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ISSN 2594-1526 (Electronic)
Antes Revista del Instituto Nacional de Enfermedades Respiratorias

 Ver anteriores al 2010

2014, Number 1

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Neumol Cir Torax 2014; 73 (1)

Current pharmacological treatment of pulmonary

Machado-Villarroel L, Gómez-Hernández G

Language: Spanish
References: 46
Page: 49-56
PDF size: 246.13 Kb.


ABSTRACT

Venous thromboembolism represents a spectrum of the same entity which includes pulmonary embolism and deep vein thrombosis. The conventional anticoagulation with unfractionated heparin and low-molecular-weight heparin for 5-10 days is the initial treatment of choice. Pulmonary embolism treatment typically continues with vitamin K antagonists between 3 and 6 months, in some cases anticoagulation is up to 1 year, due to the latency of risk factors. Several studies have confirmed the effectiveness and safety of low-molecular-weight heparin compared with unfractionated heparin in the acute phase treatment of pulmonary embolism; nowadays the use of the latter is routine in both prevention and treatment of deep-vein thrombosis. This differs from the treatment of massive and/or submassive pulmonary embolism requiring fibrinolytic therapy because mortality is up to 70%, strongly related to right ventricular failure and heart failure.


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