2013, Number 4
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Otorrinolaringología 2013; 58 (4)
Helicobacter pylori in Recurrent Respiratory Papillomatosis: Incidence and Influence on Clinical Course
Akaki CM, Guzmán RAK, Waller GLA, Segura GE
Language: Spanish
References: 19
Page: 212-216
PDF size: 377.99 Kb.
ABSTRACT
Background
Recurrent respiratory papillomatosis remains a disease with no cure
that causes significant biopsychosocial health impacts in patients,
besides representing expenses up to 474,000 dollars for the individual
treatment of this disease in a patient whose onset is from infancy.
Helicobacter pylori is a bacterium that colonizes the aerodigestive
tract, causing inflammation and mucosal damage, factors related to
the pathophysiology of recurrent respiratory papillomatosis.
Objective
To study the association between the presence of Helicobacter pylori
with the clinical course of the recurrent respiratory papillomatosis, to
find evidence to justify or not the use of treatment for eradication of
this bacterium in patients with recurrent respiratory papillomatosis.
Material and method
A subexperimental, observational, prospective study with a consecutive
sample of patients with recurrent respiratory papillomatosis, in
which presence of H. pylori was studied as well as its association to
clinical course of the disease.
Results
From our sample of seven patients, only three resulted positive to
Helicobacter. When comparing the index relapses/year to the presence
of H. pylori we found that there is not a direct association in patients.
Conclusions
The presence of H. pylori is not a factor in the course of recurrent
respiratory papillomatosis. There is no conclusive data proving the
scheme indicate eradication of H. pylori in patients with RRP
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