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2014, Number 1

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Rev Cubana Plant Med 2014; 19 (1)

Medicinal use of antidiabetic plants in Oaxacan ethnobotanical tradition

Castro JCJ, Villa RN, Ramírez GSA, Mosso GC

Language: Spanish
References: 59
Page: 101-120
PDF size: 183.80 Kb.


ABSTRACT

Introduction: type 2 diabetes mellitus (DM2) is one of the most common chronic degenerative diseases in Mexico. Medicinal plants are one of the treatments provided to the Oaxacan population suffering from this disease.
Objective: carry out an exhaustive bibliographic review in electronic scientific databases with the purpose of collecting information about antidiabetic plants and hypoglycemic extracts empirically used in Oaxaca, Mexico.
Methods: an exhaustive bibliographic search was conducted for scientific studies dealing with the biological activity (in vitro and in vivo tests) and chemical characteristics of plants commonly used to treat diabetes in the state of Oaxaca, Mexico.
Results: a presentation is made of 35 plants from 22 botanical families which are used to treat type 2 diabetes mellitus. Most of these species are from the families Lamiaceae, Cecropiaceae and Equisetaceae. In 23 of the 35 species, antidiabetic action was tested in animal models, and only in 19 of them could compounds with hypoglycemic activity be identified.
Conclusion: about 77 % of these plants have reports on the effect of their extracts or their individual secondary metabolites. Some of the plants used empirically in the state of Oaxaca, Mexico, contain clearly identified flavonoids and terpenes with antioxidant activity and inhibitory action on enzymes involved in carbohydrate metabolism. Previous in vitro and in vivo assays have shown that certain members of these metabolite families have an obvious effect on glycemia regulation. These findings consistently support the millenarian use of the species herein dealt with.


REFERENCES

  1. Andrade-Cetto A, Wiedenfeld H. Anti-hyperglycemic effect of Opuntia streptacantha Lem. J Ethnopharmacol. 2011;133(2):940-3.

  2. Becerra-Jiménez J, Andrade-Cetto A. Effect of Opuntia streptacantha Lem on alpha-glucosidase activity. J Ethnopharmacol. 2012;139(2):493-6.

  3. Verner CR. Oral Hypoglycemic Agents: The usual way to proceed and special situations. Rev Med Clin Las Condes. 2009;20(5):595-602.

  4. Hernández-Galicia E, Aguilar-Contreras A, Aguilar-Santamaría L, Román-Ramos R, Chávez-Miranda AA, García-Vega LM, et al. Studies on hypoglycemic activity of Mexican medicinal plants. Proc West Pharmacol Soc. 2002;45(1):118-24.

  5. Andrade-Cetto A, Heinrich M. Mexican plants with hypoglycaemic effect used in the treatment of diabetes. J Ethnopharmacol. 2005;99(3):325-48.

  6. Xiaorui Z. Regulatory situation of herbal medicines - A world wide review. Geneva: World health organization; 1998. p. 11.

  7. Merina A, Sivanesan D, Hazeena BV, Sulochana V. Antioxidant and hypolipidemic effect of Plumeria rubra L. in alloxan induced hyperglycemic rats. E-J Chem. 2010;7(1):1-5.

  8. Abad-Reyes A, Bahsas A, Delgado-Méndez P, Amaro-Luis JM, Neil TGH. Actividad antimicrobiana y estudio fitoquímico preliminar de Mandevilla veraguasensis (Seem.) Helms. (Apocynaceae). Avances Química. 2006;1(3):29-34.

  9. Patel V, Chitra V, Prasanna P, Krishnaraju V. Hypoglycemic effect of aqueous extract of Parthenium hysterophorus L. in normal and alloxan induced diabetic rats. Indian J Pharmacol. 2008;40(4):183-5.

  10. Alonso-Castro AJ, Zapata-Bustos R, Romo-Yañez J, Camarillo-Ledesma P, Gómez-Sánchez M, Salazar-Olivo LA. The antidiabetic plants Tecoma stans (L.) Juss. ex Kunth (Bignoniaceae) and Teucrium cubense Jacq (Lamiaceae) induce the incorporation of glucose in insulin-sensitive and insulin-resistant murine and human adipocytes. J Ethnopharmacol. 2010;127(1):1-6.

