2013, Number 2
<< Back Next >>
Rev Mex Ortop Ped 2013; 15 (2)
Prevalence of pediatric syndromes in patients hospitalized for orthopedic surgery
Pardini ACG, Fuentes FS
Language: Spanish
References: 56
Page: 98-104
PDF size: 119.44 Kb.
ABSTRACT
Background: The term «pediatric syndrome» is called the association of two or more defects of prenatal origin due to a common causal factor. World reported 3% of all live births have some congenital malformations, it is estimated that there is an incidence of 5/1,000 live births orthopedic genetic abnormalities.
Objective: Identify the prevalence of pediatric syndromes in patients with orthopedic disturbance.
Methods: We conducted a retrospective study, descriptive, cross-sectional, non-probability sampling of consecutive cases, recorded pediatric syndrome, disorders orthopedic and surgery performed.
Results: 2,336 patients, 119 patients diagnosed with pediatric syndrome being a prevalence of 5%. Most common age of diagnosis was one year. The most common orthopedic diagnoses were congenital clubfoot (42.9%), scoliosis (16.8%), and developmental dysplasia of the hip (14.3%). The most common pediatric syndromes were arthrogrypotic syndrome (37%), Moebius syndrome (10.1%) and Down syndrome (8.4%). The most common orthopedic treatments were posteromedial release surgery (34.5%), alignment knee surgery (12.6%) and reduced hip and spine surgery (10%).
Conclusion: The treatment for orthopedic disorders accompanying a pediatric syndrome is more radical or aggressive than those with common orthopedic pathology.
REFERENCES
Joseph B, Nayagam S, Loder S, Torode S. Pediatric orthopaedics, a system of decision-making. Hodder Arnold; 2009: pp. 5-6.
Aviña Fierro JA, Tastekin A. Malformaciones congénitas: clasificación y bases morfogénicas. Rev Mex Pediatr. 2008; 75(2): 71-74.
Ugarte P. Congenital “muscle-skeletal” malformations. Rev Horizonte Médico. 2010; (10): 60-65.
Van Regemorter N, Dodion J, Druart C. Congenital malformations in 10,000 consecutive births in a university hospital: need for genetic counseling and diagnosis. J Pediatr. 1984; 386-390.
Libro síndromes pediátricos. pp. 15-18.
Aviña Fierro JA, Terrence WB. Síndrome dismórfico con anomalías congénitas múltiples: clasificación actual. Rev Mex Pediatr. 2009; 76(3): 132-135.
Skaggs DL, Flynn JM. Staying out of trouble in pediatric orthopaedics. Lippincott Williams and Wilkins; 2006: pp. 172-175.
Ortiz MR, Flores G, Cardiel LE, Luna RC. Frecuencia de malformaciones congénitas en el área de neonatología del Hospital General de México. Rev Mex Pediatr. 2003; 70(3): 128-131.
Cummings RJ, Davidson RS, Armstrong PF, Lehman WB. Congenital clubfoot. J Bone Joint Surg Am. 2002; 84A(2): 290-308.
Dobbs MB, Gurnett CA. Update on clubfoot: etiology and treatment. Clin Orthop Relat Res. 2009; 467(5): 1146-1153.
Ippolito E. Update on pathologic anatomy of clubfoot. J Pediatr Orthop B. 1995; 4(1): 17-24.
Romero A, Martínez N. Tratamiento del pie equinovaro aducto mediante la incisión tipo Cincinnati en el Hospital para el Niño Poblano. Act Ortop Mex. 2006; 20(5): 201-205.
Chan G, Dormans J. Update on congenital spinal deformities. SPINE. 2009; 34(17): 1766-1774.
Hedequist D, Emans J. Congenital scoliosis. J Pediatr Orthop. 2007; 27(1): 106-116.
Ruiz C, Ávila M, Suárez C, Trueba C. Asociación de hueso intercalar cervical y espina bífida oculta lumbar y sacra en un mismo paciente. Act Ortop Mex. 2009; 23(1): 31-34.
