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2014, Number 2

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Rev Fac Med UNAM 2014; 57 (2)

Overwhelming postsplenectomy infection (OPSI) syndrome secondary to meningococcemia

Carrillo ER, Peña PCA, Carrillo CJR, Carrillo CLD, Carrillo CCA, Carrillo CDM

Language: Spanish
References: 55
Page: 31-41
PDF size: 260.86 Kb.


ABSTRACT

Patients with splenectomy or splenic dysfunction are likely to suffer from severe infections and sepsis. This syndrome is called overwhelming postsplenectomy infection (OPSI). We present the case of an adult who developed OPSI syndrome secondary to Neisseria meningitidis serogroup CR 7, ten years after being splenectomized due to idiopathic thrombocytopenic purpura. OPSI syndrome has a high mortality. Its course is fulminating, the clinical symptoms are serious and the prognosis is poor. It is important for splenectomized patients to receive immunizations, antibiotic prophylaxis and seek medical attention at the earliest sign of minor infection. Public health politics should be implemented for the development of guidelines related to the monitoring of splenectomized patients and prophylaxis, diagnosis and treatment of OPSI syndrome and make reliable information on this disease available to patients and physicians.


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