medigraphic.com
SPANISH

Investigaciones Medicoquirúrgicas

ISSN 1995-9427 (Print)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2013, Number 2

<< Back Next >>

Invest Medicoquir 2013; 5 (2)

Microvascular angina in patients submissive coronary angiography

Aldama PLI, Aroche AR, Obregón SÁG, Padrón PR, Valdez DO
Full text How to cite this article

Language: Spanish
References: 16
Page: 213-220
PDF size: 211.09 Kb.


Key words:

microvascular angina, coronariogrphy, endotelial function.

ABSTRACT

Introduction. A substantial number of patients, who are going to coronariography, does not have atherosclerotic injuries in their coronary tree. The sub -group with anginous pain and positive stres s test includes itself in the diagnosis of microvascular angina. Methods. A descriptive transversal study was made, in patients studied in the CIMEQ homodynamic lab, between 2010 and 2011, with initial diagnosis of effort angina and positive stress test. T he universe was constituted by the 1452 patients submissive coronariography in this period. The sample was 452 in which injuries of coronary atherosclerosis were not demonstrated. Results. 31.1% of the patients submissive coronariography diagnostic of microvascular angina with greater prevalence of feminine sex. The arterial hypertension was the risk factor more prevalent in the evaluation time. Conclusions. The microvascular angina is a frequent disease in our means that are related to the presence of cardiovascular risk factors.


REFERENCES

  1. Kaski JC. Cardiac syndrome X and microvascular angina. In: Kaski JC, editor. Chest pain with normal coronary angiograms. Pathogenesis, diagnosis and management. Massachusetts: Norwell Kluwer Academic Publishers; 1999. p. 1-12.

  2. Kemp HG. Left ventricular function in patients with anginal syndrome and normal coronary arteriograms. Am J Cardiol 1973;32:375-6.

  3. Quyyumi AA, Mulcahy D, Andrews NP, Panza JA, Cannon RO. Coronary vascular nitric oxide activity in hypertension and hypercholesterolemia. Comparison of acetylcholine and substance P. Circulation 1997;95:104 -10.

  4. Johnson BD, Shaw LA, Buchthal SD, B airey Merz N, Kim HW, et al. Prognosis in women with myocardial ischemia in the absence of obstructive coronary disease. Circulation 2004;109:2993-99.

  5. Reis S, Holubkov R, Conrad Smith A, Kelsey S, Sharaf B, et al. Coronary microvascular dysfunction is highly prevalent in women with chest pain in the absence of coronary artery disease: results from the NHLBI WISE study. Am Heart J 2001;141:735-41.

  6. Kemp HG, Kronmal RA, Vliestra RE, Frye RL. Seven years survival of patients with normal or near normal coronary arteriograms: a CASS registry study. J Am Coll Cardiol 1986;7:479-83.

  7. Kaski JC, Rosano GM, Collins P, Nihoyannopoulos P, Maseri A, et al. Cardiac syndrome X. Clinical characteristics and left ventricular function. Long -term follow-up study. J Am Coll Cardiol 1995;25:807-15.

  8. Shaw LJ, Bugiardini R, Bairey Merz N. Women and ischemic heart disease. Evolving knowledge. J Am Coll Cardiol 2009;54:1561 -75.

  9. Rosano GM, Collins P, Kaski JC, Lindsay DC, Sarrel PM, et al. Syndrome X in women is associated with estrogen deficiency. Eur Heart J 1995;16:610 -4.

  10. Lanza GA, Crea F. Primary Coronary Microvascula r Dysfunction. Circulation 2010;121:2317-25.

  11. Oki T, Tabata T, Yamada H, Wakatsuki T, Mishiro Y, et al. Left ventricular diastolic properties of hypertensive patients measured by pulsed tissue Doppler imaging. J Am Soc Echocardiogr 1998;11:1106-12.

  12. Schafer S, Kelm M, Mingers S, S trauer BE. Left ventricular remodeling impairs coronary flow reserve in hypertensive patients. J Hypertens. 2002;20:1431 -7.

  13. Bugiardini R, Bairey Merz CN. Angina with «normal» coronary arteries: a changing philosophy. JAMA 2005;293:477-84.

  14. Johnson BD, Shaw LJ, Buchthal SD, Bairey Merz CN, Kim HW, et al. Prognosis in women with myocardial ischemia in the absence of obstructive coronary disease: results from the National Institutes of Health -National Heart, Lung, and Blood Institute - Sponsored Women’s Ischemia Syndrome Evaluation (WISE). Circulation 2004;109:2993-9.

  15. Bugiardini R, Manfrini O, Pizzi C, Fontana F, Morgagni G. Endothelial function predicts future development of coronary artery disease: a study of women with chest pain and normal coronary angiograms. Circulation 2004;109:2518-23.

  16. Vermeltfoort I, Bondarenko O, Raijma kers P, Odekerken D, Kuijper A, et al. Is subendocardial ischaemia present in patients with chest pain and normal coronary angiograms? A cardiovascular MR study. European Heart Journal 2007;28:1554-8.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Invest Medicoquir. 2013;5