Farley FA, Hall J, Goldstein SA. Characteristics of congenital scoliosis in a mouse model. J Pediatr Orthop. 2006; 26: 341-346.
Loder RT, Hernández MJ, Lerner AL. The induction of congenital spinal deformities in mice by maternal carbon monoxide exposure. J Pediatr Orthop. 2000; 20: 662-666.
Campbell RM, Smith MD. Thoracic insufficiency syndrome and exotic scoliosis. J Bone Joint Surg Am. 2007; 89 (Suppl. 1): 108-122.
Kutlu A, Memik R, Mutlu M, Kutlu R, Arslan A. Congenital dislocation of the hip and its relation to swaddling used in Turkey. J Pediatr Orthop. 1992; 12(5): 598-602.
Stevenson DA, Mineau G, Kerber RA, Viskochil DH, Schaefer C, Roach JW. Familiar predisposition to developmental dysplasia of the hip. J Pediatr Orthop. 2009; 29(5): 463-466.
Finne PH, Dalen I, Ikonomou N, Ulimoen G, Ruud Hansen TW. Diagnosis of congenital hip dysplasia in the newborn. Act Orthop. 2008; 79(3): 313-320.
Boere-Boonekamp M, Toon H, Kerkhoff MD, Schuil P, Zielhuis G. Early detection of developmental dysplasia of the hip in the netherlands: the validity of a standardized assessment protocol in infants. American Journal of Public Health.1998; 88(2): 285-288.
Tachdjan M. Artrogriposis congénita múltiple. En: Ortopedia pediátrica. 2a ed. USA: Editorial Interamericana-McGraw-Hill; 1990: Tomo III pp. 2251-2287.
Eriksson M, Gutiérrez-Farewik EM, Broström E, Bartonek A. Gait in children with arthrogryposis multiplex congenita. J Child Orthop. 2010; 4(1): 21-31.
O’Flaherty P. Arthrogryposis multiplex congenital. Neonatal Netw. 2001; 20(4): 13-20.
Francois F, Reggie H. Orthopaedic know ledge update. Pediatrics 3. Editado por American Academy Orthopaedic of surgeons; pp. 137-144.
Kowalczyk B, Lejman T. Short-term experience with Ponseti casting and the Achilles tenotomy method for clubfeet treatment in arthrogryposis multiplex congenital. J Child Orthop. 2008; 2(5): 365-371.
Greggi T, Martikos K, Pipitone E, Lolli F, Vommaro F, Maredi E et al. Surgical treatment of scoliosis in a rare disease: arthrogryposis. Scoliosis. 2010; 9(5): 24.
Lora F, Certain J. Mobious syndrome with VIII cranial nerve involvement. Acta de Otorrinolaringología & Cirugía de Cabeza y Cuello. 2009; 37(1): 47-51.
Lipson T, Webster W, Weaver D. The Moebius syndrome: aetiology, incidence of mental retardation, and genetics. J Med Genet. 1991; 28(1): 18-26.
Kumar D. Moebius syndrome. J Med Genet. 1990; 27(2): 122-126.
Cammarata F. Clinical and etiological spectrum of Mobius síndrome. Arch Argent Pediatr. 2007; 105(5): 444-446.
Al Kaissi K, Klaushofer K, Grill F. Occipito-vertebral dissociation in connection with extensive cervical spine malsegmentation in a boy with Mobius syndrome. Clinics. 2009; 64(10): 1034-1036.
Ochoa M, Trujillo C, Aguinaga M, Ríos B, Ibarra J, Gilda D. Secuencia de Moebius: reporte de cinco casos y revisión de literatura. Perinatol Reprod Hum. 2008; 22: 315-323.
Roizen N, Patterson D. Down’s syndrome. Lancet. 2003; 361: 1281-1289.
