trials J. 1970;3: 357-66.
Hager ED, Abel U, editores. Biomodulation und Biotherapie des Krebses II. Endogene Fiebertherapie und exogene Hyperthermie in der Onkologie. Heidelberg: Verlag für Medizin Dr. E. Fischer. 1987.
Wiemann B, Starnes CO. Coley’s Toxins, Tumor necrosis factor and cancer research: A historical perspective. Pharmacol Ther. 1994;64(3):529-64.
Kleef R, Jonas WB, Knogler W, Stenzinger W. Fever, cancer incidence and spontaneous remissions. Neuroimmunomodulation. 2001;9(2):55-64.
Kanner L. Autistic disturbances of affective contact. Nervous Child. 1943;2:217-50.
Comi AM, AW Zimmerman, VH Frye, PA Law, and JN Peeden. Familial clustering of autoimmune disorders and evaluation of medical risk factors in autism. J. Child Neurol. 1999; 14(6): 388-394.
Urakubo A, Jarskog LF, Lieberman JA, Gilmore JH. Prenatal exposure to maternal infection alters cytokine expression in the placenta, amniotic fluid and fetal brain. Schizophrenia Res. 2001;47:27-36.
Giralt M, Penkowa M, Hernandez J, Molinero A, Carrasco J, Lago N, et al. Metallothionein-1+2 Deficiency Increases Brain Pathology in Transgenic Mice with Astrocyte-Targeted Expression of Interleukin 6. Neurobiology of Disease. 2002;9:319-38.
Ciaranello AI, Ciaranello RD. The neurobiology of infantile autism. Annu Rev Neurosci. 1995;18:101-28.
Hornig M, Weissenbock H, Horscroft N, Lipkin WI. An infection-based model of neurodevelopmental damage. Proc Natl Acad Science. 1999;96(21):12102-7.
Patterson PH. Maternal infection: window on neuroimmune interactions in fetal brain development and mental illness. Curr Opin Neurobiol. 2002;12:115-8.
Pletnikov MV, Moran TH, Carbone KM. Borna Disease Virus Infection of the Neonatal Rat: Developmental Brain Injury model of Autism Spectrum Disorders. Frontiers in Bioscience. 2002;7,1:d593-607.
Kemper TL, Bauman M. Neuropathology of infantile autism. J Neuropathol Exp Neurol. 1998;57:645-52.
Sweeten TL, Posey DJ, Shekhar A, McDougle CJ. The amygdala and related structures in the pathophysiology of autism. Pharmacol Biochem Behavior. 2002;71:449-55.
Nelson KB, Grether JK, Croen LA, Dambrosia JM, Dickens BF, Jelliffe LL, et al. Neuropeptides and neuro-trophins in neonatal blood of children with autism or mental retardation. Ann Neurol. 2001;49:597-606.
Roberts NJ Jr., Steigbigel RT. Hyperthermia and human leukocyte functions: effects of response of lymphocytes to mitogens and antigens and bacterial capacity of monocytes and neutrophils. Infect Immun. 1977;18:673-9.
Heron I, Berg K. The actions of interferon are potentiated at elevated temperature. Nature Lond. 1978;274:508-10.
Yerushalmi A, Tovey M, Gresser I. Antitumor effect of combined interferon and hyperthermia in mice. Proc Soc Exp Biol Med. 1982;169:413-5.
Haahr S, Mogensen S. Function of fever. Lancet. 1977;2:613.
Vaughn LK, Veale WL, Cooper KE. Antipyresis effect on mortality rate of bacterially infected rabbits. Brain Res Bull. 1980;5:69-73.
Husseini RH, Sweet C, Collie MH, Smith H. Elevation of nasal viral levels by suppression of fever in ferrets infected with influenza viruses of differing virulence. J Infect Dis. 1982;145:520-4.
Goetzl L, Evans T, Rivers J, Suresh MS, Lieberman E. Elevated maternal and fetal serum interleukin-6 levels are associated with epidural fever. Am J Obstet Gynecol. 2002;187(4):834-8.
De Jongh RF, M Puylaert, E Bosman, W Ombelet, M Maes, R Heylen. J Perinatol. 1999;16(3):121-8.
Marz P, Heese K, Dimitriades-Schmutz B, Rose-John S, Otten U. Role of Interleukin 6 and Soluble IL-6 Receptor in Region-Specific Induction of Astrocytic Differentiation and Neuro-trophin Expression. Glia. 1999;26:191-200.
Torres AR. Is fever suppression involved in the etiology of autism and neurodevelomental disorders. BMC Pediatrics. 2003;3:9.
Rimland B. The autism increase: research needed on the vaccine connection. Autism Res Rev Int. 2000;14:3-6.
Schultz ST, Klonoff-Cohen HS, Wingard DL, et al. Acetamnophen (paracetamol) use, measless-mumps-rubella vaccination, and autistic disorder: the results of a parent survey. Autism. 2008;12:293-307.
Good P. 2009. Did acetaminophen provoke the autism epidemic? Alt Med Rev. 14(4):364-72
Luheshi GN. Cytokines and fever. Mechanisms and sites of action. Ann NY Acad Sci. 1998;856:83-9.
LeGrand EK, Alcock J. Turning up the heat: inmune brinksmanship in the acute-phase response. Q Rev Biol. 2012;87:3-18.
Aronoff DM, Neilson EG. Antipyretics: Mechanisms of action and clinical use in fever suppression. Am J Med. 2001;111(4):304-15.
Saper CB, Breder CD. The neurologic basis of fever. N Engl J Med. 1994;330(26):1880-6.
Kluger MJ, Kozak W, Conn C, Leon L, Soszynski D. The adaptive value of fever. Infect Dis Clin North Am. 1996;10(1):1-20.
Kluger MJ. Fever in Ectotherms: Evolutionary implications. Amer Zool. 1979a;19(1):295-304.
Kluger MJ, Ringler DH, Anver MR. Fever and survival. Science. 1975;188(4184):166-8.
Kluger MJ, Rothenburg BA. Fever and reduced iron: Their interaction as a host defense response to bacterial infection. Science. 1979b;203(4378):374-6.
Kozak W. Fever: A possible strategy for membrane homeostasis during infection. Perspect Biol Med. 1993;37(1):14-34.
Elin R, Wolff S, Finch C. Effect of induced fever on serum iron and ferritin concentrations in man. Blood. 1997;49:147-53.
Chandrasekharan NV, Dai H, Turepu Roos KL, et al. COX- 3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Proc Natl Acad Sci USA. 2002:99(21);13926-31.
Maclagan TJ. The treatment of acute rheumatism by salicin. Lancet. 1876;i:342-83.
Dresser H. Pharmacologisches über Aspirin (Acetylsalicylsaüre). Pflugers Arch. 1899;76:306-18.
Vane JR, Botting RM. The mechanism of action of aspirin. Thrombosis Res. 2003;110:235-58.