Pérez CLM, Herrera VR, Fernández MI, Berlanga AJ, Villacís PD

Language: Spanish
References: 25
Page: 241-252
PDF size: 93.25 Kb.

ABSTRACT

Introduction. The prevalence of pediatric obesity has reached alarming figures at a worldwide level. Obesity is closely associated with glomerular hyperfitration, principally in adults. Methods. An observational, analytic and prospective study is presented that includes 202 children and obese adolescents attended in reference consultation in the Havana Center Pediatric Hospital. In all of the cases, physical measurements (weight, height, waist circumfe rence) were realized in addition to the calculation of the body mass index. Blood creatinine values were determined (Jaffé and enzymatic), cystatin C and glomerular filtrate rate was estimated. Total renal volume was determined with renal ecography. Results. Creatinine (Jaffé and enzymatic) and cystatin C levels was significantly lower in the obese group. The total renal volume was significantly higher in the obese. The obese group had a higher glomerular filtrate rate than the normal weight group with all methods. In the classification of glomerular filtrate rate in the obese group the number of obese with higher glomerular filtrate rate was significantly higher than obese with normal glomerular filtrate rate with all methods. Conclusions. The increase of glomerular filtrate rate associated of obesity is evident in early ages of the life.

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