2013, Number 6
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Med Int Mex 2013; 29 (6)
Thymoma Type B2 with Metastasis to the Central Nervous System non-Receiving in PET-CT
Rojas-Sotelo M, Solís-Ayala E, Bourlon-Cuéllar RA, Bourlon-de los Ríos MT, Quiroz-Castro O, Quiroz-Casian L
Language: Spanish
References: 14
Page: 650-653
PDF size: 610.65 Kb.
ABSTRACT
Type B2 thymoma is approximately 20 to 36% of all thymomas
and represents 71% of paraneoplastic disorders, including
myasthenia gravis. Distant metastasis is ‹ 7%, involving lung,
liver, bone and brain, being more frequent the local, pleura
and mediastinal nodes. According to findings of Adams and
Kubota, the capture of flurodeoxyglucosa (FDG) is related
to the invasive capacity of thymic carcinoma, which would
raise the possibility of using FDG PET for diagnosis, planning
treatment and to monitor recurrences; however, its utility
has not been proved.
REFERENCES
Rosai J. Histological typing of tumors of the thymus. 2nd ed. New York: Springer-Verlag, 1999.
Kelly RJ, Petrini I, Rajan A, Wang Y, Giaconne G. Thymic malignancies: from clinical management to targeted therapies. J Clin Oncol 2011;29:4820-4827.
Baas P, Rhodius R. Thymoma Update 2011. Netherlands Cancer Institute, Department of Thoracic Oncology. Eur J Cancer 2011;47:S315.
Eng TY, Fuller CD, Jagirdar J, Bains Y, Thomas CR. Thymic carcinoma: State of the Art Review. Int J Radiat Oncol Biol Phys 2004;59:654-664.
Okumura M, Ohta M, Tateyama H, Nakagawa K, et al. The World Health Organization histologic classification system reflects the oncologic behavior of thymoma: a clinical study of 273 patients. Cancer 2002;94:624-632.
Detterback F, Youssef S, Ruffini E, Okumura M. A review of prognostic factors in thymic malignancies. J Thorac Oncol 2011;6:1698-1704.
López J, García J. Síndromes paraneoplásicos neurológicos. Arch Med 2007;3:1-8.
Evoli A, Minisci C, Di Schino C, Marsili F, et al. Thymoma in patients with MG: characteristics and long-term outcome. Neurology 2002;59:1844.
Ohata N, Usami N, Kawaguchi K, Tateyama H, Yokoi K. Type AB thymoma with brain metastasis: Report of a case. Surg Today 2011;41:1436-1438.
Ersahin M, Kilic K, Gögüsgeren MA, Bakirci A, et al. Multiple brain metastases from malignant thymoma. Case Reports. J Clin Neurosci 2007;14:1116-1120.
Davenport E, Malthaner RA. The role of surgery in the management of thymoma: a systematic review. Ann Thorac Surg 2008;86:673.
Rena O, Papalia E, Maggi G, Oliaro A, et al. World Health Organization histologic classification: an independent prognostic factor in resected thymomas. Lung Cancer 2005;50:59.
Choi KD, Kim JS, Park SH, Kim YK, et al. Cerebellar hypermetabolism in paraneoplastic cerebellar degeneration. J Neurol Neurosurg Psychiatry 2006;77:525.
Patel RR, Subramaniam RM, Mandrekar JN, Hammack JE, et al. Occult malignancy in patients with suspected paraneoplastic neurologic syndromes: value of positron emission tomography in diagnosis. Mayo Clin Proc 2008;83:917.