2013, Number 6
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Acta Pediatr Mex 2013; 34 (6)
Treatment of myoclonic encephalopathy of childhood (Kinsbourne syndrome) with methotrexate and intravenous
Torres MD, Dávila GG, Hernández BVM, Vázquez EP, Rodríguez TJ
Language: Spanish
References: 14
Page: 370-373
PDF size: 247.47 Kb.
ABSTRACT
Myoclonic encephalopathy of infancy is an important model of
natural tumor regression. Patients with opsoclonus-myoclonus
generate an immune response against a variety of brain antigens.
It is probable that neuroblastoma (or viral antigens) and the cerebelum
are joint targets of an immunologic attack. Most cases
show a remarkable reponse to ACTH, intravenous gammaglobulin
and rituximab.
REFERENCES
Kaplan M, Salet J, Pean G. Sur une variété d`ataxie cérébelleuse acquise de I`enlance avec tremblement oculaire. Arch Fr Pédiatr. 1959;16:1124-1129.
Dávila-Gutiérrez G, García G. Encefalopatía mioclónica infantil. Experiencia de 27 años en el diagnóstico y tratamiento de la encefalopatía mioclónica infantil. Rev Mex Neuroci. 2009;10(2):151.
Artigas PE, Sánchez E, Marlon V, Dávila-Gutiérrez G. Tumores derivados de la cresta neural en pacientes con encefalopatía opsomioclónica (síndrome de Kinsbourne). Experiencia de 20 años en niños mexicanos. Acta Pediatr Mex. 2006;27(4):245-246.
Pranzatelli RM, Tate E, Traveistead L, Baumgarder A, Gorda B, Haltore N et al. Insights on chronic-relapsing opsoclonusmyoclonus from pilot study of mycophenolate mofetil. J Child Neurol. 2009;24:316-321.
Dávila-Gutiérrez G, Palacios-Acosta J, Guzmán-Martínez A, Rodríguez-Abarca F, Shalkow K, Carrasco-Daza D. Síndrome de opsoclonos mioclonos causado por neuroblastoma. Informe de un caso. Acta Pediatr Mex. 2010:31(1):36- 41.
Pranzatelli MR, Tate ED, Cowley JR, Tooennies B, Creer M. Neurometabolic effects of ACTH on free amino compounds in opsoclonus-myoclonus syndrome. Neuropediatrics 2008;39:164-171.
Ketterl T, Messinger Y, Niess D, Gilles E, Engel W, Perkins J. Ofatumumab for refractory opsoclonus-myclonus syndrome following treatment of neuroblastoma. Pediatr Blood Cancer. 2013;60:163-165.
Wilken B, Baumann M, Bien C, Hero B, Rostasy K, Henefeld F. Chronic relapsing opsoclonus myoclonus syndrome: Combination of cyclophosphamide and dexamethasone pulses. J Eur Pediatrics Neurol. 2008;12:51-55.
Pranzatelli RM, Tate E, Travelstead L, Baugarder A, Gorda V, Haltore N, et al. Insights on chronic-relapsing opsoclonusmyclonus from pilot study of mycophenolate mofetil. J Child Neurol. 2009;24:316-321.
Glatz K, Meinck H, Wildermann B. Parainfectious opsoclonusmyoclonus syndrome: high dose intravenous immunoglobulins are effective. J Neurol Neurosurg Psychiatry. 2003;74(2):279- 280.
Unal A, Sumer MM, Atasoy HT, Atasoy N. Treatment of idiopathic opsoclonus-myclonus syndrome with intravenous immunoglobulin. Neurol India. 2004;52(4):520-521.
Venesselli E, Conte M, Biancheri R, Acquaviva A, De Bernardi B. Effect of steroid and high-dose immunoglobulin therapy in opsoclonus-myclonus syndrome occurring in neuroblastoma. Med Pediatr Oncol. 1998;30:15-17.
Pranzatelli MR, Tate ED, Travelstead AL, Longee D. Immunologic and clinical responses to rituximab in a child with opsoclonus-myoclonus syndrome. Pediatrics. 2005;115:e115- e119.
Pranzatelli MR, Tate ED, Shenoy S, Travelstead AL. Ofatumumab for a rituximab-allergic child with chronic-relapsing paraneoplastic opsoclonus-myoclonus. Pediatr Blood Cancer. 2012;58(6):988-91.