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2005, Number 4

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Med Sur 2005; 12 (4)

Procalcitonin, as an useful marker for severe infections

Remolina-Schlig M

Language: Spanish
References: 21
Page: 189-190
PDF size: 42.70 Kb.


ABSTRACT

Procalcitonin (PC) is a useful marker for severe infections. In many systemic inflammatory conditions, the levels of PC increase in serum according to the response of the body. In severe trauma, acute pancreatitis or localized infections, PC increases to lesser levels to those seen in severe bacterial, fungal or protozoan infections. By contrast in severe viral infections PC remains at very low levels supporting the differential diagnosis. During antibiotic treatment PC levels help decide to stop or modify treatment according to changes in serum levels. In contrast to reactive protein C whose levels increase in nonspecific manner, PC levels reflect tightly the body response to severe infections. In other cases with severe inflammatory reaction and no infection, PC levels allow to differentiate between acute pancreatitis with severe inflammatory reaction from that with infected pancreatic necrosis.


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