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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2013, Number 3

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Alerg Asma Inmunol Pediatr 2013; 22 (3)

Hemophagocytic lymphohistiocytosis and other hemophagocytic entities associated with intravenous gammaglobulin

Canell PR, Suárez AR, Rodríguez TJ, Hernández BVM, Vázquez GRE, Cerda RS

Language: Spanish
References: 63
Page: 114-120
PDF size: 133.87 Kb.


ABSTRACT

Autoimmune diseases are characterized by a immunological dysregulation; they present a misinterpretation by the patient’s immune system against it’s own antigen where takes place any hypersensibility response of Gel-Coombs mechanisms. There exist many kind of hemophagocytic syndromes, besides of it’s origin worldwide this entity has a high mortality and there’s no standardized therapeutic alternative. Diverse elements like etoposide, glucocorticoids, cyclosporine and also gammaglobulin to mention some have been used for trying to stop hemophagocytosis. In practice, Still disease has been increased in incidence, it can develop hemophagocytic syndrome, that’s why is important the clinical manifestations, workup and treatment.


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