2014, Number 1
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AMC 2014; 18 (1)
Microfractures in patients with cartilage lesions of the knee treated by arthroscopy
Álvarez LA, Ortega GC, García LY, Díaz RJM
Language: Spanish
References: 42
Page: 55-68
PDF size: 259.30 Kb.
ABSTRACT
Background: cartilage lesions of the knee are difficult to treat because the healing process of this tissue is very low; that is why surgical procedures are the most used treatment for this complaint.
Objective: to evaluate the results of microfractures in patients suffering from cartilage lesions of the knee.
Methods: a cuasi-experimental study, before and after modality, without a control group was performed. The universe of investigation involved 65 patients with cartilage lesions of the knee diagnosed and treated by arthroscopy at Manuel Ascunce Domenech Provincial Teaching Hospital in Camaguey from January 1st, 2012 to January 31th, 2013. The non-probabilistic sample was composed of 43 patients who fitted the selection criteria.
Results: female sex predominated with a female-male proportion of 2, 9 to 1. Medial tibiofemoral compartment was the most affected with 23 patients for a 53, 4 %. Cartilage lesions between one and two centimeters were found in 24 patients for a 75 %. Of 43 studied patients, 32 presented associated intrarticular diseases for a 74, 4 %. The 65, 1 % of the patients had others factors associated to cartilage lesions of the knee. Unfavorable results were obtained in the 18, 3 % of the cases.
Conclusions: microfractures proved to be effective in more than three fourths of the studied patients.
REFERENCES
Álvarez López A, García Lorenzo Y, López Lastre G, López lastre M. Lesiones del cartílago de la rodilla. AMC. 2013 Ene-Feb;17(1):103-13.
Baum T, Joseph GB, Karampinos DC, Jungmann PM, Link TM, Bauer JS. Cartilage and meniscal T2 relaxation time as non-invasive biomarker for knee osteoarthritis and cartilage repair procedures. Osteoarthritis Cartilage. 2013 Oct;21(10):1474-84.
Hapa O, Barber A. Chondral injuries of the knee. En: Johnson DH, editor. Operative Arthroscopy. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2013. p. 719-45.
Henn RF, Gomoll AH. A review of the evaluation and management of cartilage defects in the knee. Phys Sportsmed. 2011 Feb;39(1):101-7.
Henry SE, Deasy BM, Chu CR. Articular cartilage: biology, biomechanics, and healing response. En: Scott WN, editor. Insall & Scott Surgery of the Knee. 5th ed. Philadelphia: Elsevier; 2012. p. 146-54.
Niemeyer P, Porichis S, Steinwachs M, Erggelet C, Kreuz PC, Schmal H, et al. Long-term Outcomes After First-Generation Autologous Chondrocyte Implantation for Cartilage Defects of the Knee. Am J Sports Med. 2014 Jan;42(1):150-7.
Versier G, Dubrana F. Treatment of knee cartilage defect in 2010. Orthop Traumatol Surg Res. 2011 Dec;97(8 Suppl):S140-53.
Stroh DA, Johnson AJ, Mont MA. Surgical implants and technologies for cartilage repair and preservation of the knee. Expert Rev Med Devices. 2011 May;8(3):339-56.
Noyes FR, Barber Westin SD. Advanced patellofemoral cartilage lesions in patients younger than 50 years of age: is there an ideal operative option? Arthroscopy. 2013 Aug;29(8):1423-36.
Behery O, Siston RA, Harris JD, Flanigan DC. Treatment of cartilage defects of the knee: expanding on the existing algorithm. Clin J Sport Med. 2014 Jan;24(1):21-30.
Enea D, Cecconi S, Calcagno S, Busilacchi A, Manzotti S, Kaps C, et al. Single-stage cartilage repair in the knee with microfracture covered with a resorbable polymer-based matrix and autologous bone marrow concentrate. Knee. 2013 Dec;20(6):562-9.
Bedi A, Feeley BT, Williams RJ. Management of articular cartilage defects of the knee. J Bone Joint Surg Am. 2010 Apr;92(4):994-1009.
Basad E, Ishaque B, Bachmann G, Starz H, Steinmeyer J. Matrix-induced autologous chondrocyte implantation versus microfracture in the treatment of cartilage defects of the knee: a 2-year randomised study. Knee Surg Sports Traumatol Arthrosc. 2010 Apr;18(4):519-27.
Hoemann CD, Gosselin Y, Chen H, Sun J, Hurtig MB, Carli A, et al. Characterization of initial microfracture defects in human condyles. J Knee Surg. 2013 Oct;26(5):347-55.
Lee KB, Wang VT, Chan YH, Hui JH. A novel, minimally-invasive technique of cartilage repair in the human knee using arthroscopic microfracture and injections of mesenchymal stem cells and hyaluronic acid a prospective comparative study on safety and short-term efficacy. Ann Acad Med Singapore. 2012 Nov;41(11):511-7.
Outerbridge RE. The etiology of chondromalacia patellae. J Bone Joint Surg Br. 1961 Nov;43:752-7.
Filardo G, Kon E, Andriolo L, Vannini F, Buda R, Ferruzzi A, et al. Does patient sex influence cartilage surgery outcome? Analysis of results at 5-year follow-up in a large cohort of patients treated with Matrix-assisted autologous chondrocyte transplantation. Am J Sports Med. 2013 Aug;41(8):1827-34.
Kreuz PC, Müller S, von Keudell A, Tischer T, Kaps C, Niemeyer P, et al. Influence of sex on the outcome of autologous chondrocyte implantation in chondral defects of the knee. Am J Sports Med. 2013 Jul;41(7):1541-8.
