medigraphic.com
ISSN 2225-4676 (Electronic)

2012, Number 1

<< Back Next >>

Rev Cubana Neurol Neurocir 2012; 2 (1)

Anatomo–pathological and demographic considerations of intracranial metastases

Caballero GJ, Felipe MA, Toledo VC, Pérez OP, Morales PI

Language: Spanish
References: 18
Page: 23-27
PDF size: 108.71 Kb.


ABSTRACT

Objective: To determine the anatomo–pathological and demographic characteristic of the brain metastases of a group of deceased’s in the Hospital “Dr. Carlos J. Finlay” during the period: January of 1976 – December of the 2006.
Methods: It was carried out a traverse retrospective descriptive observational study of 1177 autopsies with metastatic tumor. It was used as source the Registrations of Autopsies.
Results: Of the 1177 deceased’s with metastasis, 204 (17.3 %) presented intracranial metastasis; 65.2% of masculine sex and 34,8 % feminine. The lung constituted the most frequent localization in the primary tumors, and carcinoma epidermoide was the prevailing histological variant. The intracranial solitary metastasis had the biggest incidence in the sample, being the parietal localization of these the most numerous.
Conclusions: In patients with metastasis, the intracranial lesions occupy a high frequency. In our study was interesting the low metastatic incidence that presented the skin and the lung to the brain.


REFERENCES

  1. Platta CS, Khuntia D, Mehta MP, Suh JH. Current treatment strategies for brain metastasis and complications from therapeutic techniques: a review of current literature. Am J Clin Oncol. 2010;33:398–407.

  2. Kocher M, Soffietti R, Abacioglu U, Villa S, Fauchon F, Baumert BG, et al. Adjuvant whole–brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952–26001 study. J Clin Oncol. 2011;29:134–41.

  3. Lacerda Gallardo AJ, Estenoz Esquivel JC, Borroto Pacheco R. Metástasis cerebral: Estudio clinicoquirúrgico y anatomopatológico. Rev Cubana Cir. 2000;39:103–7.

  4. Kim PE, Zee CS. Imaging of the cerebrum. Neurosurgery. 2007;61[SHC Suppl 1]:SHC–123–SHC–146.

  5. Ruiz Rebollo ML, Jiménez Carmena JJ, Madrigal Rubiales B, Escudero Caro T. Brain metastasis caused by colorectal carcinoma. Rev Esp Enferm Dig. 2009;101:221–2.

  6. Poblete PT, Donoso CMT, Holzer MF. Caracterización de pacientes operados de metástasis cerebral en el Instituto de Neurocirugía Asenjo (INCA). Rev Chil Neuro–Psiquiatr. 2008;46(2):101–6.

  7. Steeg PS, Camphausen KA, Smith QR. Brain Metastases as preventive and therapeutic targets. Nat Rev Cancer. 2011;11(5):352–63.

  8. Braakhuis BJM, Senft A, de Bree R, de Vries J, Ylstra B, Cloos J, et. Al. Expression profiling and prediction of distant metastases in head and neck squamous cell carcinoma. J Clin Pathol. 2006;59:1254–60.

  9. Lovo IE, Torrealba GM, Villanueva GP, Germen R, Tagle MP. Metástasis Cerebral y sobrevida. Rev Med Chile. 2005;133(2):190–4.

  10. Moore KL. Fundamentos de anatomía clínica. 2ª.ed. Rio de Janeiro. Guanabara–Koogan; 2004. p. 301–5.

  11. Cordeiro JG, Prevedello DMS, Ditzel LFdS, Pereira CU, Araújo JC. Cerebral metastasis of cervical uterine cancer: report of three cases. Arq Neuro–Psiquiatr. 2006;64:300– 2.

  12. Sharon K. Inouye MD. Delirium in older persons. N Engl J Med. 2006;354:1157–65.

  13. Polavieja CM, Lago VJ, Ramos RE, Gómez PA, López JM. Alternativas quirúrgicas de la enfermedad metastásica. Clin Transl Oncol. 2004;20(6):360 – 73.

  14. González EP, Massardo VT, Canessa GJ. Artículo de revisión Aplicaciones clínicas del PET. Rev Med Chile. 2002;130:569–79.

  15. Boya MJ, Alonso A. ¿Reciben un tratamiento adecuado los pacientes ancianos con cáncer? Rev Esp Ger y Ger. 2005;40(6):371–7.

  16. Tsao MN, Lloyd N, Wong R, Chow E, Rakovitch E, Laperriere N. Radioterapia total del cerebro para el tratamiento de las metástasis cerebrales múltiples (Revisión Cochrane traducida). En: La Biblioteca Cochrane Plus, número 3, 2008. Oxford, Update Software Ltd. Disponible en: http://www.update–software.com (Traducida de The Cochrane Library, Issue. Chichester, UK: John Wiley & Sons, Ltd.).

  17. Sajama C, Lorenzoni J, Tagle P. Diagnóstico y tratamiento de las metástasis encefálicas. Rev Med Chile. 2008;136(10):1321–6.

  18. Nathoo N, Chahlavi A, Barnett GH, Toms SA. Pathobiology of brain metastases. J Clin Pathol. 2005;58:237–42.




2020     |     www.medigraphic.com