  11. Glasby J. Dictionary of plants containing secondary metabolites. London: Taylor and Francis; 1991. p. 57, 264, 314.

  12. Lozoya-Meckes M, Mellado-Campos V. Is the Tecoma stans infusion an antidiabetic remedy? J Ethnopharmacol. 1985;14(1):1-9.

  13. Kazmi I, Afzal M, Anwar F. Characterization and anti-diabetic evaluation of Lantana camara. Ursolic acid derivative with potent pharmacological significance. Germany: LAP Lambert Academic Publishing; 2012. p. 144.

  14. Aguilar-Santamaría L, Ramírez G, Nicasio P, Alegría-Reyes C, Herrera-Arellano A. Antidiabetic activities of Tecoma stans (L.) Juss. ex Kunth. J Ethnopharmacol. 2009;124(2):284-8.

  15. Al-Azzawi AM. Genotoxic and cytotoxic study of Tecoma stans Bignoniaceae. Pakistan J Biol Sci. 2011;15(2):92-7.

  16. Pérez-Gutiérrez RM, Mota FJM. Attenuation of hyperglycemia and hyperlipidemia in streptozotocin-induced diabetic rats by chloroform extract of fruits of Ferocactus latispinus and Ferocactus histrix. Bol Latinoam Caribe Plant Med Aromat. 2010;9(6):475-84.

  17. Ramírez G, Zavala M, Pérez J, Zamilpa A. In vitro screening of medicinal plants used in Mexico as antidiabetics with glucosidase and lipase inhibitory activities. Evid Based Complement Alternat Med. 2012(1):0-6.

  18. Andrade-Cetto A, Wiedenfel H. Hypoglycemic effect of Acosmium panamense bark on streptozotocin diabetic rats. J Ethnopharmacol. 2004;90(2-3):217-20.

  19. Andrade-Cetto A, Wiedenfeld H, Revilla-Monsalve MC, Islas AS. Hypoglycemic effect of Equisetum myriochaetum aerial parts on streptozotocin diabetic rats. J Ethnopharmacol. 2000;72(1-2):129-33.

  20. Revilla-Monsalve MC, Andrade-Cetto A, Islas-Andrade S, Wiedenfeld H. Hypoglycemic effect of Equisetum myriochaetum aerial parts on type 2 diabetic patients. J Ethnopharmacol. 2002;81(1):117-20.

  21. Bárcenas-Rodríguez H. Determinación del efecto genotóxico de Equisetum myriochaetum en células somáticas de alas de Drosophila melanogaster [Tesis Licenciatura en Biología]. México: Facultad de Ciencias, UNAM; 2004.

  22. Loarca-Piña G, Mendoza S, Ramos-Gómez M, Reynoso R. Antioxidant, antimutagenic, and antidiabetic activities of edible leaves from Cnidoscolus chayamansa Mc. Vaugh. J Food Sci. 2010;75(2):68-72.

  23. Molina CA, Curley WL, Bressani R. Redescubriendo el valor nutritivo de las hojas de chaya (Cnidoscolus aconitifolius; Euphorbiaceae). Cienc Acción (Gua) [Internet]. 1997;(3). [aprox. 3 p] [citado 25 Ene 2013]. Disponible en: http://kirika.uvg.edu.gt/info-academica/u-academicas/inst-investold/ boletin/b3/cienac3.html

  24. Figueroa-Valverde L, Díaz-Cedillo F, Camacho-Luis A, López-Ramos M. Efeitos induzidos por Ruta graveolens L., Rutaceae, Cnidoscolus chayamansa McVaugh, Euphorbiaceae, e Citrus aurantium L., Rutaceae, nos níveis de glucose, colesterol e triacilglicerídeos num modelo do rato diabético. Braz J Pharmacogn. 2009;19(4):898-907.

  25. Mazumder PM, Rathinavelusamy P, Sasmal D. Role of antioxidants in phytomedicine with special reference to antidiabetic herbs. Asian Pac J Trop Dis. 2012;2(S2):969-79.

  26. Tachakittirungrod S, Chowwanapoonpohn S. Comparison of antioxidant and antimicrobial activities of essential oils from Hyptis suaveolens and Alpinia galanga growing in Northern Thailand. CMU J Nat Sci. 2007;6(1):31-41.

