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Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado

2014, Number 1

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Rev Esp Med Quir 2014; 19 (1)

Subclinical hypothyroidism in patients with metabolic syndrome in the internal medicine consultation of a General Hospital in the city of Chihuahua

Monárrez TCE, Navarrete VR, Martínez TME, Hernández LAJ, Villegas SL

Language: Spanish
References: 21
Page: 23-29
PDF size: 553.63 Kb.


ABSTRACT

Background: In Latin America, up 75% of the deaths of adult people are produced as a consequence of chronic illness. Since of the decade of 70’s, it is well known that sub-clinical thyroid dysfunction is associated with an increased risk of cardiovascular diseases.
Objective: We aim to evaluate the prevalence of sub-clinical hypothyroidism (SCH) in metabolic syndrome (MetS) patients among the ambulatory adult-patients seen in the internal medicine section of a secondary care Hospital.
Material and Methods: A prospective, descriptive, analytical, crosssectional study was designed, in order to identify patients suffering of SCH and/or MetS. In this study were included 700 patients attending the external consult of internal medicine, at the Hospital General “Dr. Salvador Zubirán Anchondo” at Chihuahua City. Exclusion criteria were pregnant women, patients clinically diagnosed with thyroid diseases, and patients intreatment with anti-thyroid drugs, amiodarone, litium, interferons, or thyroid hormones.
Results: A MetS prevalence of 24% (168/700) was found. In 108 of these patients the level or thyroid hormone TSH was determined. The results revealed that 21.3% (23) of these patients showed a high level of TSH; the level detected was 10.83 ± 12.36. The findings of this study shown that most of the patients with MetS and both MetS plus SCH were women older than 55 yr old, which present high arterial pressure, altered prepandrial glucose, dyslipidemia and diabetes.
Discussion: The prevalence of MetS found in this study was 24%, and 21.3% of the patients presented sub-clinical hypothyroidism. The 56- 65 yr old etaric group was the most affected, and most of the patients (65.7%) were obese women. The prevalence of SCH reported in this study was higher than those previously reported in other studies.


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