2012, Number 4
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Rev Latinoam Psiquiatría 2012; 11 (4)
Estudios de neuroimagen estructural en pacientes con diagnóstico de esquizofrenia
Ramírez-Bermúdez J, Valadez J, León-Ortiz P, de la Fuente-Sandoval C
Language: Spanish
References: 11
Page: 164-167
PDF size: 435.39 Kb.
ABSTRACT
Structural brain imaging techniques represent a valuable source
of information regarding de nervous system abnormalities in subjects
with a schizophrenia diagnosis. Magnetic resonance imaging
voxel-based morphometry allows us to explore the grey matter
brain regions with volumetric deficits. By means of this technique it
is possible to conclude that the most consistent deficits have been
found, at least, in the following structures: left medial temporal lobe,
left superior temporal gyrus, left medial frontal gyrus, left parahipocampal
gyrus, right superior temporal gyrus. In a complementary
form, Magnetic Resonancia Diffusion Tensor Imaging provides a
source to explore abnormalities in white matter structural connectivity.
By means of this technique, in may be established that the
most consistent abnormalities in white matter connections include,
at least, the following: uncinated fasciculus, cingulum, and arcuate
fasciculus. Structural brain imaging support the hypothesis of
robust abnormalities in the brain architecture of subjects with a
schizophrenia diagnosis.
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