2013, Number 3
Epithelial thymoma as a cause of thoracic pain during an atypical exacerbation of bronchial asthma: a case report
Language: Spanish
References: 7
Page: 300-305
PDF size: 234.87 Kb.
ABSTRACT
Background: the evaluation of a patient with bronchial asthma exacerbation includes the search for diseases which can simulate, complicate or perpetuate that situation. The retrosternal pain is an atypical symptom in patients with asthmatic exacerbation and among the causes that can originate this symptom are mediastinal masses like thymoma. A third part of patients with thymomas might have symptoms associated with autoimmune diseases and paraneoplastic syndromes; however, although asthma has an important immunologic component in its pathophysiology, association of thymoma with asthma is poorly documented.Objective: to offer a clinical lesson through a presentation of a case with unusual association of thymoma and asthma.
Case presentation: a 50 year-old female patient with asthmatic exacerbation and retrosternal thoracic pain came to emergency services. A mass in anterosuperior mediastinum was observed in computed tomographic high-resolution scan and after performing surgical exeresis and immune histochemistry studies an epithelial timoma type IIB was diagnosed.
Conclusions: the presence of unusual symptoms in a patient with asthma exacerbation led to an epithelial thymoma, even when there has not been shown association between these two diseases.
REFERENCES
Hoshino M, Nakagawa T, Sano Y, Hirai K. Effect of inhaled corticosteroid on an immunoreactive thymus and activation-regulated chemokine expression in the bronchial biopsies from asthmatics. En: The Cochrane Library. 2005 Mar [consultado 05-03-2013];60(3):317-22. Available from : http://cochrane.bvsalud.org/cochrane/main.php?lang=es&lib=COC
González R, Santolaya R, Jadue A, Prats R, Mordojovich G, Rodríguez P. Neoplasias epiteliales del timo: timoma y carcinoma tímico. Caracterización, tratamiento y variables asociadas a supervivencia. Rev Chil Cir [revista electrónica]. 2012;64(6) [consultado 23-01-2013]: Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-40262012000600007&lng=en&nrm=iso