2014, Number 1
Infection by Acinetobacter spp. in the University Hospital
Language: Spanish
References: 21
Page: 3-14
PDF size: 235.73 Kb.
ABSTRACT
Infections associated to the sanitary care are serious public health problems at the international level because of their frequency and high mortality. In the last ten years, Acinetobacter spp. has emerged as an important nosocomial opportunistic pathogen. Among these species, A. baumanii (B Ab) is the main isolated species covering as many as 92 % of the nosocomial bacteremias. Most of the reports of nosocomial bacteremias by A. baumanii (B Ab) are outbreaks in adult patient intensive care units. It has been reported a boost of this germ antimicrobial resistance. We carried out a cross sectional, descriptive, observational study on Acinetobacter spp. infection, in the University Hospital “Comandante Faustino Pérez Hernández” of Matanzas municipality, from October 2011 to July 2012. Taking into account the absence of a previous study in Matanzas on infections caused by this microorganism, we decided identifying the Acinetobacter spp. incidence according to biological samples and coming-from service and identifying its sensibility/resistance, allowing the instauration of the efficacious treatment of the patients who carry this bacterium, considering the susceptibility pattern found in the study. The most frequently found species was A. baumanii, mainly in endotracheal secretions and hemo-cultures, most of them coming from Intensive Therapy Units, being this service the one contributing with more quantity of multidrug resistant stocks. We found a bigger sensibility to antimicrobials that are not considered first line ones like doxycycline, tetracycline and trimetoprim- ulfametoxazole.REFERENCES
Hart Casares M, Espinosa Rivera FI, Halley Posada MC. Resistencia a antibióticos en cepas de Acinetobacter baumannii aisladas de enero a marzo del 2010 en el Hospital Clínico quirúrgico "Hermanos Ameijeiras". Rev Cubana Medicina [Internet]. 2010[citado 16 Jun 2012];49(3). Disponible en:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232010000300001&lng=es&nrm=iso&tlng=es.
Hernández Torres A, García Vázquez E, Yague G, Gomez Gomez J. Acinetobacter baumanii multiresistente. Situación clínica actual y nuevas perspectivas. Rev Española Quimioter [Internet] 2010[citado 16 Jun 2012];23(1):12-9. Disponible en:http://www.seq.es/index2.php?option=com_content&task =view&id=383&pop=1&page=0&Itemid=1.
Akbari M, Niakan M, Taherikalani M, Feizabadi MM, Azadi NA, Soroush S, et al. Rapid identification of Iranian Acinetobacter baumanni strains by single PCR assay using BLAoxa-51–like carbapenemase and evaluation of the antimicrobial resistance profiles of the isolates. Acta Microbiol Inmunol Hung. 2010;57(2): 87-94. Citado en PUbMed; PMID: 20587382.
Hart Casares M, Llanes Rodríguez N, Espinosa Rivera F, Halley Posada MC, Martínez Batista ML, López Suárez AL. Estudio de la sensibilidad antimicrobiana de la especie Acinetobacter baumanii en el Hospital "Hermanos Ameijeiras" 2006. Rev Cubana de Med [Internet]. 2008[citado 16 Jun 2012];47(3). Disponible en: http://www.scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232008000300007&lng=es&nrm=iso&tlng=es
Mezzatesta ML, Trovato G, Gona F, Nicolosi VM, Nicolosi D, Carattoli A, et al. In vitro activity of tigecycline and comparators against carbapenem-susceptible and resistant Acinetobacter baumannii clinical isolates in Italy. Ann Clin Microbiol Antimicrob. 2008;7(4). Citado en PubMed; PMID: 18261233.
Adams-Haduch JM, Paterson DL, Sidjabat HE, Pasculle AW, Potoski Brian A, Muto CA, et al. Genetic Basic of Multidrug Resistance in Acinetobacter baumannii Clinical isolates at a Tertiary Medical Center in Pennsylvania. Antimicrobial Agents Chemother. 2008;52(11): 3837-43. Citado en PubMed; PMID: 18725452.