Cook JL, Farr J. Cartilage repair in the knee: part III. Foreword. J Knee Surg. 2012 May; 25(2):83.
Farr J, Cole B, Dhawan A, Kercher J, Sherman S. Clinical cartilage restoration: evolution and overview. Clin Orthop Relat Res. 2011 Oct;469(10):2696-705.
Balain B, Kerin C, Kanes G, Roberts SN, Rees D, Kuiper JH. Effects of knee compartment, concomitant surgery and smoking on medium-term outcome of microfracture. Knee. 2012 Aug;19(4):440-4.
Steadman JR, Rokey WG, Briggs KK. Debridment and microfracture for full thickness articular cartilage defects. En: Scott WN. Insall & Scott Surgery of the Knee. 5th ed. Philadelphia: Elsevier; 2012. p. 207-13.
Lim HC, Bae JH, Song SH, Park YE, Kim SJ. Current treatments of isolated articular cartilage lesions of the knee achieve similar outcomes. Clin Orthop Relat Res. 2012 Aug;470(8):2261-7.
Redler LH, Caldwell JM, Schulz BM, Levine WN. Management of articular cartilage defects of the knee. Phys Sportsmed. 2012 Feb;40(1):20-35.
Bae DK, Song SJ, Yoon KH, Heo DB, Kim TJ. Survival analysis of microfracture in the osteoarthritic knee-minimum 10-year follow-up. Arthroscopy. 2013 Feb;29(2):244-50.
Viste A, Piperno M, Desmarchelier R, Grosclaude S, Moyen B, Fessy MH. Autologous chondrocyte implantation for traumatic full-thickness cartilage defects of the knee in 14 patients: 6-year functional outcomes. Orthop Traumatol Surg Res. 2012 Nov;98(7):737-43.
Andro C, Dubrana F, Marcillaud G, Rouvillain JL, Gunepin FX, Dewerpe P, et al. Painful medial knee compartment syndrome in over 45 year-olds: medical or surgical management: a series of 174 patients. Orthop Traumatol Surg Res. 2011 Jun;97(4 Suppl):S21-6.
Nourissat G, Beaufils P, Charrois O, Selmi TA, Thoreux P, Moyen B. Magnetic resonance imaging as a tool to predict reparability of longitudinal full-thickness meniscus lesions. Knee Surg Sports Traumatol Arthrosc. 2008 May;16(5):482-6.
Álvarez López A, Ortega González C, García Lorenzo Y. Microfracturas por vía artroscópica en pacientes con osteoartritis de la rodilla. Rev Cub Ortop Traumatol. 2011 Aug-Dic;25(2):188-98.
Spahn G, Felmet G, Hofmann GO. Traumatic and degenerative cartilage lesions: arthroscopic differentiation using near infrared spectroscopy (NIRS). Arch Orthop Trauma Surg. 2013 Jul;133(7):997-1002.
Bowers AL, Wickiewicz TL. Clinical Approach to articular pathology. En: Johnson DH, editor. Operative Arthroscopy. 4 th ed. Philadelphia: Lippincott Williams & Wilkins; 2013. p. 703-9.
Harris JD, Brophy RH, Siston RA, Flanigan DC. Treatment of chondral defects in the athlete's knee. Arthroscopy. 2010 Jun;26(6):841-52.
Goyal D, Keyhani S, Lee EH, Hui JH. Evidence-based status of microfracture technique: a systematic review of level I and II studies. Arthroscopy. 2013 Sep;29(9):1579-88.
Rodriguez Merchant EC. The treatment of cartilage defects in the knee joint: microfracture, mosaicplasty, and autologous chondrocyte implantation. Am J Orthop (Belle Mead NJ). 2012 May;41(5):236-9.
Williams RJ, Brophy RH. Decision making in cartilage repair procedures. En: Williams RJ, editor. Cartilage Repair Strategies. New Jersey: Humana Press Inc; 2007. p. 37-53.
Widhalm HK, Marlovits S, Welsch GH, Dirisamer A, Neuhold A, van Griensven M, et al. Obesity-related juvenile form of cartilage lesions: a new affliction in the knees of morbidly obese children and adolescents. Eur Radiol. 2012 Mar;22(3):672-81.
Laberge MA, Baum T, Virayavanich W, Nardo L, Nevitt MC, Lynch J, et al. Obesity increases the prevalence and severity of focal knee abnormalities diagnosed using 3T MRI in middle aged subjects data from the Osteoarthritis Initiative. Skeletal Radiol. 2012 Jun;41(6):633-41.
Frank RM, Cole BJ. Complex cartilage cases in the athletic patient: advances in malalignment, instability, articular defects, and meniscal insufficiency. Phys Sportsmed. 2013 Nov;41(4):41-52.
Gomoll AH. Microfracture and augments. J Knee Surg. 2012 Mar;25(1):9-15.
Pascale W, Luraghi S, Perico L, Pascale V. Do microfractures improve high tibial osteotomy outcome? Orthopedics. 2011 Jul;34(7):e251-5.
Petri M, Broese M, Simon A, Liodakis E, Ettinger M, Guenther D. CaReS (MACT) versus microfracture in treating symptomatic patellofemoral cartilage defects: a retrospective matched pair analysis. J Orthop Sci. 2013 Jan;18(1):38-44.
Engelhart L, Nelson L, Lewis S, Mordin M, Demuro-Mercon C, Uddin S, et al. Validation of the Knee Injury and Osteoarthritis Outcome Score subscales for patients with articular cartilage lesions of the knee. Am J Sports Med. 2012 Oct;40(10):2264-72.