2012, Number 4
<< Back Next >>
Med Sur 2012; 19 (4)
Síndrome anticolinérgico
Carrillo-Esper R, Ramírez-Rosillo FJ, Garnica-Escamilla MA, Méndez-García JA, Esquivel-Méndez S, Rocha-Rodríguez MG, Carrillo-Córdova CA
Language: Spanish
References: 12
Page: 244-249
PDF size: 225.46 Kb.
ABSTRACT
Anticholinergic syndrome is a complication of many drugs with antimuscarinic
effects. It is characterized by midriasis, motor incoordination,
nausea, vomiting, hallucinations, shivering, fever, dry mouth
and skin, taquicardia, photophobia, retention of urine, paralytic
ileus, delirium, confusion and coma. Because of multiplicity of factors
its diagnosis is clinical. The treatment is based on supportive
measurements and physostigmine. The aim of this paper is to report
a case of anticholinergic syndrome secondary to intoxication with
dyphenidramine and review the literature.
REFERENCES
Gómez PJ, Gutiérrez MB, Colunga SA, Santoyo MD. Síndrome anticolinérgico central: reporte de 2 casos. Rev Mex Anest 2003; 26: 25-7.
Parisi P, Francia A. A female with central anticholinergic syndrome responsive to neostigmine. Pediatr Neurol 2000; 23: 185-7.
Mandelli GR, Maiorana S, Terni P, Lamperti G, Colibretti ML, Imbimbo BP. Synthesis of new cardioselective M2 muscarinic receptor antagonists. Chem Pharm Bull 2000; 48: 1611-22.
Link J. Distinct central anticolinergic syndrome following general anesthesia. Eur J Anaesthesiol 1997; 14: 15-23.
Rupreht J. The central muscarinic transmission during anaesthesia and recovery- the central anthicolinergic syndrome. Anaesthesiol 1991; 16: 250-8.
Forrer G, Miller J. Atropine coma: asomatic therapy in psychiatry. Am J Psychiatry 1958; 115: 455-45.
Longo VG, Baldessarini R. Behavioral and electroencephalographic effects of atropine and related compounds. Pharmacol Rev 1966; 18: 965-96.
Brown DV, Heller F. Anticholinergic syndrome after anesthesia: a case report and review. Am J Ther 2004; 11: 144-53.
Frampton A, Spinks J. Hyperthermia associated with central anticholinergic syndrome caused by a transdermal hyoscine patch in a child with cerebral palsy. Emerg Med J 2005; 22: 678-9. Órgano de Difusión de la Sociedad de Médicos Revista de Investigación
Burns MJ, Linden CH, Graudins A. A comparison of physostigmine and benzodiazepines for the treatment of anticholinergic poisoning. Ann Emerg Med 2000; 35: 374-81.
Boyer EW. The Serotonin Syndrome. N Engl J Med 2005; 352: 1112-20.
Keulenaer BL. Central anticholinergic syndrome in the intensive care unit. Eur J Anaesthesiol 2004; 21: 496-503.