2012, Number 2
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RCAN 2012; 22 (2)
El intestino delgado, las incretinas y el metabolismo glucídico en la Diabetes mellitus
Ochoa C
Language: Spanish
References: 45
Page: 301-313
PDF size: 123.90 Kb.
ABSTRACT
Research completed in recent years has revealed
the important role small bowel plays in the
body’s energy homeostasis through incretins:
enterohormones that regulate the equilibrium
between the influences of insulin and glucagon
upon glucose metabolism, stomach emptying,
and growth and development of β cells present
in the pancreatic islets. Biological actions of
incretins have been recognized in subjects in
whom remission of insulin resistance has been
observed following bariatric surgery. Intimate
knowledge of the biology and effect of incretins
have been translated into new therapeutic and
pharmaceutical approaches in the treatment of
Diabetes mellitus.
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