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2013, Number 4

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Rev Cubana Estomatol 2013; 50 (4)

Diseases Bone Changes and changes in the Stomatognathic System Associated with Metabolic Endocrine Diseases

Matos PG, Andrade PP, Sacramento SM, Godoy FLM, Pedreira RLM, Almeida SV

Language: Portugués
References: 40
Page: 422-435
PDF size: 157.11 Kb.


ABSTRACT

Introduction: the prevalence of endocrine-metabolic diseases has increased in recent years due to improvement of the life expectancy of the population. Diabetes mellitus, hypothyroidism, hyperthyroidism, hypoparathyroidism and hyperparathyroidism may present alterations in the stomatognathic system; however, some studies found in literature are still limited in this area.
Objective: to address the characteristics and pathophysiological process of these diseases, especially bone changes and in the stomatognathic system.
Methods: data were collected through the selection of articles about bone alterations of the stomatognathic system associated with hypothyroidism, hyperthyroidism, hypoparathyroidism, hyperparathyroidism, and diabetes, published in databases, BIREME, MEDLINE and SciELO.
Results: seventy three articles published between 1995 y 2012 were revised, and 40 were selected on the basis of their association with the topic of interest. It has shown that changes in serum levels of thyroid and parathyroid hormones, and diabetes mellitus have an impact on bone metabolism. Delays in tooth eruption and exfoliation, bone growth and development are observed in hypothyroidism, whereas decreased bone mineral density, jawbones osteoporosis, accelerated exfoliation of deciduous teeth and premature eruption of permanent teeth were observed in hyperthyroidism. In hypoparathyroidism, there were osteosclerosis, hypoplastic teeth, and reduced bone remodeling. Intense osteoclastic activity, brown tumors and the absence of lamina dura in hyperparathyroidism may be observed. Diabetes mellitus can cause osteoporosis, periodontal disease and enamel hypoplasia. Although they are known, the magnitude and causes of these changes in the stomatognathic system are still unclear.
Conclusions: it is essential that dentist can recognize the local or systemic manifestations associated with these endocrine and metabolic disorders and help to early diagnosis and treatment.


REFERENCES

  1. Bensenor I. Screening for thyroid disorders in asymptomatic adults from Brasilian populations. São Paulo Med J. 2002;120(5):146-51.

  2. Nunes MT. Hormônios tireoidianos: mecanismo de ação e importância biológica. Arq Bras Encodrinol Metab. 2003;47(6):639-43.

  3. Roberts CGP, Ladenson PW. Hypothyroidism. The Lancet. 2004;363:793-803.

  4. Nogueira CR, Kimura ET, Carvalho GA, Sgarbi JA, Ward LS, Maciel LMZ et al. Hipotireoidismo: Diagnóstico. Associação Médica Brasileira e Agência Nacional de Saúde Suplementar; 2009. p. 1-18.

  5. Soldá AC. Efeito do laser em baixa intensidade em ratos wistar com hipotireoidismo induzido pelo propiltiouracil (PTU). São Paulo. Dissertação [Mestrado em Laser em Odontologia]Universidade de São Paulo; 2010. Disponible em: http://143.107.23.244/lelo/mestrado/PDF/Ana_Claudia.pdf

  6. Serakides R, Nunes VA, Ocarino NM, Nascimento EF. Efeito da Associação Hipertireoidismo-Castração no Osso de Ratas Adultas. Arq Bras Endocrinol Metab. 2004;48(6):875-84.

  7. Bassett JHD, Boyde A, Howell PGT, Bassett RH, Galliford TM, Archanco M, Evanse H, Lawsone MA, Crouchere P, Germain DLS, Galton VA, Williams GR. Optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts. Pnas. 2010;107(16).

  8. Roberts CGP, Ladenson PW. Hypothyroidism. The Lancet. 2004;363(9411):793-803.

  9. Buket A, Demet ST, Sema C, Behiye B. Dental Treatment way of Congenital Hypothyroidism: Case Report. International Dental and Medical Disoders. 2008;1(1):34-6.

  10. Gogakos AI, Bassett JHD, Williams GR, Thyroid and bone. Archives of Biochemistry and Biophysics. 2010;503(1):12936.

  11. Biron CR, RDH. Patients with thyroid dysfunctions require risk management before dental procedures. RDH. 1996;16(4):42-4.

  12. Singer PA, Cooper DS, Levy EG, Ladenson PW, Braverman LE, Daniels G et al. Treatment Guidelines for Patients With Hyperthyroidism and Hypothyroidism. JAMA. 1995;273(10):808-12.

  13. Feitosa DS, Marques MR, Casati MZ, Sallum EA, Nociti Jr FH, Toledo S. The influence of thyroid hormones on periodontitis-related bone loss and toothsupporting alveolar bone: a histological study in rats. J Periodont Res. 2009;44(4):4728.

  14. Attard NJ, George AZ. A Study of Dental Implants in Medically Treated Hypothyroid Patients. Clinical Implant Dentistry and Rescarch. 2002;4(4):220-31.

  15. Ribeiro AFC, Serakides R, Ocarino NM, Nunes VA. Efeito da Associação Hipotireoidismo-Castração no Osso e nas Paratireóides de Ratas Adultas. Arq Bras Endocrinol Metab. 2004; 48(4):525-34.

  16. Biondo-Simões MD, Ioshii SO, Borsato KS, Zimmermann E. O processo de cicatrização influenciado pelo hipotireoidismo e pelo envelhecimento. Estudo da cicatrização da parede abdominal, em ratos. Acta Cirúrgica Brasileira. 2005;20:120-8.