  27. Mishra SB, Verma A, Mukerjee A, Vijayakumar M. Anti-hyperglycemic activity of leaves extract of Hyptis suaveolens L. Poit in streptozotocin induced diabetic rats. Asian Pac J Trop Med. 2011;4(9):689-93.

  28. Kadri A, Zarai Z, Békir A, Gharsallah N, Damak M, Gdoura R. Chemical composition and antioxidant activity of Marrubium vulgare L. essential oil from Tunisia. Afr J Biotechnol. 2011;10(19):3908-14.

  29. Vergara-Galicia J, Aguirre-Crespo F, Tun-Suarez A, Aguirre-Crespo A, Estrada- Carrillo M, Jaimes-Huerta I, et al. Acute hypoglycemic effect of ethanolic extracts from Marrubium vulgare. Phytopharmacology. 2012;3(1):54-60.

  30. Nawwar MAM, El-Mousallamy AMD, Barakat HH, Buddrus J, Linscheid M. Flavonoid lactates from leaves of Marrubium vulgare. Phytochemistry. 1989;28(11):3201-6.

  31. Elberry AA, Harraz FM, Ghareib SA, Gabr SA, Nagy AA, Abdel-Sattar E. Methanolic extract of Marrubium vulgare ameliorates hyperglycemia and dyslipidemia in streptozotocin-induced diabetic rats. Int J Diab Mellit [Internet] 2011 Feb. [aprox. 1 p] [citado 25 Ene 2013]. Disponible en: http://dx.doi.org/10.1016/j.ijdm.2011.01.004

  32. Ibrahim TA. Chemical composition and biological activity of extracts from Salvia bicolor Desf. growing in Egypt. Molecules. 2012;17:11315-34.

  33. Saeidnia S, Ghamarinia M, Gohari AR, Shakeri A. Terpenes from the root of Salvia hypoleuca Benth. DARU J Pharma Sci. 2012;20(1):0-6.

  34. Mahesh KP, Sasmal D, Mitra MP. The antihyperglycemic effect of aerial parts of Salvia splendens (scarlet sage) in streptozotocin-induced diabetic-rats. Pharm Res. 2010;2(3):190-4.

  35. Kamel MEA. Antidiabetic, antihypercholestermic and antioxidative effect of Aloe vera gel extract in alloxan induced diabetic rats. Aust J Basic Appl Sci. 2011;5(11):1321-7.

  36. Vargas F, Díaz Y. Estudios in vitro de los mecanismos fotooxidantes y antioxidantes de los principios activos de la Aloe vera. Rev Fac Farm. 2003;45(1):65-8.

  37. Argueta VA. Atlas de las Plantas de la Medicina Tradicional Mexicana. México: Instituto Nacional Indigenista; 1994. p. 3.

  38. Andrade Cetto A. Mexican plants traditionally used for the treatment of type 2 diabetes. En: Hiriart-Urdanivia M, Mas-Oliva J, editores. Advances in obesitydiabetes research at UNAM. México: Manual Moderno; 2010. p.191-200.

  39. Hemmerle H, Burger HJ, Below P, Schubert G, Rippel R, Schindler PW, et al. Chlorogenic acid and synthetic chlorogenic acid derivatives: Novel inhibitors of hepatic glucose-6-phosphate translocase. J Med Chem. 1997;40(2):137-43.

  40. Nicasio P, Aguilar-Santamaría L, Aranda E, Ortiz S, González M. Hypoglycemic effect and chlorogenic acid content in two Cecropia species. Phytother Res. 2005;19(8):661-4.

  41. Zafar-Imam M, Akter S. Musa paradisiaca L. and Musa sapientum L.: A phytochemical and pharmacological review. J Appl Pharm Sci. 2011;01(05):14-20.

  42. Román-Ramos R, Flores-Sáenz JL, Partida-Hernández G, Lara-Lemus A, Alarcón-Aguilar F. Experimental study of the hypoglycemic effect of some antidiabetic plants. Arch Invest Med (Mex). 1991;22(1):87-93.