Baum R, Nash P, Foster J, Spader M, Ratliff SK, Coury D. Management of Down syndrome in primary care. Curr Probl Pediatr Adolesc Health Care. 2008; 38: 241-261.
Tachdjan M. Síndrome de Down. En: Ortopedia pediátrica. 2a ed. USA: Editorial Interamericana-McGraw-Hill; 1990: Tomo I pp. 961-967.
Concolino D, Pasquzzi A, Capalbo G, Sinopoli S, Strisciuglio P. Early detection of pediatric anomalies in children with down syndrome. Acta Paediatrica. 2006; 95: 17-20.
Bettuzzi C, Lampasi M, Magnani M, Donzelli O. Surgical treatment of patellar dislocation in children with Down syndrome: a 3-to 11-year follow-up study. Knee Surg Sports Traumatol Arthrosc. 2009; 17: 334-340.
Albareda A, Bello M, Martín P, Aznar J, Seral F. Luxación de cadera en el síndrome de Down. Rev Esp De Cir Ost. 1988; 111-120.
Harbir J, Emery H. The arthropathy of Down syndrome: an underdiagnosed and under-recognized condition. J Pediatr. 2009; 154: 234-238.
Diamond LS, Lynne D, Sigman B. Orthopedic disorders in patiens with Down’s syndrome. Orthop Clin North Am. 12: 57-71.
Jouhilahti EM, Peltonen S, Heape AM, Peltonen J. The pathoetiology of neurofibromatosis 1. Am J Pathol. 2011; 178(5): 1932-1939.
Boyd KP, Korf BR, Theos A. Neurofibromatosis type 1. J Am Acad Dermatol. 2009; 61(1): 1-14.
Gkiokas A, Hadzimichalis S, Vasiliadis E, Katsalouli M, Kannas G. Painful rib hump: a new clinical sign for detecting intraspinal rib displacement in scoliosis due to neurofibromatosis. Scoliosis. 2006; 14: 1-10.
Williams VC, Lucas J, Babcock MA, Gutmann DH, Korf B, Maria BL. Neurofibromatosis type 1 revisited. Pediatrics. 2009; 123(1): 124-133.
Shirley ED, Sponseller PD. Marfan syndrome. J Am Acad Orthop Surg. 2009; 17(9): 572-581.
Judge D, Dietz H. Marfan’s Syndrome. Lancet. 2005; 366: 1965-1976.
Oliva P, Moreno R, Toledo I. Marfan síndrome. Rev Med Chile. 2006; 134: 1455-1464.
Ammash N, Sundt T, Connolly H. Marfan syndrome: diagnosis and management. Curr Probl Cardiol. 2008; 33: 7-39.
Avivi A, Arzi H, Paz L, Caspi I, Chechik A. Skeletal manifestations of Marfan syndrome. IMAJ. 2008; 10: 186-188.
Gray J, Bridges A, Faed M, Pringle T, Baines P, Dean J et al. Ascertainment and severity of Marfan syndrome in a Scottish population. J Med Genet. 1994; 31(1): 51-54.
Tachdjan M. Síndrome de Marfan. En: Ortopedia pediátrica. 2a ed. USA: Editorial Interamericana-McGraw-Hill; 1990: Tomo II pp. 894-900.
Glard Y, Pomero V, Collignon P, Skalli W, Jouve J, Bollini G. Sagittal balance in scoliosis associated with Marfan syndrome: a stereoradiographic three-dimensional analysis. J Child Orthop. 2008; 2: 113-118.
Voermans NC, Hosman A, Van Alfen N, Bartels R, Kleuver M, Akker J et al. Radicular dysfunction due to spinal deformities in Marfan syndrome at older age: three case reports. European Journal of Medical Genetics. 2010; 53: 35-39.
Sponseller P, Jones K, Ahn N, Erkula G, Foran J, Dietz H. Protrusio acetabuli in Marfan syndrome: age-related prevalence and associated hip function. J of Bone & Joint Surg. 2006; 88A(3): 487-494.