  17. Zimmermann E, Ribas-Filho J, Malafaia O, Ribas C, Nassif P, Stieven Filho E et al. Tracheal suture in rats with hypothyroidism. Wound healing study. Acta Cirúrgica Brasileira. 2009;24(4):282-9.

  18. Biondi B, Palmieri EA, Klain M, Schlumberger M, Filetti S, Lombardi G. Subclinical hyperthyroidism: clinical features and treatment options. European Journal of Endocrinology. 2005;152:19.

  19. Cardoso MJL, Muniz LMR, Gasparini TJ, Melussi M. Calcium homeostasis markers of bone metabolism in feline hyperthyroidism - a review. Archives of Veterinary Science 2007;12(1):17-27.

  20. Acotto CG, Niepomniszcze H, Vega E, Mautalen CA. Ultrasound parameters and markers of bone turnover in hyperthyroidism: a longitudinal study. J Clin Densitom. 2004;7(2):201-8.

  21. Cardoso MJL, CostaI FS, Muniz LMR, Melussi M, Valërio MA. Serum markers of bone metabolism in feline hyperthyroidism. Ciência Rural, Santa Maria. 2008;38(5):1368-74.

  22. Gouveia CHA. O efeito molecular e estrutural do hormônio tireoidiano no esqueleto. Arquivos Brasileiros de Endocrinologia e Metabologia. 2004;48:183-95.

  23. Karga H, Papapetrou PD, Korakovouni A, Papandroulaki F, Polymeris A, Pampouras G. Bone mineral density in hyperthyroidism. Clinical Endocrinology. 2004;61:466-72.

  24. Van de Ven AC, Erdtsieck RJ. Changes of bone mineral density, quantitative ultrasound parameters and markers of bone turnover during treatment of hyperthyroidism. Neth J Med. 2008;66(10):428-32.

  25. Barber PJ. Disordens of the parathyroid glands. Journal Feline Medicine Surgery. 2004;6:259-269.

  26. Mosekilde L. Primary hyperparathyroidism and the skeleton. Clinical Endocrinology. 2008;69 119.

  27. Guyton AC, Hall JE. Tratado de fisiologia médica. 11 ed. Rio de Janeiro: Elsevier; 2006.

  28. Rubin MR, Dempster DW, Zhou H, Shane E, Nickolas T, Sliney J Jr, et al. Dynamic and structural properties of the skeleton in hypoparathyroidism. J Bone Miner Res. 2008;23(12):2018-24.

  29. Moosgaard B, Vestergaard P, Heickendorff L, Melsen F, Christiansen P, Mosekilde L. Vitamin D status, seasonal variations, parathyroid adenoma weight and bone mineral density in primary hyperparathyroidism. Clinical Endocrinology. 2005;63:506-13.

  30. Kulak CAM, Dempster DW. Bone histomorphometry: a concise review for endocrinologists and clinicians. Arq Bras Endocrinol Metab. 2010;54(2):87-98.

  31. Alves, C.; Andion, J.; Brandão, M.; Menezes, R. Pathogenic aspects of the periodontal disease associated to diabetes mellitus Arq Bras Endocrinol Metab. 2007;51(7).

  32. Pippa Neto P, Sobrinho JA, Rapoport A. The importance for dental implant of the evaluation of osteoporosis women with type II diabetes mellitus aftermenopause. Rev Bras Cir Cabeça Pescoço. 2009;38(3):1716.

  33. Amorim JBO, Teixeira SS, Negrato GV, Vilela-Goulart MG, Gomes MF. Histomorphometric Analysis of Verapamil Effects on Alveolar Socket Repair on Diabetic Alloxan-Induced Rats. Cienc Odontol Bras. 2009;12(1):37-48.

  34. Akyol UK, Gungormus M. Effect of Biostimulation on Healing of Bone Defects in Diabetic Rats. Photomedicine and Laser Surgery. 2010;28(3):411-6.

  35. Esteves JC, Aranega AM, Borrasca AG, Fattah CMRS, Garcia Júnior IR. Repair process of surgical defects filled with autogenous bone grafts in tibiae of diabetic rats. J Appl Oral Sci. 2008;16(5):316-20.

  36. Villarino ME, Sánchez LM, Bozal CB, Ubios AM. Influence of short-term diabetes on osteocytic lacunae of alveolar bone. A histomorphometric study. Acta Odontol. Latinoam. 2006;19(1):23-8.

  37. Bayat M, Abdi S, Javadieh F, Mohsenifar Z, Rashid MR. The Effects of Low-Level Laser Therapy on Bone in Diabetic and Nondiabetic Rats. Photomedicine and Laser Surgery. 2009;27(5):703-8.

  38. Seal, B.L.; Otero, T.C.; Panitch, A. Polymeric biomaterials for tissue and organ regeneration. Materials Science Engineering R. 2001;34:147-230.

  39. Lumachi F, Camozzi V, Tombolan V, Luisetto G. Bone Mineral Density, Osteocalcin, and Bone-speciûc Alkaline Phosphatase in Patients with Insulindependent Diabetes Mellitus. Integrative Physiology: Ann N.Y. Acad Sci. 2009;1173:E64E67.

  40. Shu A, Yin MT, Stein E, Cremers S, Dworakowski E, Ives R et al. Bone structure and turnover in type 2 diabetes mellitus. Osteoporos Int. 2012;23:63541.




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