2012, Number 4
Next >>
Med Sur 2012; 19 (4)
Malformaciones müllerianas e infertilidad femenina
Escalona-García B, Pichardo-Cuevas M, Miranda-Rodríguez JA, Ramírez-Montiel ML, Contreras-Carreto NA
Language: Spanish
References: 14
Page: 200-202
PDF size: 108.59 Kb.
ABSTRACT
Introduction. Müllerian malformations are a specific group of
congenital diseases. There are caused by an inappropriate development
of the Müller structures. These malformations affect the
genitourinary system. The uterus is the most affected organ.
The incidence of this disease is unknown. These types of malformations
are diagnosed until gynecologic or urologic symptoms develop.
Objective. To determine the incidence of müllerian defects in
women diagnosed with infertility.
Material and methods. This
is a descriptive, observational and retrospective study. The patients
were women treated in the Infertility Clinic of the Hospital de la
Mujer (Mexico City). Only women diagnosed with müllerian malformations
corroborated with laparoscopy and hysteroscopy, from
January 1st 2008 to June 1st 2011, were included.
Results. The
main müllerian malformations encountered were as follows: uterine
hypoplasia/agenesia 12.5% (n = 2), didelphic uterus 6.3% (n = 1),
bicornuate uterus 25% (n = 4), septated uterus 50% (n = 8) and
arcuate uterus 6.3% (n = 1).
Conclusion. The incidence of müllerian
malformations in our hospital coincide with the one described
in the literature. The most common müllerian malformation was the
septated uterus (50%). It is fundamental to establish a correct diagnosis
in these patients in order to offer them the optimal infertility
treatment.
REFERENCES
Jara VCA, Rengifo C JM, Arango MA. Müller ducts abnormalities, prevalence at the Medellín General Hospital (2000-2005). Rev Colomb Obstet Ginecol 2006; 57: 82-7.
Rackow BW, Arici A. Reproductive performance of women with müllerian anomalies. Curr Opin Obstet Gynecol 2007; 19: 229-37.
Gurtcheff SE, Hatasaka H, Lambert P, Empey R, Morris E, Hammoud A. Clinical presentation of Müllerian anomalies in a large population cohort. Fertility and Sterility 2008; 90: 153-64.
Shulman LP. Müllerian anomalies, clinical obstetrics and gynecology 2008; 51: 214-22.
Raga F, Baustet C, Remohí J, Bonilla-Musoles F, Simon C, Pellicer A. Reproductive impact of congenital müllerian anomalies. Human Reproduction 1997; 12: 2277-81.
Mazouni C, Girard G, Deter R, Haumonte JB, Blanc B, Bretelle F. Diagnoss of müllerian anomalies in adults: evaluation and practice. Fertil Steril 2008; 89: 219-22.
Mucowski SJ, Herndon CN, Rosen MP. The arcuate uterine anomaly: a critical appraisal of its diagnosticand clinical relevance. Obstet Gynecol Surv 2010; 65: 449-54.
Sotirios HS, Karen AC, Tin-Chiu Li. Prevalence and diagnosis of congenital uterine anomalies in women with reproductive failure: a critical appraisal. Hum Reprod Update 2008; 14: 415-29.
Oppelt P, Renner SP, Brucker S, Strissel PL, Strick R. The VCUAM (Vagina, Cervix, Uterus and Adnex-associated Malformation) Classification: a new Classification for genial malformations. Fertil Steril 2005; 84: 1493-7.
Butram VC. Müllerian anomalies and their management, Fertil Steril 1983; 40: 159-63.
Templeman CL, Lam AM, Hertweck SP. Surgical management of vaginal agenesis. Obstet Gynecol Surv 1999; 54: 583-91.
Troiano RN, McCarthy SM. Müllerian duct anomalies: imaging and clinical issues. Radiology 2004; 233: 19-34.
Propst AM, Hill JA 3rd. Anatomic factors associated with recurrent pregnancy loss. Semin Reprod Med 2000; 18: 341-50.
Grimbizis GF, Camus M, Tarlatzis BC, Bontis JN, Devroey P. Clinical implications of uterine malformations and hysteroscopic treatment results. Hum Reprod Update 2001; 7: 161-74.