  43. Pérez-Gutiérrez RM. Actividad hipoglucemiante de Salpianthus arenarius, Acrocomia mexicana, Agarista mexicana y Verbesina persicifolia [Tesis Doctorado en Ciencias Biológicas]. México: Universidad Autónoma Metropolitana, Unidad Iztapalapa; 1997.

  44. Marroquín SR, Flores M, García M, Mora JL. Efecto antihiperglucémico de un extracto acuoso de Columbrina elíptica. Rev Mex Cienc Farm. 2005;36(6):27-32.

  45. Cruz-Gallegos J. Relación flavonoides totales-actividad antidiabética (in vitro por difusión de glucosa) en extractos de Colubrina elliptica [Tesis Ingeniero en Alimentos]. Huajuapan de León, Oaxaca, México: Universidad Tecnológica de la Mixteca; 2012.

  46. Sánchez J, Martínez G, García F. Efecto protector de los polifenoles de Rhizophora mangle L. sobre el daño oxidativo a proteínas y ADN. Rev Cubana Plant Med. 2011;16(1):1-12.

  47. Alarcón-Aguilara FJ, Román-Ramos R, Pérez-Gutiérrez S, Aguilar-Contreras A, Contreras-Weber CC, Flores-Saenz JL. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol. 1998;61:101-10.

  48. Sánchez J, Melchor G, Martínez G, Escobar A, Faure R. Antioxidant activity of Rhizophora mangle bark. Fitoterapia. 2006;77(2):141-3.

  49. Chen J, Li WL, Wu JL, Ren BR, Zhang HQ. Hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (Eriobotrya japonica (Thunb.) Lindl.). Phytomedicine. 2007;15(1-2):98-102.

  50. Lü H, Chen J, Li JL, Ren BR, Wu JL, Kang HY, et al. Hypoglycemic and hypolipidemic effects of the total triterpene acid fraction from Folium eriobotryae. J Ethnopharmacol. 2009;122(3):486-91.

  51. Venkatachalam T, Kishor KV, Kalai SP, Maske A, Anbarasan V, Siva KP. Antidiabetic activity of Lantana camara Linn fruits in normal and streptozotocin induced diabetic rats. J Pharm Res. 2011;4(5):1550-2.

  52. Padilla Gómez E. Estudio ecológico y etnobotánico de la vegetación del municipio de San Pablo Etla, Oaxaca [Tesis Maestro en Ciencias de Conservación y Aprovechamiento de Recursos]. México: Instituto Politécnico Nacional; 2007.

  53. Aguilar A, López-Villafranco ME, Xolalpa-Molina S. Los tratamientos populares y el personal de salud. Relevancia de la herbolaria. Servicios de Salud con Calidad Intercultural en Pueblos Amerindios. 2003 [citado 13 enero 2013]: 1-93. [aprox. 5 p]. Disponible en: http://bvs.per.paho.org/texcom/cd048358/tratamie.pdf

  54. Cervantes-Servín L, Valdez Gutiérrez J. Plantas medicinales del distrito de Ocotlán Oaxaca. Anales Inst Biol UNAM Ser Bot. 1990;60(1):85-103.

  55. Pérez-García V. Plantas medicinales de uso en traspatio de la zona centro del estado de Veracruz [Tesis licenciado en biología]. Veracruz, México: Universidad Veracruzana; 2009.

  56. Biblioteca digital de la medicina tradicional mexicana. [Internet] UNAM [citado 25 Ene 2013]. [aprox. 3 p]. Disponible en: http://www.medicinatradicionalmexicana.unam.mx

  57. CONABIO. [Internet]. Herbario virtual [citado Ene 25 2013]. [aprox. 5 p]. Disponible en: http://www.conabio.gob.mx/otros/cgi-bin/herbario.cgi

  58. Gallardo-Pérez JC, Esparza-Aguilar Ml, Gómez-Campos A. Importancia etnobotánica de una planta vascular sin semilla en México: Equisetum. Polibotanica. 2006;21:61-74.

  59. Bautista-Cruz A, Arnaud-Viñas MR, Martínez-Gutiérrez GA, Sánchez-Medina PS, Pérez Pacheco R. The traditional medicinal and food uses of four plants in Oaxaca, Mexico. J Med Plants Res. 2011; 5(15):3404-11.




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